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Xiaoguang Liu
Xiaoguang Liu
Zhejiang University
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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ...
Nature 593 (7860), 586-590, 2021
8622021
The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
G Lei, Y Zhang, P Koppula, X Liu, J Zhang, SH Lin, JA Ajani, Q Xiao, ...
Cell research 30 (2), 146-162, 2020
7262020
BAP1 links metabolic regulation of ferroptosis to tumour suppression
Y Zhang, J Shi, X Liu, L Feng, Z Gong, P Koppula, K Sirohi, X Li, Y Wei, ...
Nature cell biology 20 (10), 1181-1192, 2018
6532018
mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation
Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ...
Nature communications 12 (1), 1-14, 2021
3692021
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis
X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ...
Nature cell biology 25 (3), 404-414, 2023
3052023
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
X Liu, K Olszewski, Y Zhang, EW Lim, J Shi, X Zhang, J Zhang, H Lee, ...
Nature cell biology 22 (4), 476-486, 2020
2712020
Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription
W Wei, X Liu, J Chen, S Gao, L Lu, H Zhang, G Ding, Z Wang, Z Chen, ...
Cell research 27 (7), 898-915, 2017
2162017
A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers
P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ...
Nature communications 13 (1), 2206, 2022
1682022
Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT)
Q Zhang, X Liu, W Gao, P Li, J Hou, J Li, J Wong
Journal of Biological Chemistry 289 (9), 5986-5996, 2014
1682014
A targetable LIFR− NF-κB− LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
F Yao, Y Deng, Y Zhao, Y Mei, Y Zhang, X Liu, C Martinez, X Su, ...
Nature communications 12 (1), 7333, 2021
1312021
Large-scale identification of protein crotonylation reveals its role in multiple cellular functions
W Wei, A Mao, B Tang, Q Zeng, S Gao, X Liu, L Lu, W Li, JX Du, J Li, ...
Journal of proteome research 16 (4), 1743-1752, 2017
1202017
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity
G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ...
Oncogene 40 (20), 3533-3547, 2021
1152021
MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300
X Liu, W Wei, Y Liu, X Yang, J Wu, Y Zhang, Q Zhang, T Shi, JX Du, ...
Cell Discovery 3 (1), 1-17, 2017
1072017
NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation
X Liu, Y Zhang, L Zhuang, K Olszewski, B Gan
Genes & diseases 8 (6), 731-745, 2021
652021
STIM2 interacts with AMPK and regulates calcium-induced AMPK activation
AS Chauhan, X Liu, J Jing, H Lee, RK Yadav, J Liu, Y Zhou, B Gan
The FASEB Journal 33 (2), 2957, 2019
432019
SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells
Y Yan, H Teng, Q Hang, L Kondiparthi, G Lei, A Horbath, X Liu, C Mao, ...
Nature communications 14 (1), 3673, 2023
352023
H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death
Y Zhang, J Shi, X Liu, Z Xiao, G Lei, H Lee, P Koppula, W Cheng, C Mao, ...
Cancer research 80 (11), 2243-2256, 2020
282020
Disulfidptosis: disulfide stress–induced cell death
X Liu, L Zhuang, B Gan
Trends in Cell Biology, 2023
252023
KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
P Koppula, K Olszewski, Y Zhang, L Kondiparthi, X Liu, G Lei, M Das, ...
Iscience 24 (6), 2021
252021
Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ...
Nature 596 (7873), E13-E13, 2021
152021
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