| Pressure-based long-range correction for Lennard-Jones interactions in molecular dynamics simulations: application to alkanes and interfaces P Lagüe, RW Pastor, BR Brooks The Journal of Physical Chemistry B 108 (1), 363-368, 2004 | 120 | 2004 |
| Lipid-mediated interactions between intrinsic membrane proteins: dependence on protein size and lipid composition P Lagüe, MJ Zuckermann, B Roux Biophysical journal 81 (1), 276-284, 2001 | 106 | 2001 |
| Molecular dynamics simulations of the influenza hemagglutinin fusion peptide in micelles and bilayers: conformational analysis of peptide and lipids P Lagüe, B Roux, RW Pastor Journal of molecular biology 354 (5), 1129-1141, 2005 | 99 | 2005 |
| Efficient restoration of the dystrophin gene reading frame and protein structure in DMD myoblasts using the CinDel method JP Iyombe-Engembe, DL Ouellet, X Barbeau, J Rousseau, ... Molecular Therapy-Nucleic Acids 5, 2016 | 98 | 2016 |
| CRISPR-induced deletion with saCas9 restores dystrophin expression in dystrophic models in vitro and in vivo BL Duchêne, K Cherif, JP Iyombe-Engembe, A Guyon, J Rousseau, ... Molecular Therapy 26 (11), 2604-2616, 2018 | 78 | 2018 |
| Lipid-mediated interactions between intrinsic membrane proteins: a theoretical study based on integral equations P Lagüe, MJ Zuckermann, B Roux Biophysical journal 79 (6), 2867-2879, 2000 | 60 | 2000 |
| Synergistic applications of MD and NMR for the study of biological systems O Fisette, P Lagüe, S Gagné, S Morin BioMed Research International 2012, 2012 | 59 | 2012 |
| TEM-1 backbone dynamics—insights from combined molecular dynamics and nuclear magnetic resonance O Fisette, S Morin, PY Savard, P Lagüe, SM Gagné Biophysical journal 98 (4), 637-645, 2010 | 50 | 2010 |
| Discovery of a Non-Estrogenic Irreversible Inhibitor of 17β-Hydroxysteroid Dehydrogenase Type 1 from 3-Substituted-16β-(m-carbamoylbenzyl)-estradiol Derivatives R Maltais, D Ayan, A Trottier, X Barbeau, P Lagüe, JE Bouchard, ... Journal of medicinal chemistry 57 (1), 204-222, 2014 | 45 | 2014 |
| Quinazoline‐4‐piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells EE Shayhidin, E Forcellini, MC Boulanger, A Mahmut, S Dautrey, ... British journal of pharmacology 172 (16), 4189-4199, 2015 | 42 | 2015 |
| Structural characterization of the tunnels of Mycobacterium tuberculosis truncated hemoglobin N from molecular dynamics simulations R Daigle, M Guertin, P Lagüe Proteins: Structure, Function, and Bioinformatics 75 (3), 735-747, 2009 | 38 | 2009 |
| Protein inclusion in lipid membranes: a theory based on the hypernetted chain integral equation P Lagüe, MJ Zuckermann, B Roux Faraday discussions 111, 165-172, 1999 | 38 | 1999 |
| Determining the mode of action involved in the antimicrobial activity of synthetic peptides: a solid-state NMR and FTIR study A Lorin, M Noël, MÈ Provencher, V Turcotte, S Cardinal, P Lagüe, ... Biophysical journal 103 (7), 1470-1479, 2012 | 37 | 2012 |
| Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water YH Ouellet, R Daigle, P Lagüe, D Dantsker, M Milani, M Bolognesi, ... Journal of Biological Chemistry 283 (40), 27270-27278, 2008 | 36 | 2008 |
| Is there nascent structure in the intrinsically disordered region of troponin I? O Julien, P Mercier, CN Allen, O Fisette, CHI Ramos, P Lagüe, ... Proteins: Structure, Function, and Bioinformatics 79 (4), 1240-1250, 2011 | 35 | 2011 |
| Antibiotic resistance due to an unusual ColE1-type replicon plasmid in Aeromonas salmonicida AT Vincent, JG Emond-Rheault, X Barbeau, SA Attéré, M Frenette, ... Microbiology 162 (6), 942-953, 2016 | 34 | 2016 |
| The influenza fusion peptide promotes lipid polar head intrusion through hydrogen bonding with phosphates and N‐terminal membrane insertion depth S Légaré, P Lagüe Proteins: Structure, Function, and Bioinformatics 82 (9), 2118-2127, 2014 | 33 | 2014 |
| Theoretical investigations of nitric oxide channeling in Mycobacterium tuberculosis truncated hemoglobin N R Daigle, JA Rousseau, M Guertin, P Lagüe Biophysical journal 97 (11), 2967-2977, 2009 | 33 | 2009 |
| Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1 E Forcellini, S Boutin, CA Lefebvre, EE Shayhidin, MC Boulanger, ... European journal of medicinal chemistry 147, 130-149, 2018 | 32 | 2018 |
| Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties C Ouellet, R Maltais, É Ouellet, X Barbeau, P Lagüe, D Poirier European Journal of Medicinal Chemistry 119, 169-182, 2016 | 30 | 2016 |
Xavier BarbeauNuChem SciencesAdresse e-mail validée de nuchemsciences.com
