Lyn Jones
Lyn Jones
Dana-Farber Cancer Institute
Verified email at - Homepage
Cited by
Cited by
Developing irreversible inhibitors of the protein kinase cysteinome
Q Liu, Y Sabnis, Z Zhao, T Zhang, SJ Buhrlage, LH Jones, NS Gray
Chemistry & biology 20 (2), 146-159, 2013
Modern advances in heterocyclic chemistry in drug discovery
AP Taylor, RP Robinson, YM Fobian, DC Blakemore, LH Jones, O Fadeyi
Organic & biomolecular chemistry 14 (28), 6611-6637, 2016
Squaramides: physical properties, synthesis and applications
RI Storer, C Aciro, LH Jones
Chemical Society Reviews 40 (5), 2330-2346, 2011
Target validation using chemical probes
ME Bunnage, ELP Chekler, LH Jones
Nature chemical biology 9 (4), 195-199, 2013
Sulfonyl fluorides as privileged warheads in chemical biology
A Narayanan, LH Jones
Chemical science 6 (5), 2650-2659, 2015
Antibody catalysis of the oxidation of water
P Wentworth Jr, LH Jones, AD Wentworth, X Zhu, NA Larsen, IA Wilson, ...
Science 293 (5536), 1806-1811, 2001
Broad-spectrum kinase profiling in live cells with lysine-targeted sulfonyl fluoride probes
Q Zhao, X Ouyang, X Wan, KS Gajiwala, JC Kath, LH Jones, ...
Journal of the American Chemical Society 139 (2), 680-685, 2017
Antibodies have the intrinsic capacity to destroy antigens
AD Wentworth, LH Jones, P Wentworth Jr, KD Janda, RA Lerner
Proceedings of the National Academy of Sciences 97 (20), 10930-10935, 2000
Applications of chemogenomic library screening in drug discovery
LH Jones, ME Bunnage
Nature reviews Drug discovery 16 (4), 285-296, 2017
Physicochemical drug properties associated with in vivo toxicological outcomes: a review
DA Price, J Blagg, L Jones, N Greene, T Wager
Expert opinion on drug metabolism & toxicology 5 (8), 921-931, 2009
Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes
EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne Jr, CA Menard, ...
ACS Chemical Biology 10 (4), 1094-1098, 2015
Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition
JB Telliez, ME Dowty, LU Wang, J Jussif, T Lin, L Li, E Moy, P Balbo, W Li, ...
ACS chemical biology 11 (12), 3442-3451, 2016
Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action
P Targett-Adams, EJS Graham, J Middleton, A Palmer, SM Shaw, ...
Journal of virology 85 (13), 6353-6368, 2011
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay
J Hall, A Brault, F Vincent, S Weng, H Wang, D Dumlao, A Aulabaugh, ...
PLoS One 12 (9), e0184843, 2017
Oxaziridine-mediated amination of primary amines: Scope and application to a one-pot pyrazole synthesis
A Armstrong, LH Jones, JD Knight, RD Kelsey
Organic Letters 7 (4), 713-716, 2005
Recent advances in the molecular design of synthetic vaccines
LH Jones
Nature chemistry 7 (12), 952-960, 2015
Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery
DM Beal, LH Jones
Angewandte Chemie International Edition 51 (26), 6320-6326, 2012
Labeling preferences of diazirines with protein biomolecules
AV West, G Muncipinto, HY Wu, AC Huang, MT Labenski, LH Jones, ...
Journal of the American Chemical Society 143 (17), 6691-6700, 2021
Know your target, know your molecule
ME Bunnage, AM Gilbert, LH Jones, EC Hett
Nature chemical biology 11 (6), 368-372, 2015
Emerging utility of fluorosulfate chemical probes
LH Jones
ACS Medicinal Chemistry Letters 9 (7), 584-586, 2018
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