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Tarek A. Leil
Tarek A. Leil
Executive Director, Daiichi Sankyo, Inc.
Verified email at dsi.com
Title
Cited by
Cited by
Year
Cardiac myocyte-specific excision of the β1 integrin gene results in myocardial fibrosis and cardiac failure
SY Shai, AE Harpf, CJ Babbitt, MC Jordan, MC Fishbein, J Chen, ...
Circulation research 90 (4), 458-464, 2002
3322002
Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study
EA Raetz, MS Cairo, MJ Borowitz, SM Blaney, MD Krailo, TA Leil, JM Reid, ...
Journal of Clinical Oncology 26 (22), 3756, 2008
2502008
GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons
TA Leil, ZW Chen, CSS Chang, RW Olsen
Journal of Neuroscience 24 (50), 11429-11438, 2004
2142004
Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: selection of phase III trial dose
TA Leil, Y Feng, L Zhang, A Paccaly, P Mohan, M Pfister
CliniCal pharmaCology & TherapeuTiCs 88 (3), 375-382, 2010
1092010
Quantitative systems pharmacology can reduce attrition and improve productivity in pharmaceutical research and development
TA Leil, R Bertz
Frontiers in pharmacology 5, 101940, 2014
722014
GABAA receptor-associated protein regulates GABAA receptor cell-surface number in Xenopus laevis oocytes
ZW Chen, CSS Chang, TA Leil, R Olcese, RW Olsen
Molecular pharmacology 68 (1), 152-159, 2005
672005
C-terminal modification is required for GABARAP-mediated GABAA receptor trafficking
ZW Chen, CSS Chang, TA Leil, RW Olsen
Journal of Neuroscience 27 (25), 6655-6663, 2007
632007
Population pharmacokinetics of apixaban in subjects with nonvalvular atrial fibrillation
B Cirincione, K Kowalski, J Nielsen, A Roy, N Thanneer, W Byon, R Boyd, ...
CPT: pharmacometrics & systems pharmacology 7 (11), 728-738, 2018
622018
Genes regulated by learning in the hippocampus
TA Leil, A Ossadtchi, TE Nichols, RM Leahy, DJ Smith
Journal of neuroscience research 71 (6), 763-768, 2003
612003
Identification and characterization of genetic variation in the folylpolyglutamate synthase gene
TA Leil, C Endo, AA Adjei, GK Dy, OE Salavaggione, JR Reid, MM Ames, ...
Cancer research 67 (18), 8772-8782, 2007
572007
Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans
Y Lu, SC Griffen, DW Boulton, TA Leil
Frontiers in pharmacology 5, 274, 2014
562014
Finding new candidate genes for learning and memory
TA Leil, A Ossadtchi, JS Cortes, RM Leahy, DJ Smith
Journal of neuroscience research 68 (2), 127-137, 2002
522002
QSP toolbox: computational implementation of integrated workflow components for deploying multi-scale mechanistic models
Y Cheng, CJ Thalhauser, S Smithline, J Pagidala, M Miladinov, ...
The AAPS journal 19, 1002-1016, 2017
472017
Model‐based exposure–response analysis of apixaban to quantify bleeding risk in special populations of subjects undergoing orthopedic surgery
TA Leil, C Frost, X Wang, M Pfister, F LaCreta
CPT: Pharmacometrics & Systems Pharmacology 3 (9), 1-9, 2014
442014
Investigating transporter‐mediated drug‐drug interactions using a physiologically based pharmacokinetic model of rosuvastatin
Q Wang, M Zheng, T Leil
CPT: Pharmacometrics & Systems Pharmacology 6 (4), 228-238, 2017
372017
Evaluation of 4β‐Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model
TA Leil, S Kasichayanula, DW Boulton, F LaCreta
CPT: pharmacometrics & systems pharmacology 3 (6), 1-10, 2014
342014
Neurotrophin-4 is required for tolerance to morphine in the mouse
DJ Smith, TA Leil, X Liu
Neuroscience letters 340 (2), 103-106, 2003
302003
Tamoxifen Induces Expression of Immune Response–Related Genes in Cultured Normal Human Mammary Epithelial Cells
LJ Schild-Hay, TA Leil, RL Divi, OA Olivero, A Weston, MC Poirier
Cancer research 69 (3), 1150-1155, 2009
292009
Children’s Oncology Group Pilot Study. Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children’s Oncology …
EA Raetz, MS Cairo, MJ Borowitz, SM Blaney, MD Krailo, TA Leil, JM Reid, ...
J Clin Oncol 26 (22), 3756-3762, 2008
272008
Comparison of the pharmacokinetics and pharmacodynamics of dapagliflozin in patients with type 1 versus type 2 diabetes mellitus
W Tang, TA Leil, E Johnsson, DW Boulton, F LaCreta
Diabetes, Obesity and Metabolism 18 (3), 236-240, 2016
242016
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