| Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 508 | 2021 |
| Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells EP Mimitou, A Cheng, A Montalbano, S Hao, M Stoeckius, M Legut, ... Nature methods 16 (5), 409-412, 2019 | 409 | 2019 |
| Massively parallel Cas13 screens reveal principles for guide RNA design HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ... Nature biotechnology 38 (6), 722-727, 2020 | 266 | 2020 |
| Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 MD Crowther, G Dolton, M Legut, ME Caillaud, A Lloyd, M Attaf, ... Nature immunology 21 (2), 178-185, 2020 | 230 | 2020 |
| Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies PM Maciocia, PA Wawrzyniecka, B Philip, I Ricciardelli, AU Akarca, ... Nature medicine 23 (12), 1416-1423, 2017 | 229 | 2017 |
| CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells M Legut, G Dolton, AA Mian, OG Ottmann, AK Sewell Blood, The Journal of the American Society of Hematology 131 (3), 311-322, 2018 | 214 | 2018 |
| The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy M Legut, DK Cole, AK Sewell Cellular & molecular immunology 12 (6), 656-668, 2015 | 136 | 2015 |
| A genome-scale screen for synthetic drivers of T cell proliferation M Legut, Z Gajic, M Guarino, Z Daniloski, JA Rahman, X Xue, C Lu, L Lu, ... Nature 603 (7902), 728-735, 2022 | 102 | 2022 |
| The T cell antigen receptor: the Swiss army knife of the immune system M Attaf, M Legut, DK Cole, AK Sewell Clinical & Experimental Immunology 181 (1), 1-18, 2015 | 93 | 2015 |
| Peptide–MHC class I tetramers can fail to detect relevant functional T cell clonotypes and underestimate antigen-reactive T cell populations C Rius, M Attaf, K Tungatt, V Bianchi, M Legut, A Bovay, M Donia, ... The Journal of Immunology 200 (7), 2263-2279, 2018 | 91 | 2018 |
| Optimized peptide–MHC multimer protocols for detection and isolation of autoimmune T-cells G Dolton, E Zervoudi, C Rius, A Wall, HL Thomas, A Fuller, L Yeo, ... Frontiers in immunology 9, 1378, 2018 | 77 | 2018 |
| PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer M Donia, JW Kjeldsen, R Andersen, MCW Westergaard, V Bianchi, ... Clinical Cancer Research 23 (19), 5779-5788, 2017 | 57 | 2017 |
| High-throughput screens of PAM-flexible Cas9 variants for gene knockout and transcriptional modulation M Legut, Z Daniloski, X Xue, D McKenzie, X Guo, HH Wessels, ... Cell reports 30 (9), 2859-2868. e5, 2020 | 52 | 2020 |
| Incorporation of peptides targeting EGFR and FGFR1 into the adenoviral fiber knob domain and their evaluation as targeted cancer therapies H Uusi-Kerttula, M Legut, J Davies, R Jones, E Hudson, L Hanna, ... Human gene therapy 26 (5), 320-329, 2015 | 46 | 2015 |
| Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines–in vitro studies M Legut, D Lipka, N Filipczak, A Piwoni, A Kozubek, J Gubernator International journal of nanomedicine, 653-668, 2014 | 46 | 2014 |
| Vitamin C-driven epirubicin loading into liposomes D Lipka, J Gubernator, N Filipczak, S Barnert, R Süss, M Legut, ... International journal of nanomedicine, 3573-3585, 2013 | 35 | 2013 |
| TCR‐induced alteration of primary MHC peptide anchor residue F Madura, PJ Rizkallah, M Legut, CJ Holland, A Fuller, A Bulek, ... European journal of immunology 49 (7), 1052-1066, 2019 | 30 | 2019 |
| Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope DK Cole, A Fuller, G Dolton, E Zervoudi, M Legut, K Miles, L Blanchfield, ... Frontiers in immunology 8, 1503, 2017 | 30 | 2017 |
| Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy G Dolton, C Rius, A Wall, B Szomolay, V Bianchi, SAE Galloway, ... Cell 186 (16), 3333-3349. e27, 2023 | 28 | 2023 |
| Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells A Méndez-Mancilla, HH Wessels, M Legut, A Kadina, M Mabuchi, ... Cell chemical biology 29 (2), 321-327. e4, 2022 | 28 | 2022 |
