L Patrick Schenck
L Patrick Schenck
Program Manager, Weston Family Foundation
Verified email at mcmaster.ca
Title
Cited by
Cited by
Year
Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction
N Thevaranjan, A Puchta, C Schulz, A Naidoo, JC Szamosi, ...
Cell host & microbe 21 (4), 455-466. e4, 2017
4862017
Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome
J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ...
Gastroenterology 139 (2), 542-552. e3, 2010
2012010
Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue
JA Cotton, JP Motta, LP Schenck, SA Hirota, PL Beck, AG Buret
PloS one 9 (10), e109087, 2014
572014
Composition and immunological significance of the upper respiratory tract microbiota
LP Schenck, MG Surette, DME Bowdish
FEBS letters 590 (21), 3705-3720, 2016
492016
Intrarectal instillation of Clostridium difficile toxin A triggers colonic inflammation and tissue damage: development of a novel and efficient mouse model of Clostridium …
SA Hirota, V Iablokov, SE Tulk, LP Schenck, H Becker, J Nguyen, ...
Infection and immunity 80 (12), 4474-4484, 2012
462012
Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis
S Krishnan, IE Prise, K Wemyss, LP Schenck, HM Bridgeman, FA McClure, ...
Proceedings of the National Academy of Sciences 115 (42), 10738-10743, 2018
402018
The P2Y 6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction
A Hansen, L Alston, SE Tulk, LP Schenck, ME Grassie, BF Alhassan, ...
PloS one 8 (11), e81491, 2013
362013
Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study
D Lamarche, J Johnstone, N Zytaruk, F Clarke, L Hand, D Loukov, ...
Respiratory research 19 (1), 1-12, 2018
322018
Gastrointestinal dysbiosis and the use of fecal microbial transplantation in Clostridium difficile infection
LP Schenck, PL Beck, JA MacDonald
World journal of gastrointestinal pathophysiology 6 (4), 169, 2015
222015
Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease
DT Reid, B McDonald, T Khalid, T Vo, LP Schenck, MG Surette, PL Beck, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (7 …, 2016
162016
Streptococcus pneumoniae colonization is required to alter the nasal microbiota in cigarette smoke-exposed mice
P Shen, FJ Whelan, LP Schenck, JJC McGrath, G Vanderstocken, ...
Infection and immunity 85 (10), e00434-17, 2017
112017
Attenuation of Clostridium difficile toxin‐induced damage to epithelial barrier by ecto‐5′‐nucleotidase (CD73) and adenosine receptor signaling
L Patrick Schenck, SA Hirota, CL Hirota, P Boasquevisque, SE Tulk, Y Li, ...
Neurogastroenterology & Motility 25 (6), e441-e453, 2013
112013
The Src kinase Fyn is protective in acute chemical‐induced colitis and promotes recovery from disease
F Lopes, A Wang, D Smyth, JL Reyes, A Doering, LP Schenck, P Beck, ...
Journal of leukocyte biology 97 (6), 1089-1099, 2015
62015
Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice
SA Hirota, A Ueno, SE Tulk, HM Becker, LP Schenck, MS Potentier, Y Li, ...
Mediators of inflammation 2016, 2016
22016
1000 Elucidating Intestinal Microbiota Components That Play a Protective or Deleterious Role During Clostridium difficile Infections
LP Schenck, SA Hirota, GD Armstrong, JA MacDonald, PL Beck
Gastroenterology 144 (5), S-185, 2013
12013
CD73-Mediated liberation of adenosine protects intestinal epithelial cells from C. difficile toxin-induced damage
LP Schenck, SA Hirota, MS Potentier, Y Li, GD Armstrong, PL Beck, ...
Gastroenterology 140 (5), S-498, 2011
12011
Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract
JJC McGrath, D Thayaparan, SP Cass, JP Mapletoft, PYF Zeng, ...
Mucosal Immunology, 1-10, 2021
2021
Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota
LP Schenck, JJC McGrath, D Lamarche, MR Stämpfli, DME Bowdish, ...
Msphere 5 (6), e00562-20, 2020
2020
Inhibition of Nasal and Systemic IgA Responses by Cigarette Smoke Exposure in Mice
J McGrath, D Thayaparan, S Cass, B Ly, R Heo, S Afkhami, J Koenig, ...
C63. MECHANISTIC STUDIES IN COPD, A5379-A5379, 2019
2019
The upper respiratory tract microbiota contributes to susceptibility to Streptococcus pneumoniae infections
LP Schenck
2019
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