Kush Dalal
Kush Dalal
Vancouver area
Verified email at interchange.ubc.ca
Title
Cited by
Cited by
Year
Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA
M Alami, K Dalal, B Lelj‐Garolla, SG Sligar, F Duong
The EMBO journal 26 (8), 1995-2004, 2007
1822007
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling
BD Fonseca, GH Diering, MA Bidinosti, K Dalal, T Alain, AD Balgi, ...
Journal of Biological Chemistry 287 (21), 17530-17545, 2012
1272012
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer
K Dalal, M Roshan-Moniri, A Sharma, H Li, F Ban, M Hessein, M Hsing, ...
Journal of Biological Chemistry 289 (38), 26417-26429, 2014
1042014
Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor
H Li, F Ban, K Dalal, E Leblanc, K Frewin, D Ma, H Adomat, PS Rennie, ...
Journal of medicinal chemistry 57 (15), 6458-6467, 2014
842014
Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
N Lallous, K Dalal, A Cherkasov, PS Rennie
International journal of molecular sciences 14 (6), 12496-12519, 2013
632013
Best practices of computer-aided drug discovery: lessons learned from the development of a preclinical candidate for prostate cancer with a new mechanism of action
F Ban, K Dalal, H Li, E LeBlanc, PS Rennie, A Cherkasov
Journal of chemical information and modeling 57 (5), 1018-1028, 2017
592017
Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase
K Dalal, CS Chan, SG Sligar, F Duong
Proceedings of the National Academy of Sciences 109 (11), 4104-4109, 2012
572012
RPA nucleic acid-binding properties of IFI16-HIN200
H Yan, K Dalal, BK Hon, P Youkharibache, D Lau, F Pio
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (7-8), 1087 …, 2008
552008
SecYEG activates GTPases to drive the completion of cotranslational protein targeting
D Akopian, K Dalal, K Shen, F Duong, S Shan
Journal of Cell Biology 200 (4), 397-405, 2013
502013
Moving towards precision urologic oncology: targeting enzalutamide-resistant prostate cancer and mutated forms of the androgen receptor using the novel inhibitor darolutamide …
H Borgmann, N Lallous, D Ozistanbullu, E Beraldi, N Paul, K Dalal, L Fazli, ...
European urology 73 (1), 4-8, 2018
442018
Structure, binding, and activity of Syd, a SecY-interacting protein
K Dalal, N Nguyen, M Alami, J Tan, TF Moraes, WC Lee, R Maurus, ...
Journal of Biological Chemistry 284 (12), 7897-7902, 2009
432009
Reconstitution of the SecY translocon in nanodiscs
K Dalal, F Duong
Protein Secretion, 145-156, 2010
382010
The maltose ABC transporter: action of membrane lipids on the transporter stability, coupling and ATPase activity
H Bao, K Dalal, V Wang, I Rouiller, F Duong
Biochimica Et Biophysica Acta (BBA)-Biomembranes 1828 (8), 1723-1730, 2013
342013
Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer
MS Butler, M Roshan-Moniri, M Hsing, D Lau, A Kim, P Yen, M Mroczek, ...
Oncotarget 8 (26), 42438, 2017
282017
The SecY complex: conducting the orchestra of protein translocation
K Dalal, F Duong
Trends in cell biology 21 (9), 506-514, 2011
262011
The SecY complex forms a channel capable of ionic discrimination
K Dalal, F Duong
EMBO reports 10 (7), 762-768, 2009
252009
Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer
K Dalal, F Ban, H Li, H Morin, M Roshan-Moniri, KJ Tam, A Shepherd, ...
Cancer letters 437, 35-43, 2018
242018
Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor–Chromatin Interactions
K Dalal, M Che, NS Que, A Sharma, R Yang, N Lallous, H Borgmann, ...
Molecular cancer therapeutics 16 (10), 2281-2291, 2017
192017
Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI-16
K Dalal, F Pio
FEBS letters 580 (13), 3083-3090, 2006
162006
Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner
KJ Tam, K Dalal, M Hsing, CW Cheng, S Khosravi, P Yenki, C Tse, ...
Oncotarget 8 (6), 9617, 2017
152017
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