| Antisense oligonucleotides: modifications and clinical trials VK Sharma, RK Sharma, SK Singh MedChemComm 5 (10), 1454-1471, 2014 | 228 | 2014 |
| Synthesis, utility and medicinal importance of 1, 2-& 1, 4-dihydropyridines VK Sharma, SK Singh RSC advances 7 (5), 2682-2732, 2017 | 156 | 2017 |
| Oligonucleotide therapeutics: chemistry, delivery and clinical progress VK Sharma, JK Watts Future medicinal chemistry 7 (16), 2221-2242, 2015 | 107 | 2015 |
| Nucleic acid therapeutics: basic concepts and recent developments VK Sharma, P Rungta, AK Prasad RSC Advances 4 (32), 16618-16631, 2014 | 86 | 2014 |
| Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs’ dystrophy J Hu, Z Rong, X Gong, Z Zhou, VK Sharma, C Xing, JK Watts, DR Corey, ... Human molecular genetics 27 (6), 1015-1026, 2018 | 64 | 2018 |
| Novel cluster and monomer-based GalNAc structures induce effective uptake of siRNAs in vitro and in vivo VK Sharma, MF Osborn, MR Hassler, D Echeverria, S Ly, EA Ulashchik, ... Bioconjugate chemistry 29 (7), 2478-2488, 2018 | 36 | 2018 |
| Synthesis and biological properties of triazole-linked locked nucleic acid VK Sharma, SK Singh, PM Krishnamurthy, JF Alterman, RA Haraszti, ... Chemical communications 53 (63), 8906-8909, 2017 | 36 | 2017 |
| Activation of frataxin protein expression by antisense oligonucleotides targeting the mutant expanded repeat L Li, X Shen, Z Liu, M Norrbom, TP Prakash, D O'Reilly, VK Sharma, ... nucleic acid therapeutics 28 (1), 23-33, 2018 | 35 | 2018 |
| Chemoenzymatic Convergent Synthesis of 2′-O,4′-C-Methyleneribonucleosides VK Sharma, M Kumar, CE Olsen, AK Prasad The Journal of organic chemistry 79 (13), 6336-6341, 2014 | 27 | 2014 |
| Locked nucleic acid gapmers and conjugates potently silence ADAM33, an asthma-associated metalloprotease with nuclear-localized mRNA HM Pendergraff, PM Krishnamurthy, AJ Debacker, MP Moazami, ... Molecular Therapy-Nucleic Acids 8, 158-168, 2017 | 25 | 2017 |
| Biocatalytic Deacylation Studies on Tetra-O-acyl-β-d-xylofuranosyl Nucleosides: Synthesis of xylo-LNA Monomers SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad The Journal of Organic Chemistry 76 (18), 7556-7562, 2011 | 19 | 2011 |
| Chemoenzymatic Synthesis of C-4′-Spiro-oxetanoribonucleosides VK Sharma, M Kumar, D Sharma, CE Olsen, AK Prasad The Journal of Organic Chemistry 79 (18), 8516-8521, 2014 | 16 | 2014 |
| Reactions of 1,2- & 1,4-dihydropyridines SK Singh, VK Sharma Curr Org Chem 18 (9), 1159-1207, 2014 | 16 | 2014 |
| Biocatalytic Separation of N-7/N-9 Guanine Nucleosides SK Singh, VK Sharma, CE Olsen, J Wengel, VS Parmar, AK Prasad The Journal of Organic Chemistry 75 (22), 7932-7935, 2010 | 14 | 2010 |
| Design and synthesis of LNA-based mercaptoacetamido-linked nucleoside dimers VK Sharma, SK Singh, K Bohra, V Khatri, CE Olsen, AK Prasad Nucleosides, Nucleotides and Nucleic Acids 32 (5), 256-272, 2013 | 13 | 2013 |
| Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing AJ Debacker, VK Sharma, P Meda Krishnamurthy, D O’Reilly, R Greenhill, ... Biochemistry 58 (6), 582-589, 2019 | 12 | 2019 |
| Chemo-enzymatic synthesis of bicyclic 3′-azido-and 3′-amino-nucleosides M Kumar, VK Sharma, CE Olsen, AK Prasad RSC Advances 4 (70), 37231-37235, 2014 | 11 | 2014 |
| Biocatalytic route to C-3′-azido/-hydroxy-C-4′-spiro-oxetanoribonucleosides M Kumar, VK Sharma, R Kumar, AK Prasad Carbohydrate research 417, 19-26, 2015 | 7 | 2015 |
| Synthesis of triazole-linked LNA-based non-ionic nucleoside dimers using Cu(I)-catalyzed ‘Click’ reaction SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad Curr. Org. Synth. 11 (5), 757-766, 2014 | 7 | 2014 |
| Dendrimers: A class of polymer in the nanotechnology for drug delivery SK Singh, VK Sharma Nanomedicine for Drug Delivery and Therapeutics, 373-409, 2013 | 7 | 2013 |
Jonathan K. WattsProfessor, RNA Therapeutics Institute, UMass Chan Medical SchoolVerified email at umassmed.edu
