Andrew Roth
Andrew Roth
Assistant Professor, University of British Columbia
Verified email at bccrc.ca - Homepage
Title
Cited by
Cited by
Year
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ...
Nature 486 (7403), 395-399, 2012
16572012
PyClone: statistical inference of clonal population structure in cancer
A Roth, J Khattra, D Yap, A Wan, E Laks, J Biele, G Ha, S Aparicio, ...
Nature methods 11 (4), 396-398, 2014
5222014
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ...
Nature 518 (7539), 422-426, 2015
4712015
Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers
A Heravi-Moussavi, MS Anglesio, SWG Cheng, J Senz, W Yang, ...
New England Journal of Medicine 366 (3), 234-242, 2012
3512012
Distinct evolutionary trajectories of primary high‐grade serous ovarian cancers revealed through spatial mutational profiling
A Bashashati, G Ha, A Tone, J Ding, LM Prentice, A Roth, J Rosner, ...
The Journal of pathology 231 (1), 21-34, 2013
3322013
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
RD Morin, K Mungall, E Pleasance, AJ Mungall, R Goya, RD Huff, ...
Blood 122 (7), 1256-1265, 2013
3302013
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
G Ha, A Roth, J Khattra, J Ho, D Yap, LM Prentice, N Melnyk, ...
Genome research 24 (11), 1881-1893, 2014
2222014
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer
G Ha, A Roth, D Lai, A Bashashati, J Ding, R Goya, R Giuliany, J Rosner, ...
Genome research 22 (10), 1995-2007, 2012
2112012
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351-357, 2016
2102016
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
A McPherson, A Roth, E Laks, T Masud, A Bashashati, AW Zhang, G Ha, ...
Nature genetics 48 (7), 758, 2016
1902016
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data
A Roth, J Ding, R Morin, A Crisan, G Ha, R Giuliany, A Bashashati, M Hirst, ...
Bioinformatics 28 (7), 907-913, 2012
1902012
Feature-based classifiers for somatic mutation detection in tumour–normal paired sequencing data
J Ding, A Bashashati, A Roth, A Oloumi, K Tse, T Zeng, G Haffari, M Hirst, ...
Bioinformatics 28 (2), 167-175, 2012
1352012
Mutational context and diverse clonal development in early and late bladder cancer
I Nordentoft, P Lamy, K Birkenkamp-Demtröder, K Shumansky, S Vang, ...
Cell reports 7 (5), 1649-1663, 2014
1062014
Histological transformation and progression in follicular lymphoma: a clonal evolution study
R Kridel, FC Chan, A Mottok, M Boyle, P Farinha, K Tan, B Meissner, ...
PLoS medicine 13 (12), e1002197, 2016
1012016
Interfaces of malignant and immunologic clonal dynamics in ovarian cancer
AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ...
Cell 173 (7), 1755-1769. e22, 2018
952018
Clonal genotype and population structure inference from single-cell tumor sequencing
A Roth, A McPherson, E Laks, J Biele, D Yap, A Wan, MA Smith, ...
Nature methods 13 (7), 573-576, 2016
672016
ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data
S Salehi, A Steif, A Roth, S Aparicio, A Bouchard-Côté, SP Shah
Genome biology 18 (1), 44, 2017
342017
Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression
AP Hegle, H Nazzari, A Roth, D Angoli, EA Accili
American Journal of Physiology-Cell Physiology 298 (5), C1066-C1076, 2010
272010
E-scape: interactive visualization of single-cell phylogenetics and cancer evolution
MA Smith, CB Nielsen, FC Chan, A McPherson, A Roth, H Farahani, ...
Nature methods 14 (6), 549-550, 2017
172017
ReMixT: clone-specific genomic structure estimation in cancer
AW McPherson, A Roth, G Ha, C Chauve, A Steif, CPE de Souza, P Eirew, ...
Genome biology 18 (1), 1-14, 2017
132017
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