L Patrick Schenck
L Patrick Schenck
Program Manager, Weston Family Foundation
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Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction
N Thevaranjan, A Puchta, C Schulz, A Naidoo, JC Szamosi, ...
Cell host & microbe 21 (4), 455-466. e4, 2017
Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome
J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ...
Gastroenterology 139 (2), 542-552. e3, 2010
Composition and immunological significance of the upper respiratory tract microbiota
LP Schenck, MG Surette, DME Bowdish
FEBS letters 590 (21), 3705-3720, 2016
Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis
S Krishnan, IE Prise, K Wemyss, LP Schenck, HM Bridgeman, FA McClure, ...
Proceedings of the National Academy of Sciences 115 (42), 10738-10743, 2018
Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue
JA Cotton, JP Motta, LP Schenck, SA Hirota, PL Beck, AG Buret
PloS one 9 (10), e109087, 2014
Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study
D Lamarche, J Johnstone, N Zytaruk, F Clarke, L Hand, D Loukov, ...
Respiratory Research 19, 1-12, 2018
The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction
A Hansen, L Alston, SE Tulk, LP Schenck, ME Grassie, BF Alhassan, ...
PloS one 8 (11), e81491, 2013
Intrarectal instillation of Clostridium difficile toxin A triggers colonic inflammation and tissue damage: development of a novel and efficient mouse model of Clostridium …
SA Hirota, V Iablokov, SE Tulk, LP Schenck, H Becker, J Nguyen, ...
Infection and immunity 80 (12), 4474-4484, 2012
Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease
DT Reid, B McDonald, T Khalid, T Vo, LP Schenck, MG Surette, PL Beck, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (7 …, 2016
Gastrointestinal dysbiosis and the use of fecal microbial transplantation in Clostridium difficile infection
LP Schenck, PL Beck, JA MacDonald
World journal of gastrointestinal pathophysiology 6 (4), 169, 2015
Streptococcus pneumoniae colonization is required to alter the nasal microbiota in cigarette smoke-exposed mice
P Shen, FJ Whelan, LP Schenck, JJC McGrath, G Vanderstocken, ...
Infection and immunity 85 (10), 10.1128/iai. 00434-17, 2017
Attenuation of Clostridium difficile toxin‐induced damage to epithelial barrier by ecto‐5′‐nucleotidase (CD73) and adenosine receptor signaling
L Patrick Schenck, SA Hirota, CL Hirota, P Boasquevisque, SE Tulk, Y Li, ...
Neurogastroenterology & Motility 25 (6), e441-e453, 2013
Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract
JJC McGrath, D Thayaparan, SP Cass, JP Mapletoft, PYF Zeng, ...
Mucosal Immunology 14 (5), 1067-1076, 2021
The Src kinase Fyn is protective in acute chemical-induced colitis and promotes recovery from disease
F Lopes, A Wang, D Smyth, JL Reyes, A Doering, LP Schenck, P Beck, ...
Journal of Leucocyte Biology 97 (6), 1089-1099, 2015
Nasal tissue extraction is essential for characterization of the murine upper respiratory tract microbiota
LP Schenck, JJC McGrath, D Lamarche, MR Stämpfli, DME Bowdish, ...
Msphere 5 (6), 10.1128/msphere. 00562-20, 2020
Exaggerated IL‐15 and Altered Expression of foxp3+ Cell‐Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice
SA Hirota, A Ueno, SE Tulk, HM Becker, LP Schenck, MS Potentier, Y Li, ...
Mediators of inflammation 2016 (1), 5637685, 2016
The impact of respiratory infections and probiotic use on the nasal microbiota of frail residents in long-term care homes
DME Bowdish, L Rossi, M Loeb, J Johnstone, LP Schenck, M Fontes, ...
ERJ Open Research 9 (5), 2023
1000 Elucidating Intestinal Microbiota Components That Play a Protective or Deleterious Role During Clostridium difficile Infections
LP Schenck, SA Hirota, GD Armstrong, JA MacDonald, PL Beck
Gastroenterology 5 (144), S-185, 2013
CD73-Mediated liberation of adenosine protects intestinal epithelial cells from C. difficile toxin-induced damage
LP Schenck, SA Hirota, MS Potentier, Y Li, GD Armstrong, PL Beck, ...
Gastroenterology 5 (140), S-498, 2011
Inhibition of Nasal and Systemic IgA Responses by Cigarette Smoke Exposure in Mice
J McGrath, D Thayaparan, S Cass, B Ly, R Heo, S Afkhami, J Koenig, ...
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