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Steven R. Hall
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Antitumor activity of abnormal cannabidiol and its analog O-1602 in taxol-resistant preclinical models of breast cancer
A Tomko, L O’Leary, H Trask, JC Achenbach, SR Hall, KB Goralski, ...
Frontiers in pharmacology 10, 1124, 2019
442019
Small molecule drug discovery for neglected tropical snakebite
RH Clare, SR Hall, RN Patel, NR Casewell
Trends in pharmacological sciences 42 (5), 340-353, 2021
392021
Jadomycin breast cancer cytotoxicity is mediated by a copper‐dependent, reactive oxygen species–inducing mechanism
SR Hall, HL Blundon, MA Ladda, AW Robertson, CF Martinez‐Farina, ...
Pharmacology Research & Perspectives 3 (2), e00110, 2015
392015
Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells
ME Issa, SR Hall, SN Dupuis, CL Graham, DL Jakeman, KB Goralski
Anti-Cancer Drugs 25 (3), 255-269, 2014
372014
Jadomycins inhibit type II topoisomerases and promote DNA damage and apoptosis in multidrug-resistant triple-negative breast cancer cells
SR Hall, J Toulany, LG Bennett, CF Martinez-Farina, AW Robertson, ...
Journal of Pharmacology and Experimental Therapeutics 363 (2), 196-210, 2017
292017
Decitabine response in breast cancer requires efficient drug processing and is not limited by multidrug resistance
ML Dahn, BM Cruickshank, AJ Jackson, C Dean, RW Holloway, SR Hall, ...
Molecular Cancer Therapeutics 19 (5), 1110-1122, 2020
202020
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus
SK Menzies, RH Clare, C Xie, A Westhorpe, SR Hall, RJ Edge, J Alsolaiss, ...
Toxicon: X 14, 100118, 2022
152022
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms
SR Hall, SA Rasmussen, E Crittenden, CA Dawson, KE Bartlett, ...
Nature communications 14 (1), 7812, 2023
142023
Post Polyketide Synthase Carbon–Carbon Bond Formation in Type-II PKS-Derived Natural Products from Streptomyces venezuelae
AW Robertson, JM MacLeod, LW MacIntyre, SM Forget, SR Hall, ...
The Journal of Organic Chemistry 83 (4), 1876-1890, 2018
122018
Exploring the utility of recombinant snake venom serine protease toxins as immunogens for generating experimental snakebite antivenoms
N Alomran, P Blundell, J Alsolaiss, E Crittenden, S Ainsworth, CA Dawson, ...
Toxins 14 (7), 443, 2022
102022
Two snakebite antivenoms have potential to reduce Eswatini’s dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing
SK Menzies, T Litschka-Koen, RJ Edge, J Alsolaiss, E Crittenden, SR Hall, ...
PLoS neglected tropical diseases 16 (9), e0010496, 2022
72022
Isolation of a jadomycin incorporating l-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast …
SM Forget, AW Robertson, SR Hall, JM MacLeod, DP Overy, RG Kerr, ...
The Journal of Antibiotics 71 (8), 722-730, 2018
72018
Physiological constraints dictate toxin spatial heterogeneity in snake venom glands
TD Kazandjian, BR Hamilton, SD Robinson, SR Hall, KE Bartlett, ...
BMC biology 20 (1), 148, 2022
52022
Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition
SK Menzies, CA Dawson, E Crittenden, RJ Edge, SR Hall, J Alsolaiss, ...
Scientific Reports 12 (1), 11328, 2022
42022
Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom
S Ahmadi, ST Pachis, K Kalogeropoulos, F McGeoghan, V Canbay, ...
Toxicon 220, 106955, 2022
32022
Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models
BT McKeown, NJ Relja, SR Hall, S Gebremeskel, JM MacLeod, ...
Canadian Journal of Physiology and Pharmacology 100 (11), 1065-1076, 2022
32022
The anticancer activity and mechanisms of action of jadomycins in multidrug resistant human breast cancer cells
SR Hall
32018
Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL
W Laprade, KE Bartlett, CR Christensen, TD Kazandjian, RN Patel, ...
Scientific Reports 13 (1), 21662, 2023
22023
ZATT, TDP2, and SUMO2: breaking the tie that binds TOP2 to DNA
SR Hall, KB Goralski
Translational Cancer Research 7 (Suppl 4), 2018
22018
The Synthesis and Molecular Structure of 1-(3,4-Dihydroxyphenethyl)-3-hydroxy-2-methylpyridin-4(1H)-one Hydrochloride Methanol Solvate
SR Hall, R Roy, DT McLaughlin, KJ Sullivan, LRC Barclay, CM Vogels, ...
Crystals 3 (2), 333-338, 2013
22013
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Articles 1–20