Synthetic transcription elongation factors license transcription across repressive chromatin GS Erwin, MP Grieshop, A Ali, J Qi, M Lawlor, D Kumar, I Ahmad, ... Science 358 (6370), 1617-1622, 2017 | 112 | 2017 |
Mapping polyamide–DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites GS Erwin, D Bhimsaria, A Eguchi, AZ Ansari Angewandte Chemie 126 (38), 10288-10292, 2014 | 41 | 2014 |
Reprogramming cell fate with a genome-scale library of artificial transcription factors A Eguchi, MJ Wleklinski, MC Spurgat, EA Heiderscheit, AS Kropornicka, ... Proceedings of the National Academy of Sciences 113 (51), E8257-E8266, 2016 | 34 | 2016 |
Differential sensitivity of oligodendrocytes and motor neurons to reactive nitrogen species: implications for multiple sclerosis A Bishop, KG Hobbs, A Eguchi, S Jeffrey, L Smallwood, C Pennie, ... Journal of neurochemistry 109 (1), 93-104, 2009 | 33 | 2009 |
Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes ACY Chang, G Pardon, ACH Chang, H Wu, SG Ong, A Eguchi, S Ancel, ... Stem cell reports 16 (9), 2169-2181, 2021 | 27 | 2021 |
Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers A Eguchi, GO Lee, F Wan, GS Erwin, AZ Ansari Biochemical Journal 462 (3), 397-413, 2014 | 23 | 2014 |
Reprogramming cell fate with artificial transcription factors EA Heiderscheit, A Eguchi, MC Spurgat, AZ Ansari FEBS letters 592 (6), 888-900, 2018 | 21 | 2018 |
Mitigation of peroxynitrite‐mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS A Bishop, R Gooch, A Eguchi, S Jeffrey, L Smallwood, J Anderson, ... Journal of neurochemistry 109 (1), 74-84, 2009 | 16 | 2009 |
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs A Eguchi, AFGS Gonzalez, SI Torres-Bigio, K Koleckar, F Birnbaum, ... Proceedings of the National Academy of Sciences 120 (6), e2209967120, 2023 | 8 | 2023 |
Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome PB Finn, D Bhimsaria, A Ali, A Eguchi, AZ Ansari, PB Dervan PloS one 15 (12), e0243905, 2020 | 8 | 2020 |
Genome-wide mapping of drug-DNA interactions in cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin) GS Erwin, MP Grieshop, D Bhimsaria, A Eguchi, JA Rodríguez-Martínez, ... JoVE (Journal of Visualized Experiments), e53510, 2016 | 7 | 2016 |
Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates F Birnbaum, A Eguchi, G Pardon, ACY Chang, HM Blau NPJ Regenerative Medicine 7 (1), 19, 2022 | 6 | 2022 |
Artificial transcription factors and uses thereof A Eguchi, AZ Ansari US Patent 11,371,023, 2022 | 2 | 2022 |
Control of Cell Fate with Artificial Transcription Factors A Eguchi University of Wisconsin--Madison, 2016 | 2 | 2016 |
Abstract P2120: Microdystrophin Design Comparisons In Dystrophin-Deficient Cardiomyocytes A Eguchi, AF Gonzalez, S Torres-Bigio, S Bhimaraju, F Birnbaum, ... Circulation Research 131 (Suppl_1), AP2120-AP2120, 2022 | | 2022 |
Abstract P2117: TRF2 Rescues Pathogenic Phenotypes In Duchenne Muscular Dystrophy Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells A Eguchi, SI Torres-Bigio, AFG Gonzalez, K Koleckar, F Birnbaum, ... Circulation Research 131 (Suppl_1), AP2117-AP2117, 2022 | | 2022 |
Artificial Transcription Factors and Uses Thereof A Eguchi, AZ Ansari US Patent App. 17/349,243, 2022 | | 2022 |
TRF2 rescues pathogenic phenotypes in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs A Eguchi, SI Torres-Bigio, K Koleckar, F Birnbaum, HM Blau bioRxiv, 2022 | | 2022 |
Impaired Inside-out Force Transmission in Hipsc-cardiomyocyte Model of Duchenne Muscular Dystrophy Cardiomyopathy G Pardon, F Birnbaum, A Eguchi, HM Blau Circulation Research 127 (Suppl_1), A522-A522, 2020 | | 2020 |
Role of Telomere Dysfunction in Duchenne Muscular Dystrophy Cardiomyopathy A Eguchi, AC Chang, G Pardon, BL Pruitt, D Bernstein, HM Blau Circulation Research 125 (Suppl_1), A477-A477, 2019 | | 2019 |