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Tõnis Lehto
Tõnis Lehto
Post doctoral fellow, University of Tartu
Verified email at ut.ee
Title
Cited by
Cited by
Year
PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo
KL Veiman, K Künnapuu, T Lehto, K Kiisholts, K Pärn, Ü Langel, ...
Journal of Controlled Release 209, 238-247, 2015
1322015
PepFect14 peptide vector for efficient gene delivery in cell cultures
KL Veiman, I Mäger, K Ezzat, H Margus, T Lehto, K Langel, K Kurrikoff, ...
Molecular pharmaceutics 10 (1), 199-210, 2013
1012013
Saturated fatty acid analogues of cell-penetrating peptide PepFect14: role of fatty acid modification in complexation and delivery of splice-correcting oligonucleotides
T Lehto, L Vasconcelos, H Margus, R Figueroa, M Pooga, M Hällbrink, ...
Bioconjugate chemistry 28 (3), 782-792, 2017
492017
Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide
K Kurrikoff, KL Veiman, K Künnapuu, EM Peets, T Lehto, L Pärnaste, ...
Scientific reports 7 (1), 17056, 2017
402017
Efficient peptide-mediated in vitro delivery of Cas9 RNP
O Gustafsson, J Rädler, S Roudi, T Lehto, M Hällbrink, T Lehto, D Gupta, ...
Pharmaceutics 13 (6), 878, 2021
272021
Peptide-based vectors: recent developments
CP Cerrato, T Lehto, Ü Langel
Biomolecular concepts 5 (6), 479-488, 2014
252014
Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides
CP Cerrato, T Kivijärvi, R Tozzi, T Lehto, M Gestin, Ü Langel
Journal of Materials Chemistry B 8 (47), 10825-10836, 2020
192020
Refinement of a quantitative structure–activity relationship model for prediction of cell-penetrating peptide based transfection systems
M Dowaidar, J Regberg, DA Dobchev, T Lehto, M Hällbrink, M Karelson, ...
International Journal of Peptide Research and Therapeutics 23, 91-100, 2017
192017
Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy
L Vasconcelos, T Lehto, F Madani, V Radoi, M Hällbrink, V Vukojević, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 491-504, 2018
162018
Astrocytes promote ethanol-induced enhancement of intracellular Ca2+ signals through intercellular communication with neurons
HB Kim, J Morris, K Miyashiro, T Lehto, Ü Langel, J Eberwine, JY Sul
Iscience 24 (5), 2021
92021
Novel orthogonally hydrocarbon-modified cell-penetrating peptide nanoparticles mediate efficient delivery of splice-switching antisense oligonucleotides in vitro and in vivo
S Bazaz, T Lehto, R Tops, O Gissberg, D Gupta, B Bestas, J Bost, ...
Biomedicines 9 (8), 1046, 2021
62021
Characterization of nucleic acid delivery with fatty acid modified cell-penetrating peptide nanoparticle formulations
T Lehto
Department of Biochemistry and Biophysics, Stockholm University, 2018
12018
Guidelines for developing safe and efficient acylated cell-penetrating peptides for nanoparticle mediated non-covalent nucleic acid delivery in vivo
T Lehto
2018
Principles of in vivo nucleic acid delivery with acylated cell-penetrating peptides
T Lehto, KL Veiman, M Hällbrink, Ü Langel
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Articles 1–14