Grant W Brown

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	All	Since 2016
Citations	11425	3818
h-index	48	35
i10-index	84	66

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Co-authors

Charles BooneProfessor, Donnelly Centre, University of TorontoVerified email at utoronto.ca
Michael ChangEuropean Research Institute for the Biology of AgeingVerified email at umcg.nl
Michael Costanzouniversity of torontoVerified email at utoronto.ca
Corey NislowProfessor, CRC Tier 1 in Translational Genomics, University of British ColumbiaVerified email at ubc.ca
Timothy R. HughesUniversity of TorontoVerified email at utoronto.ca
Jessica Vaisica, Ph.D.Graduate Student, University of TorontoVerified email at mail.utoronto.ca
Csanad Z. BachratiUniversity of LincolnVerified email at lincoln.ac.uk
Anastasia BaryshnikovaPrincipal Investigator, Calico Life SciencesVerified email at calicolabs.com
Chad MyersUniversity of MinnesotaVerified email at umn.edu
Guri Nina GiaeverAssociate Professor, Faculty of Pharmaceutical Sciences, University of British ColumbiaVerified email at UBC.ca
anne-claude gingrasLunenfeld-Tanenbaum Research Institute; University of TorontoVerified email at lunenfeld.ca
Zhaolei Zhang, ProfessorUniversity of Toronto, Donnelly Centre, Dept of Molecular Genetics, Dept of Computer ScienceVerified email at utoronto.ca
Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of MolecularVerified email at lunenfeld.ca
Taehyung KimUniversity of TorontoVerified email at utoronto.ca
Marcus SmolkaCornell UniversityVerified email at cornell.edu
Ridhdhi DesaiHarvard Medical School, Beth Israel Deaconess Medical CenterVerified email at bidmc.harvard.edu
KATSUHIKO SHIRAHIGEProfessor, Research Center for Epigenetic Disease, Institute for Molecular and Cellular BiosciencesVerified email at iam.u-tokyo.ac.jp
Nevan KroganUniversity of California-San FranciscoVerified email at ucsf.edu
Susan M. GasserFriedrich Miescher Institute for Biomedical ResearchVerified email at fmi.ch
Jason MoffatProfessor, University of TorontoVerified email at utoronto.ca

Grant W Brown

University of Toronto

Verified email at utoronto.ca - Homepage

DNA Replication Genomic Instability


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Global mapping of the yeast genetic interaction network AHY Tong, G Lesage, GD Bader, H Ding, H Xu, X Xin, J Young, GF Berriz, ... science 303 (5659), 808-813, 2004	2284	2004
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map SR Collins, KM Miller, NL Maas, A Roguev, J Fillingham, CS Chu, ... Nature 446 (7137), 806-810, 2007	920	2007
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways AB Parsons, RL Brost, H Ding, Z Li, C Zhang, B Sheikh, GW Brown, ... Nature biotechnology 22 (1), 62-69, 2004	675	2004
Regulation of chromosome replication TJ Kelly, GW Brown Annual review of biochemistry 69 (1), 829-880, 2000	498	2000
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase S Nagai, K Dubrana, M Tsai-Pflugfelder, MB Davidson, TM Roberts, ... Science 322 (5901), 597-602, 2008	407	2008
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress JM Tkach, A Yimit, AY Lee, M Riffle, M Costanzo, D Jaschob, JA Hendry, ... Nature cell biology 14 (9), 966-976, 2012	390	2012
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage M Chang, M Bellaoui, C Boone, GW Brown Proceedings of the National Academy of Sciences 99 (26), 16934-16939, 2002	323	2002
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ... Nature methods 7 (12), 1017-1024, 2010	315	2010
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates L Wu, CZ Bachrati, J Ou, C Xu, J Yin, M Chang, W Wang, L Li, GW Brown, ... Proceedings of the National Academy of Sciences 103 (11), 4068-4073, 2006	276	2006
The synthetic genetic interaction spectrum of essential genes AP Davierwala, J Haynes, Z Li, RL Brost, MD Robinson, L Yu, ... Nature genetics 37 (10), 1147-1152, 2005	244	2005
Identification of protein complexes required for efficient sister chromatid cohesion ML Mayer, I Pot, M Chang, H Xu, V Aneliunas, T Kwok, R Newitt, ... Molecular biology of the cell 15 (4), 1736-1745, 2004	236	2004
Regulation of the replication initiator protein p65 cdc18 by CDK phosphorylation PV Jallepalli, GW Brown, M Muzi-Falconi, D Tien, TJ Kelly Genes & Development 11 (21), 2767-2779, 1997	215	1997
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ... Nature communications 8 (1), 1-18, 2017	192	2017
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex M Chang, M Bellaoui, C Zhang, R Desai, P Morozov, L Delgado‐Cruzata, ... The EMBO journal 24 (11), 2024-2033, 2005	190	2005
Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RPS Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014	179	2014
RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability D Xu, R Guo, A Sobeck, CZ Bachrati, J Yang, T Enomoto, GW Brown, ... Genes & development 22 (20), 2843-2855, 2008	174	2008
Elg1 forms an alternative RFC complex important for DNA replication and genome integrity M Bellaoui, M Chang, J Ou, H Xu, C Boone, GW Brown The EMBO journal 22 (16), 4304-4313, 2003	168	2003
Unification of protein abundance datasets yields a quantitative Saccharomyces cerevisiae proteome B Ho, A Baryshnikova, GW Brown Cell systems 6 (2), 192-205. e3, 2018	153	2018
Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast GW Brown, TJ Kelly Journal of Biological Chemistry 273 (34), 22083-22090, 1998	151	1998
cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe MM Falconi, GW Brown, TJ Kelly Proceedings of the National Academy of Sciences 93 (4), 1566-1570, 1996	151	1996

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