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Syam Somasekharan
Syam Somasekharan
Assistant Professor, University of British Columbia
Verified email at mail.ubc.ca - Homepage
Title
Cited by
Cited by
Year
Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization
S Montessuit, SP Somasekharan, O Terrones, S Lucken-Ardjomande, ...
Cell 142 (6), 889-901, 2010
4672010
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
4332013
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
3112015
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
SP Somasekharan, A El-Naggar, G Leprivier, H Cheng, S Hajee, ...
Journal of Cell Biology 208 (7), 913-929, 2015
2882015
Co-translational assembly of proteasome subunits in NOT1-containing assemblysomes
OO Panasenko, SP Somasekharan, Z Villanyi, M Zagatti, F Bezrukov, ...
Nature structural & molecular biology 26 (2), 110-120, 2019
1112019
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ...
Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014
1042014
Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis
AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ...
EMBO reports 20 (12), e48375, 2019
842019
Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer
A Kretschmer, F Zhang, SP Somasekharan, C Tse, L Leachman, A Gleave, ...
Scientific reports 9 (1), 7826, 2019
562019
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response
A Jan, B Jansonius, A Delaidelli, SP Somasekharan, F Bhanshali, ...
Acta Neuropathologica 133, 101-119, 2017
522017
Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click–SILAC approach
SP Somasekharan, N Stoynov, B Rotblat, G Leprivier, JD Galpin, ...
Journal of proteomics 77, e1-e10, 2012
522012
G3BP1-linked mRNA partitioning supports selective protein synthesis in response to oxidative stress
SP Somasekharan, F Zhang, N Saxena, JN Huang, IC Kuo, C Low, R Bell, ...
Nucleic acids research 48 (12), 6855-6873, 2020
422020
TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis
SP Somasekharan, M Koc, A Morizot, O Micheau, PHB Sorensen, ...
Apoptosis 18, 324-336, 2013
352013
An Aqueous Extract of Marine Microalgae Exhibits Antimetastatic Activity through Preferential Killing of Suspended Cancer Cells and Anticolony Forming Activity
SP Somasekharan, A El-Naggar, PH Sorensen, Y Wang, H Cheng
Evidence-Based Complementary and Alternative Medicine 2016, 2016
292016
Regulation of AR mRNA translation in response to acute AR pathway inhibition
SP Somasekharan, N Saxena, F Zhang, E Beraldi, JN Huang, C Gentle, ...
Nucleic acids research 50 (2), 1069-1091, 2022
212022
Expression and localization of calcium-dependent protein kinase isoforms in chickpea
SRS Prakash, C Jayabaskaran
Journal of plant physiology 163 (11), 1135-1149, 2006
19*2006
SARS‐CoV‐2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets
SP Somasekharan, M Gleave
Febs Letters 595 (23), 2872-2896, 2021
162021
Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling
N Saxena, E Beraldi, L Fazli, SP Somasekharan, H Adomat, F Zhang, ...
EMBO Molecular Medicine 13 (5), e13427, 2021
132021
SILAC-based quantitative MS approach reveals Withaferin A regulated proteins in prostate cancer
R Kumar, D Nayak, SP Somasekharan
Journal of Proteomics 247, 104334, 2021
122021
Heterologous expression and biochemical characterization of two calcium-dependent protein kinase isoforms CaCPK1 and CaCPK2 from chickpea
SRS Prakash, C Jayabaskaran
Journal of plant physiology 163 (11), 1083-1093, 2006
92006
Cloning of two chickpea cDNAs encoding calcium-dependent protein kinase isoforms
SRS Prakash, C Jayabaskaran
Current Science, 72-77, 2007
22007
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