Jeremy Draghi
Jeremy Draghi
Biological Sciences, Virginia Tech
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Mutational robustness can facilitate adaptation
JA Draghi, TL Parsons, GP Wagner, JB Plotkin
Nature 463 (7279), 353-355, 2010
Phenotypic plasticity facilitates mutational variance, genetic variance, and evolvability along the major axis of environmental variation
JA Draghi, MC Whitlock
Evolution: International Journal of Organic Evolution 66 (9), 2891-2902, 2012
Evolution of evolvability in a developmental model
J Draghi, GP Wagner
Evolution: International Journal of Organic Evolution 62 (2), 301-315, 2008
The evolutionary dynamics of evolvability in a gene network model
J Draghi, GP Wagner
Journal of evolutionary biology 22 (3), 599-611, 2009
Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations
HH Chou, NF Delaney, JA Draghi, CJ Marx
PLoS genetics 10 (2), 2014
Selection biases the prevalence and type of epistasis along adaptive trajectories
JA Draghi, JB Plotkin
Evolution 67 (11), 3120-3131, 2013
Local adaptation interacts with expansion load during range expansion: maladaptation reduces expansion load
KJ Gilbert, NP Sharp, AL Angert, GL Conte, JA Draghi, F Guillaume, ...
The American Naturalist 189 (4), 368-380, 2017
DNA secretion and gene-level selection in bacteria
JA Draghi, PE Turner
Microbiology 152 (9), 2683-2688, 2006
Evolution of evolvability
GP Wagner, J Draghi
Epistasis increases the rate of conditionally neutral substitution in an adapting population
JA Draghi, TL Parsons, JB Plotkin
Genetics 187 (4), 1139-1152, 2011
Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses
MB Schulte, JA Draghi, JB Plotkin, R Andino
Elife 4, e03753, 2015
Robustness to noise in gene expression evolves despite epistatic constraints in a model of gene networks
J Draghi, M Whitlock
Evolution 69 (9), 2345-2358, 2015
In evolution, the sum is less than its parts
S Kryazhimskiy, JA Draghi, JB Plotkin
science 332 (6034), 1160-1161, 2011
High-throughput analysis of growth differences among phage strains
PE Turner, JA Draghi, R Wilpiszeski
Journal of microbiological methods 88 (1), 117-121, 2012
Hidden diversity sparks adaptation
JA Draghi, JB Plotkin
Nature 474 (7349), 45-46, 2011
Links between evolutionary processes and phenotypic robustness in microbes
J Draghi
Seminars in cell & developmental biology 88, 46-53, 2019
Overdominance interacts with linkage to determine the rate of adaptation to a new optimum
J Draghi, MC Whitlock
Journal of evolutionary biology 28 (1), 95-104, 2015
Existing host range mutations constrain further emergence of RNA viruses
L Zhao, M Seth-Pasricha, D Stemate, A Crespo-Bellido, J Gagnon, ...
Journal of virology 93 (4), e01385-18, 2019
Developmental noise and ecological opportunity across space can release constraints on the evolution of plasticity
J Draghi
Evolution & development, e12305, 2019
Evolvability costs of niche expansion
LM Bono, JA Draghi, PE Turner
Trends in Genetics, 2019
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