Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum T Triglia, JGT Menting, C Wilson, AF Cowman Proceedings of the National Academy of Sciences 94 (25), 13944-13949, 1997 | 501 | 1997 |
Cloning and expression of cytochrome P450 genes controlling flower colour TA Holton, F Brugliera, DR Lester, Y Tanaka, CD Hyland, JGT Menting, ... Nature 366 (6452), 276-279, 1993 | 478 | 1993 |
How insulin engages its primary binding site on the insulin receptor JG Menting, J Whittaker, MB Margetts, LJ Whittaker, GKW Kong, BJ Smith, ... Nature 493 (7431), 241-245, 2013 | 471 | 2013 |
Thyroxine transport in choroid plexus. PW Dickson, AR Aldred, JG Menting, PD Marley, WH Sawyer, G Schreiber Journal of Biological Chemistry 262 (29), 13907-13915, 1987 | 202 | 1987 |
Protective hinge in insulin opens to enable its receptor engagement JG Menting, Y Yang, SJ Chan, NB Phillips, BJ Smith, J Whittaker, ... Proceedings of the National Academy of Sciences 111 (33), E3395-E3404, 2014 | 176 | 2014 |
Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists BJ Smith, K Huang, G Kong, SJ Chan, S Nakagawa, JG Menting, SQ Hu, ... Proceedings of the National Academy of Sciences 107 (15), 6771-6776, 2010 | 123 | 2010 |
How ligand binds to the type 1 insulin-like growth factor receptor Y Xu, GKW Kong, JG Menting, MB Margetts, CA Delaine, LM Jenkin, ... Nature communications 9 (1), 821, 2018 | 114 | 2018 |
The signalling conformation of the insulin receptor ectodomain F Weis, JG Menting, MB Margetts, SJ Chan, Y Xu, N Tennagels, ... Nature communications 9 (1), 4420, 2018 | 107 | 2018 |
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ... Nature structural & molecular biology 23 (10), 916-920, 2016 | 88 | 2016 |
The insulin receptor changes conformation in unforeseen ways on ligand binding: sharpening the picture of insulin receptor activation CW Ward, JG Menting, MC Lawrence Bioessays 35 (11), 945-954, 2013 | 88 | 2013 |
Characterization of flavonoid 3 [prime], 5 [prime]-hydroxylase in microsomal membrane fraction of Petunia hybrida flowers JGT Menting, RK Scopes, TW Stevenson Plant Physiology 106 (2), 633-642, 1994 | 72 | 1994 |
The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum JGT Menting, L Tilley, LW Deady, K Ng, RJ Simpson, AF Cowman, ... Molecular and biochemical parasitology 88 (1-2), 215-224, 1997 | 67 | 1997 |
Structural congruency of ligand binding to the insulin and insulin/type 1 insulin-like growth factor hybrid receptors JG Menting, CF Lawrence, GKW Kong, MB Margetts, CW Ward, ... Structure 23 (7), 1271-1282, 2015 | 63 | 2015 |
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ... Nature structural & molecular biology 27 (7), 615-624, 2020 | 48* | 2020 |
Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding … AE Whitten, BJ Smith, JG Menting, MB Margetts, NM McKern, GO Lovrecz, ... Journal of molecular biology 394 (5), 878-892, 2009 | 42 | 2009 |
Insulin mimetic peptide disrupts the primary binding site of the insulin receptor CF Lawrence, MB Margetts, JG Menting, NA Smith, BJ Smith, CW Ward, ... Journal of Biological Chemistry 291 (30), 15473-15481, 2016 | 36 | 2016 |
Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design V Pandyarajan, BJ Smith, NB Phillips, L Whittaker, GP Cox, ... Journal of Biological Chemistry 289 (50), 34709-34727, 2014 | 35 | 2014 |
Extending halogen-based medicinal chemistry to proteins K El Hage, V Pandyarajan, NB Phillips, BJ Smith, JG Menting, J Whittaker, ... Journal of Biological Chemistry 291 (53), 27023-27041, 2016 | 33 | 2016 |
Differences in epitope recognition, isotype and titer of antisera to Plasmodium falciparum merozoite surface protein 4 raised by different modes of DNA or protein immunization L Wang, JGT Menting, CG Black, A Stowers, DC Kaslow, SL Hoffman, ... Vaccine 19 (7-8), 816-824, 2000 | 33 | 2000 |
Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity B Van Lierop, SC Ong, A Belgi, C Delaine, S Andrikopoulos, NL Haworth, ... Scientific reports 7 (1), 17239, 2017 | 32 | 2017 |