Amanda MacFarlane
Amanda MacFarlane
Research Scientist, Health Canada
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Pre-conception folic acid and multivitamin supplementation for the primary and secondary prevention of neural tube defects and other folic acid-sensitive congenital anomalies
RD Wilson, F Audibert, JA Brock, J Carroll, L Cartier, A Gagnon, ...
Journal of Obstetrics and Gynaecology Canada 37 (6), 534-549, 2015
Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey
AJ MacFarlane, LS Greene-Finestone, Y Shi
The American journal of clinical nutrition 94 (4), 1079-1087, 2011
Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice
AJ MacFarlane, X Liu, CA Perry, P Flodby, RH Allen, SP Stabler, ...
Journal of Biological Chemistry 283 (38), 25846-25853, 2008
A type 1 diabetes-related protein from wheat (Triticum aestivum): cDNA clone of a wheat storage globulin, Glb1, linked to islet damage
AJ MacFarlane, KM Burghardt, J Kelly, T Simell, O Simell, I Altosaar, ...
Journal of Biological Chemistry 278 (1), 54-63, 2003
Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group
EA Yetley, AJ MacFarlane, LS Greene-Finestone, C Garza, JD Ard, ...
The American journal of clinical nutrition 105 (1), 249S-285S, 2017
Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes
AJ MacFarlane, A Strom, FW Scott
Mammalian genome 20 (9), 624-632, 2009
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism
AJ MacFarlane, CA Perry, HH Girnary, D Gao, RH Allen, SP Stabler, ...
Journal of Biological Chemistry 284 (3), 1533-1539, 2009
High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism
M Aarabi, MC San Gabriel, D Chan, NA Behan, M Caron, T Pastinen, ...
Human molecular genetics 24 (22), 6301-6313, 2015
Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA
AJ MacFarlane, DD Anderson, P Flodby, CA Perry, RH Allen, SP Stabler, ...
Journal of Biological Chemistry 286 (51), 44015-44022, 2011
Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation
L Ly, D Chan, M Aarabi, M Landry, NA Behan, AJ MacFarlane, J Trasler
MHR: Basic science of reproductive medicine 23 (7), 461-477, 2017
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population
JWR Zinck, M de Groh, AJ MacFarlane
The American journal of clinical nutrition 101 (6), 1295-304, 2015
Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers
AJ MacFarlane, PJ Stover
Nutrition reviews 65 (suppl_3), S157-S166, 2007
Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice
BG Swayne, A Kawata, NA Behan, A Williams, MG Wade, AJ MacFarlane, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 737 (1 …, 2012
Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apcmin-mediated intestinal cancer risk
AJ MacFarlane, CA Perry, MF McEntee, DM Lin, PJ Stover
Cancer research 71 (6), 2098-2107, 2011
Periconceptional intake of folic acid among low-risk women in Canada: summary of a workshop aiming to align prenatal folic acid supplement composition with current expert …
Y Lamers, AJ MacFarlane, DL O'Connor, B Fontaine-Bisson
The American journal of clinical nutrition 108 (6), 1357-1368, 2018
B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke
NM Jadavji, JT Emmerson, AJ MacFarlane, WG Willmore, PD Smith
Neurobiology of disease 103, 89-100, 2017
Effect of folic acid on human trophoblast health and function in vitro
T Ahmed, I Fellus, J Gaudet, AJ MacFarlane, B Fontaine-Bisson, ...
Placenta 37, 7-15, 2016
Mechanisms of oocyte aneuploidy associated with advanced maternal age
M Mikwar, AJ MacFarlane, F Marchetti
Mutation Research/Reviews in Mutation Research, 108320, 2020
Identification of three wheat globulin genes by screening a Triticum aestivum BAC genomic library with cDNA from a diabetes-associated globulin
E Loit, CW Melnyk, AJ MacFarlane, FW Scott, I Altosaar
BMC plant biology 9 (1), 1-11, 2009
Total folate and unmetabolized folic acid in the breast milk of a cross-section of Canadian women
R Page, A Robichaud, TE Arbuckle, WD Fraser, AJ MacFarlane
The American journal of clinical nutrition 105 (5), 1101-1109, 2017
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