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Paul Baxter
Paul Baxter
Verified email at ed.ac.uk
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Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ...
Nature communications 8 (1), 15132, 2017
2682017
Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes
PS Baxter, GE Hardingham
Free Radical Biology and Medicine 100, 147-152, 2016
2222016
Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand
FX Soriano, MA Martel, S Papadia, A Vaslin, P Baxter, C Rickman, ...
Journal of Neuroscience 28 (42), 10696-10710, 2008
1842008
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2
KFS Bell, B Al-Mubarak, MA Martel, S McKay, N Wheelan, P Hasel, ...
Nature communications 6 (1), 7066, 2015
1782015
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning
KF Bell, B Al-Mubarak, JH Fowler, PS Baxter, K Gupta, T Tsujita, ...
Proceedings of the National Academy of Sciences 108 (1), E1-E2, 2011
1572011
Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin
FX Soriano, P Baxter, LM Murray, MB Sporn, TH Gillingwater, ...
Molecules and cells 27, 279-282, 2009
1442009
Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H‐1, 2‐dithiole‐3‐thione
FX Soriano, F Léveillé, S Papadia, LG Higgins, J Varley, P Baxter, ...
Journal of neurochemistry 107 (2), 533-543, 2008
1422008
Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system
PS Baxter, KFS Bell, P Hasel, AM Kaindl, M Fricker, D Thomson, ...
Nature communications 6 (1), 6761, 2015
1392015
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance
C Nazzaro, B Greco, M Cerovic, P Baxter, T Rubino, M Trusel, D Parolaro, ...
Nature neuroscience 15 (2), 284-293, 2012
1062012
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology
Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley, D Hampton, M Torvell, ...
Nature communications 13 (1), 135, 2022
1052022
Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms
K Gupta, R Patani, P Baxter, A Serio, D Story, T Tsujita, JD Hayes, ...
Cell Death & Differentiation 19 (5), 779-787, 2012
1012012
Phosphoinositide 3-Kinases Upregulate System xc via Eukaryotic Initiation Factor 2α and Activating Transcription Factor 4 – A Pathway Active in …
J Lewerenz, P Baxter, R Kassubek, P Albrecht, J Van Liefferinge, ...
Antioxidants & redox signaling 20 (18), 2907-2922, 2014
712014
Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes
PS Baxter, O Dando, K Emelianova, X He, S McKay, GE Hardingham, ...
Cell reports 34 (12), 2021
692021
Mitochondrial dysfunction induced by nuclear poly (ADP-ribose) polymerase-1: a treatable cause of cell death in stroke
P Baxter, Y Chen, Y Xu, RA Swanson
Translational stroke research 5, 136-144, 2014
682014
Pituitary adenylate cyclase‐activating peptide induces long‐lasting neuroprotection through the induction of activity‐dependent signaling via the cyclic AMP response element …
PS Baxter, MA Martel, A McMahon, PC Kind, GE Hardingham
Journal of neurochemistry 118 (3), 365-378, 2011
542011
Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1
J McQueen, TJ Ryan, S McKay, K Marwick, P Baxter, SM Carpanini, ...
Elife 6, e17161, 2017
532017
Input-output relationship of CA1 pyramidal neurons reveals intact homeostatic mechanisms in a mouse model of fragile X syndrome
SA Booker, LS De Oliveira, NJ Anstey, Z Kozic, OR Dando, AD Jackson, ...
Cell Reports 32 (6), 2020
422020
The developmental shift of NMDA receptor composition proceeds independently of GluN2 subunit-specific GluN2 C-terminal sequences
S McKay, TJ Ryan, J McQueen, T Indersmitten, KFM Marwick, P Hasel, ...
Cell reports 25 (4), 841-851. e4, 2018
422018
Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression
MA Martel, FX Soriano, P Baxter, C Rickman, R Duncan, DJA Wyllie, ...
Channels 3 (1), 12-15, 2009
422009
Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription
J Qiu, O Dando, PS Baxter, P Hasel, S Heron, TI Simpson, ...
Nature Protocols 13 (10), 2176-2199, 2018
332018
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