| Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma YT Tai, PA Mayes, C Acharya, MY Zhong, M Cea, A Cagnetta, J Craigen, ... Blood, The Journal of the American Society of Hematology 123 (20), 3128-3138, 2014 | 437 | 2014 |
| CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications YT Tai, Y Landesman, C Acharya, Y Calle, MY Zhong, M Cea, ... Leukemia 28 (1), 155-165, 2014 | 309 | 2014 |
| APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment YT Tai, C Acharya, G An, M Moschetta, MY Zhong, X Feng, M Cea, ... Blood, The Journal of the American Society of Hematology 127 (25), 3225-3236, 2016 | 302 | 2016 |
| Fasting-mimicking diet and hormone therapy induce breast cancer regression I Caffa, V Spagnolo, C Vernieri, F Valdemarin, P Becherini, M Wei, ... Nature 583 (7817), 620-624, 2020 | 229 | 2020 |
| Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE S Bruzzone, F Fruscione, S Morando, T Ferrando, A Poggi, A Garuti, ... PloS one 4 (11), e7897, 2009 | 203 | 2009 |
| Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma YT Tai, BY Chang, SY Kong, M Fulciniti, G Yang, Y Calle, Y Hu, J Lin, ... Blood, The Journal of the American Society of Hematology 120 (9), 1877-1887, 2012 | 198 | 2012 |
| The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses I Bauer, A Grozio, D Lasigliè, G Basile, L Sturla, M Magnone, G Sociali, ... Journal of Biological Chemistry 287 (49), 40924-40937, 2012 | 184 | 2012 |
| Carfilzomib with cyclophosphamide and dexamethasone or lenalidomide and dexamethasone plus autologous transplantation or carfilzomib plus lenalidomide and dexamethasone … F Gay, P Musto, D Rota-Scalabrini, L Bertamini, A Belotti, M Galli, ... The Lancet Oncology 22 (12), 1705-1720, 2021 | 166 | 2021 |
| Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition M Cea, A Cagnetta, M Fulciniti, YT Tai, T Hideshima, D Chauhan, ... Blood, The Journal of the American Society of Hematology 120 (17), 3519-3529, 2012 | 153 | 2012 |
| CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal-transition-like transcriptional activation AM Roccaro, Y Mishima, A Sacco, M Moschetta, YT Tai, J Shi, Y Zhang, ... Cell reports 12 (4), 622-635, 2015 | 136 | 2015 |
| Regulation and function of extracellular nicotinamide phosphoribosyltransferase/visfatin F Carbone, L Liberale, A Bonaventura, A Vecchiè, M Casula, M Cea, ... Comprehensive Physiology 7 (2), 603-621, 2011 | 109 | 2011 |
| The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival H Ohguchi, T Hideshima, MK Bhasin, GT Gorgun, L Santo, M Cea, ... Nature communications 7 (1), 10258, 2016 | 105 | 2016 |
| Nutrients in the Prevention of Alzheimer’s Disease AL Cremonini, I Caffa, M Cea, A Nencioni, P Odetti, F Monacelli Oxidative medicine and cellular longevity 2019, 2019 | 103 | 2019 |
| Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells M Cea, A Cagnetta, S Adamia, C Acharya, YT Tai, M Fulciniti, H Ohguchi, ... Blood, The Journal of the American Society of Hematology 127 (9), 1138-1150, 2016 | 101 | 2016 |
| Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors, and DNA repair F Piacente, I Caffa, S Ravera, G Sociali, M Passalacqua, VG Vellone, ... Cancer research 77 (14), 3857-3869, 2017 | 98 | 2017 |
| Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity A Cagnetta, M Cea, T Calimeri, C Acharya, M Fulciniti, YT Tai, ... Blood, The Journal of the American Society of Hematology 122 (7), 1243-1255, 2013 | 97 | 2013 |
| Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma E Taiana, V Favasuli, D Ronchetti, K Todoerti, F Pelizzoni, M Manzoni, ... Leukemia 34 (1), 234-244, 2020 | 95 | 2020 |
| Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition I Caffa, V D'Agostino, P Damonte, D Soncini, M Cea, F Monacelli, P Odetti, ... Oncotarget 6 (14), 11820, 2015 | 94 | 2015 |
| Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells M Cea, D Soncini, F Fruscione, L Raffaghello, A Garuti, L Emionite, ... PloS one 6 (7), e22739, 2011 | 87 | 2011 |
| Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity D Soncini, I Caffa, G Zoppoli, M Cea, A Cagnetta, M Passalacqua, ... Journal of Biological Chemistry 289 (49), 34189-34204, 2014 | 75 | 2014 |
