|Cancer stem cells|
MF Clarke, AT Hass
Reviews in Cell Biology and Molecular Medicine, 2006
|Purification and unique properties of mammary epithelial stem cells|
J Stingl, P Eirew, I Ricketson, M Shackleton, F Vaillant, D Choi, HI Li, ...
Nature 439 (7079), 993, 2006
|The clonal and mutational evolution spectrum of primary triple-negative breast cancers|
SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ...
Nature 486 (7403), 395, 2012
|Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells|
RD Morin, MD O’Connor, M Griffith, F Kuchenbauer, A Delaney, ...
Genome research 18 (4), 610-621, 2008
|Cancer stem cells: an evolving concept|
LV Nguyen, R Vanner, P Dirks, CJ Eaves
Nature Reviews Cancer 12 (2), 133, 2012
|Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers|
HJ Sutherland, PM Lansdorp, DH Henkelman, AC Eaves, CJ Eaves
Proceedings of the National Academy of Sciences 87 (9), 3584-3588, 1990
|Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro|
HJ Sutherland, CJ Eaves, AC Eaves, W Dragowska, PM Lansdorp
Blood 74 (5), 1563-1570, 1989
|Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.|
G Sauvageau, U Thorsteinsdottir, CJ Eaves, HJ Lawrence, C Largman, ...
Genes & development 9 (14), 1753-1765, 1995
|Correction of sickle cell disease in transgenic mouse models by gene therapy|
R Pawliuk, KA Westerman, ME Fabry, E Payen, R Tighe, EE Bouhassira, ...
Science 294 (5550), 2368-2371, 2001
|Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines|
JS Greenberger, MA Sakakeeny, RK Humphries, CJ Eaves, RJ Eckner
Proceedings of the National Academy of Sciences 80 (10), 2931-2935, 1983
|Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells|
G Sauvageau, PM Lansdorp, CJ Eaves, DE Hogge, WH Dragowska, ...
Proceedings of the National Academy of Sciences 91 (25), 12223-12227, 1994
|Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia|
T Holyoake, X Jiang, C Eaves, A Eaves
Blood 94 (6), 2056-2064, 1999
|Cancer stem cell definitions and terminology: the devil is in the details|
P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ...
Nature Reviews Cancer 12 (11), 767, 2012
|Long-term propagation of distinct hematopoietic differentiation programs in vivo|
B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton, K Lyons, SJ Lee, ...
Cell stem cell 1 (2), 218-229, 2007
|Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic–scid …|
E Conneally, J Cashman, A Petzer, C Eaves
Proceedings of the National Academy of Sciences 94 (18), 9836-9841, 1997
|Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy.|
SJ Szilvassy, RK Humphries, PM Lansdorp, AC Eaves, CJ Eaves
Proceedings of the National Academy of Sciences 87 (22), 8736-8740, 1990
|Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin|
KG Leong, K Niessen, I Kulic, A Raouf, C Eaves, I Pollet, A Karsan
Journal of Experimental Medicine 204 (12), 2935-2948, 2007
|Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium|
AL Petzer, DE Hogge, PM Landsdorp, DS Reid, CJ Eaves
Proceedings of the National Academy of Sciences 93 (4), 1470-1474, 1996
|Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue|
J Stingl, CJ Eaves, I Zandieh, JT Emerman
Breast cancer research and treatment 67 (2), 93-109, 2001
|Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution|
P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ...
Nature 518 (7539), 422, 2015