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Grant W Brown
Grant W Brown
Verified email at utoronto.ca - Homepage
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Cited by
Year
Global mapping of the yeast genetic interaction network
AHY Tong, G Lesage, GD Bader, H Ding, H Xu, X Xin, J Young, GF Berriz, ...
science 303 (5659), 808-813, 2004
25492004
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map
SR Collins, KM Miller, NL Maas, A Roguev, J Fillingham, CS Chu, ...
Nature 446 (7137), 806-810, 2007
10242007
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
AB Parsons, RL Brost, H Ding, Z Li, C Zhang, B Sheikh, GW Brown, ...
Nature biotechnology 22 (1), 62-69, 2004
7602004
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress
JM Tkach, A Yimit, AY Lee, M Riffle, M Costanzo, D Jaschob, JA Hendry, ...
Nature cell biology 14 (9), 966-976, 2012
5642012
Regulation of chromosome replication
TJ Kelly, GW Brown
Annual review of biochemistry 69 (1), 829-880, 2000
5472000
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase
S Nagai, K Dubrana, M Tsai-Pflugfelder, MB Davidson, TM Roberts, ...
Science 322 (5901), 597-602, 2008
4942008
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
4822017
Unification of protein abundance datasets yields a quantitative Saccharomyces cerevisiae proteome
B Ho, A Baryshnikova, GW Brown
Cell systems 6 (2), 192-205. e3, 2018
4302018
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ...
Nature methods 7 (12), 1017-1024, 2010
4152010
A genetic map of the response to DNA damage in human cells
M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ...
Cell 182 (2), 481-496. e21, 2020
3702020
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage
M Chang, M Bellaoui, C Boone, GW Brown
Proceedings of the National Academy of Sciences 99 (26), 16934-16939, 2002
3562002
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
L Wu, CZ Bachrati, J Ou, C Xu, J Yin, M Chang, W Wang, L Li, GW Brown, ...
Proceedings of the National Academy of Sciences 103 (11), 4068-4073, 2006
3172006
The synthetic genetic interaction spectrum of essential genes
AP Davierwala, J Haynes, Z Li, RL Brost, MD Robinson, L Yu, ...
Nature genetics 37 (10), 1147-1152, 2005
2762005
Systematic analysis of complex genetic interactions
E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ...
Science 360 (6386), eaao1729, 2018
2722018
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
2662014
Identification of protein complexes required for efficient sister chromatid cohesion
ML Mayer, I Pot, M Chang, H Xu, V Aneliunas, T Kwok, R Newitt, ...
Molecular biology of the cell 15 (4), 1736-1745, 2004
2652004
Regulation of the replication initiator protein p65 cdc18 by CDK phosphorylation
PV Jallepalli, GW Brown, M Muzi-Falconi, D Tien, TJ Kelly
Genes & development 11 (21), 2767-2779, 1997
2341997
RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability
D Xu, R Guo, A Sobeck, CZ Bachrati, J Yang, T Enomoto, GW Brown, ...
Genes & development 22 (20), 2843-2855, 2008
2152008
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex
M Chang, M Bellaoui, C Zhang, R Desai, P Morozov, L Delgado‐Cruzata, ...
The EMBO journal 24 (11), 2024-2033, 2005
2012005
Exploiting DNA replication stress for cancer treatment
T Ubhi, GW Brown
Cancer research 79 (8), 1730-1739, 2019
1912019
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