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Dr. Jan van Riggelen
Dr. Jan van Riggelen
Penn State University
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Cited by
Cited by
Year
MYC as a regulator of ribosome biogenesis and protein synthesis
J Van Riggelen, A Yetil, DW Felsher
Nature Reviews Cancer 10 (4), 301-309, 2010
9462010
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
CH Wu, J Van Riggelen, A Yetil, AC Fan, P Bachireddy, DW Felsher
Proceedings of the National Academy of Sciences 104 (32), 13028-13033, 2007
4682007
Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch
S Giuriato, S Ryeom, AC Fan, P Bachireddy, RC Lynch, MJ Rioth, ...
Proceedings of the National Academy of Sciences 103 (44), 16266-16271, 2006
1902006
MYC—master regulator of the cancer epigenome and transcriptome
CJ Poole, J Van Riggelen
Genes 8 (5), 142, 2017
1432017
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance
J Van Riggelen, J Müller, T Otto, V Beuger, A Yetil, PS Choi, C Kosan, ...
Genes & development 24 (12), 1281-1294, 2010
1362010
High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation
AR Wu, TLA Kawahara, NA Rapicavoli, J Van Riggelen, EH Shroff, L Xu, ...
Lab on a Chip 12 (12), 2190-2198, 2012
802012
DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma
CJ Poole, W Zheng, A Lodh, A Yevtodiyenko, D Liefwalker, H Li, ...
Oncotarget 8 (44), 76898, 2017
572017
Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation
Y Cai, G Zhu, S Liu, Z Pan, M Quintero, CJ Poole, C Lu, H Zhu, B Islam, ...
Cell Discovery 5 (1), 7, 2019
502019
Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction
PS Choi, J Van Riggelen, AJ Gentles, P Bachireddy, K Rakhra, SJ Adam, ...
Proceedings of the National Academy of Sciences 108 (42), 17432-17437, 2011
502011
Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells
A Bachmann, B Hanke, R Zawatzky, U Soto, J Van Riggelen, ...
Journal of virology 76 (1), 280-291, 2002
412002
Myc and a Cdk2 senescence switch
J Van Riggelen, DW Felsher
Nature Cell Biology 12 (1), 7-9, 2010
352010
Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells
J Van Riggelen, G Buchwalter, U Soto, JDC Arce, H Zur Hausen, ...
Journal of Biological Chemistry 280 (5), 3286-3294, 2005
352005
MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy) methylation and gene expression to maintain a neoplastic phenotype in T-ALL
CJ Poole, A Lodh, JH Choi, J Van Riggelen
Epigenetics & chromatin 12, 1-20, 2019
312019
p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia
A Yetil, B Anchang, AM Gouw, SJ Adam, T Zabuawala, R Parameswaran, ...
Oncotarget 6 (6), 3563, 2015
282015
Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity
A Alptekin, B Ye, Y Yu, CJ Poole, J van Riggelen, Y Zha, HF Ding
Oncogene 38 (50), 7504-7520, 2019
242019
Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition
CJ Poole, W Zheng, H Lee, D Young, A Lodh, A Chadli, J Van Riggelen
Cancers 10 (11), 448, 2018
222018
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome
T Hu, Q Wu, Y Chong, H Qin, CJ Poole, J Van Riggelen, M Ren, ...
Leukemia 32 (11), 2363-2373, 2018
212018
Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells
JDC Arce, U Soto, J Van Riggelen, E Schwarz, H Zur Hausen, F Rösl
Journal of Biological Chemistry 279 (44), 45408-45416, 2004
172004
TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas
J Müller, B Samans, J Van Riggelen, G Fagà, R Peh KN, CL Wei, H Müller, ...
Cell Cycle 9 (23), 4622-4626, 2010
92010
Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells
MY Liu, JD Klement, CJ Langan, J van Riggelen, K Liu
Cellular immunology 366, 104397, 2021
72021
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