Alexandre Harlé
Alexandre Harlé
CNRS UMR 7039 CRAN, Université de Lorraine - Service de Biopathologie, Institut de Cancérologie de
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Dihydropyrimidine dehydrogenase (DPD) deficiency screening and securing of fluoropyrimidine-based chemotherapies: update and recommendations of the French GPCO-Unicancer and …
MA Loriot, J Ciccolini, F Thomas, C Barin-Le-Guellec, B Royer, G Milano, ...
Bulletin du cancer 105 (4), 397-407, 2018
SMAD4 and the TGFβ pathway in patients with pancreatic ductal adenocarcinoma
J Dardare, A Witz, JL Merlin, P Gilson, A Harlé
International journal of molecular sciences 21 (10), 3534, 2020
Detection of BRAF Mutations Using a Fully Automated Platform and Comparison with High Resolution Melting, Real-Time Allele Specific Amplification …
A Harlé, J Salleron, C Franczak, C Dubois, P Filhine-Tressarieu, A Leroux, ...
PLoS One 11 (4), e0153576, 2016
Representative sequencing: unbiased sampling of solid tumor tissue
K Litchfield, S Stanislaw, L Spain, LL Gallegos, A Rowan, D Schnidrig, ...
Cell reports 31 (5), 107550, 2020
Comparison of COBAS 4800 KRAS, TaqMan PCR and high resolution melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal …
A Harlé, B Busser, M Rouyer, V Harter, P Genin, A Leroux, JL Merlin
Virchows Archiv 462 (3), 329-335, 2013
Analysis of PIK3CA exon 9 and 20 mutations in breast cancers using PCR-HRM and PCR-ARMS: correlation with clinicopathological criteria
A Harle, M Lion, N Lozano, M Husson, V Harter, P Genin, JL Merlin
Oncology reports 29 (3), 1043-1052, 2013
Optimization of routine KRAS mutation PCR‐based testing procedure for rational individualized first‐line‐targeted therapy selection in metastatic colorectal cancer
AS Chretien, A Harle, M Meyer‐Lefebvre, M Rouyer, M Husson, ...
Cancer medicine 2 (1), 11-20, 2013
Technical considerations for circulating tumor DNA detection in oncology
C Franczak, P Filhine-Tresarrieu, P Gilson, JL Merlin, L Au, A Harlé
Expert Review of Molecular Diagnostics 19 (2), 121-135, 2019
Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers
P Gilson, J Levy, M Rouyer, J Demange, M Husson, C Bonnet, J Salleron, ...
Scientific reports 10 (1), 1-10, 2020
Rare RAS mutations in metastatic colorectal cancer detected during routine RAS genotyping using next generation sequencing
A Harlé, P Filhine-Tresarrieu, M Husson, R Boidot, M Rouyer, C Dubois, ...
Targeted oncology 11 (3), 363-370, 2016
Detection of microsatellite instability: state of the art and future applications in circulating tumour DNA (ctDNA)
P Gilson, JL Merlin, A Harlé
Cancers 13 (7), 1491, 2021
Evaluation and validation of HPV real-time PCR assay for the detection of HPV DNA in oral cytobrush and FFPE samples
A Harlé, J Guillet, J Thomas, X Sastre-Garau, M Rouyer, C Ramacci, ...
Scientific reports 8 (1), 1-6, 2018
Expression and activation of P38 MAP kinase in invasive ductal breast cancers: correlation with expression of the estrogen receptor, HER2 and downstream signaling …
JL Merlin, A Harlé, M Lion, C Ramacci, A Leroux
Oncology reports 30 (4), 1943-1948, 2013
Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential …
S Chen, E Cavazza, C Barlier, J Salleron, P Filhine‑Tresarrieu, C Gavoille, ...
Oncology Letters 12 (5), 3264-3272, 2016
Emerging roles of DDB2 in cancer
P Gilson, G Drouot, A Witz, JL Merlin, P Becuwe, A Harlé
International Journal of Molecular Sciences 20 (20), 5168, 2019
Dépistage du déficit en dihydropyrimidine déshydrogénase (DPD) et sécurisation des chimiothérapies à base de fluoropyrimidines: mise au point et recommandations nationales du …
MA Loriot, J Ciccolini, F Thomas, C Barin-Le-Guellec, B Royer, G Milano, ...
Bulletin du Cancer 105 (4), 397-407, 2018
HPV insertional pattern as a personalized tumor marker for the optimized tumor diagnosis and follow-up of patients with HPV-associated carcinomas: a case report
A Harlé, J Guillet, J Thomas, J Demange, G Dolivet, D Peiffert, A Leroux, ...
BMC cancer 19 (1), 1-8, 2019
Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated …
P Gilson, C Franczak, L Dubouis, M Husson, M Rouyer, J Demange, ...
PLoS One 14 (7), e0219204, 2019
Integrated routine workflow using next-generation sequencing and a fully-automated platform for the detection of KRAS, NRAS and BRAF mutations in formalin …
C Franczak, L Dubouis, P Gilson, M Husson, M Rouyer, J Demange, ...
PLoS One 14 (2), e0212801, 2019
Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
A Harlé, J Salleron, G Perkins, C Pilati, H Blons, P Laurent-Puig, JL Merlin
British Journal of Cancer 113 (4), 680-685, 2015
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