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Christopher C. Mader
Christopher C. Mader
Flatiron Health
Verified email at flatiron.com
Title
Cited by
Cited by
Year
The Drug Repurposing Hub: a next-generation drug library and information resource
SM Corsello, JA Bittker, Z Liu, J Gould, P McCarren, JE Hirschman, ...
Nature medicine 23 (4), 405-408, 2017
8002017
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
Nature cancer 1 (2), 235-248, 2020
5062020
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ...
Journal of Cell Biology 186 (4), 571-587, 2009
4372009
An EGFR–Src–Arg–cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion
CC Mader, M Oser, MAO Magalhaes, JJ Bravo-Cordero, J Condeelis, ...
Cancer research 71 (5), 1730-1741, 2011
3402011
Immunomodulatory spherical nucleic acids
AF Radovic-Moreno, N Chernyak, CC Mader, S Nallagatla, RS Kang, ...
Proceedings of the National Academy of Sciences 112 (13), 3892-3897, 2015
2792015
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
GS Kinker, AC Greenwald, R Tal, Z Orlova, MS Cuoco, JM McFarland, ...
Nature genetics 52 (11), 1208-1218, 2020
2582020
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway
MAO Magalhaes, DR Larson, CC Mader, JJ Bravo-Cordero, H Gil-Henn, ...
Journal of Cell Biology 195 (5), 903-920, 2011
2462011
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia
M Oser, CC Mader, H Gil-Henn, M Magalhaes, JJ Bravo-Cordero, ...
Journal of cell science 123 (21), 3662-3673, 2010
1892010
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ...
Nucleic acids research 46 (D1), D558-D566, 2018
1682018
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
C Chung, CC Mader, JC Schmitz, J Atladottir, P Fitchev, ML Cornwell, ...
Laboratory investigation 91 (5), 732-743, 2011
1372011
Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion
S Lapetina, CC Mader, K Machida, BJ Mayer, AJ Koleske
Journal of cell biology 185 (3), 503-519, 2009
1202009
Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate
LR Giam, MD Massich, L Hao, L Shin Wong, CC Mader, CA Mirkin
Proceedings of the National Academy of Sciences 109 (12), 4377-4382, 2012
1102012
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells
BJ Rosenberg, H Gil-Henn, CC Mader, T Halo, T Yin, J Condeelis, ...
Molecular biology of the cell 28 (10), 1347-1360, 2017
472017
Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes
JE Hornick, CC Mader, EK Tribble, CC Bagne, KT Vaughan, SL Shaw, ...
Current biology 21 (7), 598-605, 2011
412011
Lessons learned from SARS-CoV-2 measurements in wastewater
ME Sharkey, N Kumar, AMA Mantero, KM Babler, MM Boone, ...
Science of The Total Environment 798, 149177, 2021
402021
Non-oncology drugs are a source of previously unappreciated anti-cancer activity
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
BioRxiv, 730119, 2019
352019
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
AF Radovic-Moreno, CC Mader, S Nallagatla, W Hasan, A Love, ...
US Patent 10,894,963, 2021
332021
Liposomal particles, methods of making same and uses thereof
CA Mirkin, ST Nguyen, RS Banga, N Chernyak, S Gryaznov, ...
US Patent 10,182,988, 2019
242019
Spherical nucleic acid-based constructs as immunoregulatory agents
S Gryaznov, CC Mader, AF Radovic-Moreno
232015
Probing cell shape regulation with patterned substratum: requirement of myosin II-mediated contractility
CC Mader, EH Hinchcliffe, Y Wang
Soft Matter 3 (3), 357-363, 2007
202007
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