Identification and functional characterization of brainstem cannabinoid CB2 receptors MD Van Sickle, M Duncan, PJ Kingsley, A Mouihate, P Urbani, K Mackie, ... Science 310 (5746), 329-332, 2005 | 1906 | 2005 |
Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome MD Coates, CR Mahoney, DR Linden, JE Sampson, J Chen, H Blaszyk, ... Gastroenterology 126 (7), 1657-1664, 2004 | 958 | 2004 |
Endocannabinoid signaling at the periphery: 50 years after THC M Maccarrone, I Bab, T Bíró, GA Cabral, SK Dey, V Di Marzo, JC Konje, ... Trends in pharmacological sciences 36 (5), 277-296, 2015 | 787 | 2015 |
Role for protease activity in visceral pain in irritable bowel syndrome N Cenac, CN Andrews, M Holzhausen, K Chapman, G Cottrell, ... The Journal of clinical investigation 117 (3), 636-647, 2007 | 716 | 2007 |
Recurrent aphthous ulcers today: a review of the growing knowledge SS Natah, YT Konttinen, NS Enattah, N Ashammakhi, KA Sharkey, ... International journal of oral and maxillofacial surgery 33 (3), 221-234, 2004 | 623 | 2004 |
Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. BK Reuter, S Asfaha, A Buret, KA Sharkey, JL Wallace The Journal of clinical investigation 98 (9), 2076-2085, 1996 | 565 | 1996 |
Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway N Vergnolle, NW Bunnett, KA Sharkey, V Brussee, SJ Compton, EF Grady, ... Nature medicine 7 (7), 821-826, 2001 | 561 | 2001 |
Cannabinoids and the gut: new developments and emerging concepts AA Izzo, KA Sharkey Pharmacology & therapeutics 126 (1), 21-38, 2010 | 515 | 2010 |
Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation K Riazi, MA Galic, JB Kuzmiski, W Ho, KA Sharkey, QJ Pittman Proceedings of the National Academy of Sciences 105 (44), 17151-17156, 2008 | 492 | 2008 |
Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis BD Gulbransen, M Bashashati, SA Hirota, X Gui, JA Roberts, ... Nature medicine 18 (4), 600-604, 2012 | 448 | 2012 |
Novel functional roles for enteric glia in the gastrointestinal tract BD Gulbransen, KA Sharkey Nature reviews Gastroenterology & hepatology 9 (11), 625-632, 2012 | 408 | 2012 |
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity JL Wallace, A Bak, W McKnight, S Asfaha, KA Sharkey, WK MacNaughton Gastroenterology 115 (1), 101-109, 1998 | 408 | 1998 |
Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte–endothelium interactions in endotoxemia MJ Hickey, KA Sharkey, EG Sihota, PH Reinhardt, JD Macmickeng, ... The FASEB Journal 11 (12), 955-964, 1997 | 357 | 1997 |
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation KL Wright, M Duncan, KA Sharkey British journal of pharmacology 153 (2), 263-270, 2008 | 343 | 2008 |
Inflammatory neuropathies of the enteric nervous system R De Giorgio, S Guerrini, G Barbara, V Stanghellini, F De Ponti, ... Gastroenterology 126 (7), 1872-1883, 2004 | 338 | 2004 |
Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis DR Linden, JX Chen, MD Gershon, KA Sharkey, GM Mawe American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (1 …, 2003 | 330 | 2003 |
Activation of colonic mucosal 5-HT4 receptors accelerates propulsive motility and inhibits visceral hypersensitivity JM Hoffman, K Tyler, SJ MacEachern, OB Balemba, AC Johnson, ... Gastroenterology 142 (4), 844-854. e4, 2012 | 317 | 2012 |
Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret MD Van Sickle, LD Oland, W Ho, CJ Hillard, KEN Mackie, JS Davison, ... Gastroenterology 121 (4), 767-774, 2001 | 306 | 2001 |
Sensory substance P innervation of the stomach and pancreas: demonstration of capsaicin-sensitive sensory neurons in the rat by combined immunohistochemistry and retrograde tracing KA Sharkey, RG Williams, GJ Dockray Gastroenterology 87 (4), 914-921, 1984 | 292 | 1984 |
Characterization of the inflammatory response to proteinase‐activated receptor‐2 (PAR2)‐activating peptides in the rat paw N Vergnolle, MD Hollenberg, KA Sharkey, JL Wallace British journal of pharmacology 127 (5), 1083-1090, 1999 | 264 | 1999 |