A Structural Model of the Staphylococcus aureus ClfA–Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics VK Ganesh, JJ Rivera, E Smeds, YP Ko, MG Bowden, ER Wann, ... PLoS pathogens 4 (11), e1000226, 2008 | 180 | 2008 |
Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway M Kang, YP Ko, X Liang, CL Ross, Q Liu, BE Murray, M Höök Journal of biological chemistry 288 (28), 20520-20531, 2013 | 179 | 2013 |
Phagocytosis Escape by a Staphylococcus aureus Protein That Connects Complement and Coagulation Proteins at the Bacterial Surface YP Ko, A Kuipers, CM Freitag, I Jongerius, E Medina, WJ van Rooijen, ... PLoS pathogens 9 (12), e1003816, 2013 | 161 | 2013 |
The matrilins–adaptor proteins in the extracellular matrix R Wagener, HWA Ehlen, YP Ko, B Kobbe, HH Mann, G Sengle, ... FEBS letters 579 (15), 3323-3329, 2005 | 137 | 2005 |
Tumor-associated antigen L6 and the invasion of human lung cancer cells YR Kao, JY Shih, WC Wen, YP Ko, BM Chen, YL Chan, YW Chu, ... Clinical cancer research 9 (7), 2807-2816, 2003 | 100 | 2003 |
Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense JM Prasad, OV Gorkun, H Raghu, S Thornton, ES Mullins, JS Palumbo, ... Blood, The Journal of the American Society of Hematology 126 (17), 2047-2058, 2015 | 97 | 2015 |
CD13 (aminopeptidase N) can associate with tumor‐associated antigen L6 and enhance the motility of human lung cancer cells YW Chang, SC Chen, EC Cheng, YP Ko, YC Lin, YR Kao, YG Tsay, ... International journal of cancer 116 (2), 243-252, 2005 | 94 | 2005 |
Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice C Nicolae, YP Ko, N Miosge, A Niehoff, D Studer, L Enggist, EB Hunziker, ... Journal of biological chemistry 282 (30), 22163-22175, 2007 | 91 | 2007 |
Fibrinogen is at the interface of host defense and pathogen virulence in Staphylococcus aureus infection YP Ko, MJ Flick Seminars in thrombosis and hemostasis, 408-421, 2016 | 88 | 2016 |
Matrilin-3 is dispensable for mouse skeletal growth and development Y Ko, B Kobbe, C Nicolae, N Miosge, M Paulsson, R Wagener, A Aszódi Molecular and cellular biology 24 (4), 1691-1699, 2004 | 82 | 2004 |
The Staphylococcus aureus polysaccharide capsule and Efb-dependent fibrinogen shield act in concert to protect against phagocytosis A Kuipers, DAC Stapels, LT Weerwind, YP Ko, M Ruyken, JC Lee, ... Microbiology 162 (7), 1185-1194, 2016 | 74 | 2016 |
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence YP Ko, X Liang, CW Smith, JL Degen, M Höök Journal of Biological Chemistry 286 (11), 9865-9874, 2011 | 68 | 2011 |
Induced pluripotent stem cell-derived vascular smooth muscle cells: methods and application BC Dash, Z Jiang, C Suh, Y Qyang Biochemical Journal 465 (2), 185-194, 2015 | 60 | 2015 |
The Complex Fibrinogen Interactions of the Staphylococcus aureus Coagulases S Thomas, W Liu, S Arora, V Ganesh, YP Ko, M Höök Frontiers in Cellular and Infection Microbiology 9, 106, 2019 | 46 | 2019 |
Coagulase and Efb of Staphylococcus aureus have a common fibrinogen binding motif YP Ko, M Kang, VK Ganesh, D Ravirajan, B Li, M Höök MBio 7 (1), 10.1128/mbio. 01885-15, 2016 | 41 | 2016 |
Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterparts YP Ko, B Kobbe, M Paulsson, R Wagener Biochemical Journal 386 (2), 367-379, 2005 | 31 | 2005 |
Matrilin-1 is essential for zebrafish development by facilitating collagen II secretion CD Neacsu, YP Ko, A Tagariello, KR Karlsen, WF Neiss, M Paulsson, ... Journal of Biological Chemistry 289 (3), 1505-1518, 2014 | 18 | 2014 |
A simple method for the production of recombinant proteins from mammalian cells CH Wu, WR Balasubramanian, YP Ko, G Hsu, SE Chang, ZM Prijovich, ... Biotechnology and applied biochemistry 40 (2), 167-172, 2004 | 18 | 2004 |
Oral administration of the complement factor D inhibitor danicopan (ALXN2040) in preclinical studies demonstrates high and sustained drug concentrations in posterior ocular … D Boyer, J Rivera, YP Ko, SD Podos, M Cartwright, X Gao, J Wiles, ... Investigative Ophthalmology & Visual Science 62 (8), 187-187, 2021 | 7 | 2021 |
Crystal structure of staphylococcus aureus clumping factor a in complex with fibrinogen derived peptide and uses thereof M Hook, YP Ko, E Smeds, VK Ganesh US Patent App. 13/605,567, 2013 | 7 | 2013 |