Lyle McKinnon
Lyle McKinnon
University of Manitoba
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Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women
NR Klatt, R Cheu, K Birse, AS Zevin, M Perner, L NoŽl-Romas, A Grobler, ...
Science 356 (6341), 938-945, 2017
The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1
C Cicala, E Martinelli, JP McNally, DJ Goode, R Gopaul, J Hiatt, K Jelicic, ...
Proceedings of the National Academy of Sciences 106 (49), 20877-20882, 2009
Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy
SN Byrareddy, J Arthos, C Cicala, F Villinger, KT Ortiz, D Little, N Sidell, ...
Science 354 (6309), 197-202, 2016
Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV†…
KB Arnold, A Burgener, K Birse, L Romas, LJ Dunphy, K Shahabi, M Abou, ...
Mucosal immunology 9 (1), 194-205, 2016
Microbial translocation and microbiome dsybiosis in HIV-associated immune activation
AS Zevin, L McKinnon, A Burgener, NR Klatt
Current Opinion in HIV and AIDS 11 (2), 182, 2016
Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility
LR McKinnon, B Nyanga, D Chege, P Izulla, M Kimani, S Huibner, ...
The Journal of Immunology 187 (11), 6032-6042, 2011
Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study
L Masson, K Mlisana, F Little, L Werner, NN Mkhize, K Ronacher, ...
Sexually transmitted infections 90 (8), 580-587, 2014
Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection
RT Lester, XD Yao, TB Ball, LR McKinnon, R Kaul, C Wachihi, W Jaoko, ...
Aids 22 (6), 685-694, 2008
The evolving facets of bacterial vaginosis: implications for HIV transmission
LR McKinnon, SL Achilles, CS Bradshaw, A Burgener, T Crucitti, ...
AIDS research and human retroviruses 35 (3), 219-228, 2019
Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation
CJ Kim, LR McKinnon, C Kovacs, G Kandel, S Huibner, D Chege, ...
The Journal of Immunology 191 (5), 2164-2173, 2013
Quality and quantity: mucosal CD4+ T cells and HIV susceptibility
LR McKinnon, R Kaul
Current Opinion in HIV and AIDS 7 (2), 195-202, 2012
Microbiome composition and function drives wound-healing impairment in the female genital tract
AS Zevin, IY Xie, K Birse, K Arnold, L Romas, G Westmacott, RM Novak, ...
PLoS pathogens 12 (9), e1005889, 2016
Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women
LR McKinnon, LJ Liebenberg, N Yende-Zuma, D Archary, S Ngcapu, ...
Nature medicine 24 (4), 491-496, 2018
Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes
A Sivro, A Schuetz, D Sheward, V Joag, S Yegorov, LJ Liebenberg, ...
Science translational medicine 10 (425), eaam6354, 2018
Identification of preferential CD4+ T-cell targets for HIV infection in the cervix
VR Joag, LR McKinnon, J Liu, ST Kidane, MH Yudin, B Nyanga, ...
Mucosal immunology 9 (1), 1-12, 2016
Genital immunology and HIV susceptibility in young women
TJ Yi, B Shannon, J Prodger, L McKinnon, R Kaul
American journal of reproductive immunology 69, 74-79, 2013
HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers
RT Lester, XD Yao, TB Ball, LR McKinnon, WR Omange, R Kaul, ...
PloS one 4 (5), e5644, 2009
Biological factors that may contribute to regional and racial disparities in HIV prevalence
R Kaul, CR Cohen, D Chege, TJ Yi, W Tharao, LR McKinnon, R Remis, ...
American journal of reproductive immunology 65 (3), 317-324, 2011
High HIV risk in a cohort of male sex workers from Nairobi, Kenya
LR McKinnon, G Gakii, JA Juno, P Izulla, J Munyao, N Ireri, CW Kariuki, ...
Sexually transmitted infections 90 (3), 237-242, 2014
Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya
D Chege, Y Chai, S Huibner, T Kain, C Wachihi, M Kimani, S Barasa, ...
Public Library of Science 7 (8), e43670, 2012
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