Stefan Schildknecht
Stefan Schildknecht
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Rapid, complete and large‐scale generation of post‐mitotic neurons from the human LUHMES cell line
D Scholz, D Pöltl, A Genewsky, M Weng, T Waldmann, S Schildknecht, ...
Journal of neurochemistry 119 (5), 957-971, 2011
Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity Implications for mitochondrial oxidative stress and nitrate tolerance
P Wenzel, U Hink, M Oelze, S Schuppan, K Schaeuble, S Schildknecht, ...
Journal of Biological Chemistry 282 (1), 792-799, 2007
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of toxicology 91 (11), 3477-3505, 2017
Vascular aging: chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease
MM Bachschmid, S Schildknecht, R Matsui, R Zee, D Haeussler, ...
Annals of medicine 45 (1), 17-36, 2013
Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure
A Daiber, M Oelze, M Coldewey, K Kaiser, C Huth, S Schildknecht, ...
Biochemical and biophysical research communications 338 (4), 1865-1874, 2005
Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies
S Schildknecht, HR Gerding, C Karreman, M Drescher, HA Lashuel, ...
Journal of neurochemistry 125 (4), 491-511, 2013
Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite
S Schildknecht, R Pape, N Müller, M Robotta, A Marquardt, A Bürkle, ...
Journal of Biological Chemistry 286 (7), 4991-5002, 2011
Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system
M Bachschmid, S Schildknecht, V Ullrich
Biochemical and biophysical research communications 338 (1), 536-542, 2005
Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
S Schildknecht, D Pöltl, DM Nagel, F Matt, D Scholz, J Lotharius, ...
Toxicology and applied pharmacology 241 (1), 23-35, 2009
Redox regulation: a new challenge for pharmacology
D Frein, S Schildknecht, M Bachschmid, V Ullrich
Biochemical pharmacology 70 (6), 811-823, 2005
Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes
H Lohren, L Blagojevic, R Fitkau, F Ebert, S Schildknecht, M Leist, ...
Journal of trace elements in medicine and biology 32, 200-208, 2015
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
AK Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, ...
Cell death & disease 5 (5), e1222-e1222, 2014
A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles
L Hoelting, B Scheinhardt, O Bondarenko, S Schildknecht, M Kapitza, ...
Archives of toxicology 87 (4), 721-733, 2013
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure
B Zimmer, S Schildknecht, PB Kuegler, V Tanavde, S Kadereit, M Leist
Toxicological Sciences 121 (2), 357-367, 2011
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ...
Archives of toxicology 89 (9), 1599-1618, 2015
Alpha‐Synuclein Binds to the Inner Membrane of Mitochondria in an α‐Helical Conformation
M Robotta, HR Gerding, A Vogel, K Hauser, S Schildknecht, C Karreman, ...
Chembiochem 15 (17), 2499-2502, 2014
Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases
S Schildknecht, C Karreman, D Pöltl, L Efrémova, C Kullmann, S Gutbier, ...
Alternatives to animal experimentation: ALTEX 30 (4), 427-444, 2013
COX‐2 inhibitors selectively block prostacyclin synthesis in endotoxin exposed vascular smooth muscle cells
S Schildknecht, M Bachschmid, A Baumann, V Ullrich
The FASEB journal 18 (6), 757-759, 2004
Peroxynitrite as regulator of vascular prostanoid synthesis
S Schildknecht, V Ullrich
Archives of biochemistry and biophysics 484 (2), 183-189, 2009
Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants
C Hirsch, B Striegl, S Mathes, C Adlhart, M Edelmann, E Bono, S Gaan, ...
Archives of toxicology 91 (1), 407-425, 2017
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