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Keith Sharkey PhD, FRSC
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Identification and functional characterization of brainstem cannabinoid CB2 receptors
MD Van Sickle, M Duncan, PJ Kingsley, A Mouihate, P Urbani, K Mackie, ...
Science 310 (5746), 329-332, 2005
19062005
Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome
MD Coates, CR Mahoney, DR Linden, JE Sampson, J Chen, H Blaszyk, ...
Gastroenterology 126 (7), 1657-1664, 2004
9582004
Endocannabinoid signaling at the periphery: 50 years after THC
M Maccarrone, I Bab, T Bíró, GA Cabral, SK Dey, V Di Marzo, JC Konje, ...
Trends in pharmacological sciences 36 (5), 277-296, 2015
7872015
Role for protease activity in visceral pain in irritable bowel syndrome
N Cenac, CN Andrews, M Holzhausen, K Chapman, G Cottrell, ...
The Journal of clinical investigation 117 (3), 636-647, 2007
7162007
Recurrent aphthous ulcers today: a review of the growing knowledge
SS Natah, YT Konttinen, NS Enattah, N Ashammakhi, KA Sharkey, ...
International journal of oral and maxillofacial surgery 33 (3), 221-234, 2004
6232004
Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.
BK Reuter, S Asfaha, A Buret, KA Sharkey, JL Wallace
The Journal of clinical investigation 98 (9), 2076-2085, 1996
5651996
Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway
N Vergnolle, NW Bunnett, KA Sharkey, V Brussee, SJ Compton, EF Grady, ...
Nature medicine 7 (7), 821-826, 2001
5612001
Cannabinoids and the gut: new developments and emerging concepts
AA Izzo, KA Sharkey
Pharmacology & therapeutics 126 (1), 21-38, 2010
5152010
Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation
K Riazi, MA Galic, JB Kuzmiski, W Ho, KA Sharkey, QJ Pittman
Proceedings of the National Academy of Sciences 105 (44), 17151-17156, 2008
4922008
Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis
BD Gulbransen, M Bashashati, SA Hirota, X Gui, JA Roberts, ...
Nature medicine 18 (4), 600-604, 2012
4482012
Novel functional roles for enteric glia in the gastrointestinal tract
BD Gulbransen, KA Sharkey
Nature reviews Gastroenterology & hepatology 9 (11), 625-632, 2012
4082012
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity
JL Wallace, A Bak, W McKnight, S Asfaha, KA Sharkey, WK MacNaughton
Gastroenterology 115 (1), 101-109, 1998
4081998
Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte–endothelium interactions in endotoxemia
MJ Hickey, KA Sharkey, EG Sihota, PH Reinhardt, JD Macmickeng, ...
The FASEB Journal 11 (12), 955-964, 1997
3571997
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation
KL Wright, M Duncan, KA Sharkey
British journal of pharmacology 153 (2), 263-270, 2008
3432008
Inflammatory neuropathies of the enteric nervous system
R De Giorgio, S Guerrini, G Barbara, V Stanghellini, F De Ponti, ...
Gastroenterology 126 (7), 1872-1883, 2004
3382004
Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis
DR Linden, JX Chen, MD Gershon, KA Sharkey, GM Mawe
American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (1 …, 2003
3302003
Activation of colonic mucosal 5-HT4 receptors accelerates propulsive motility and inhibits visceral hypersensitivity
JM Hoffman, K Tyler, SJ MacEachern, OB Balemba, AC Johnson, ...
Gastroenterology 142 (4), 844-854. e4, 2012
3172012
Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret
MD Van Sickle, LD Oland, W Ho, CJ Hillard, KEN Mackie, JS Davison, ...
Gastroenterology 121 (4), 767-774, 2001
3062001
Sensory substance P innervation of the stomach and pancreas: demonstration of capsaicin-sensitive sensory neurons in the rat by combined immunohistochemistry and retrograde tracing
KA Sharkey, RG Williams, GJ Dockray
Gastroenterology 87 (4), 914-921, 1984
2921984
Characterization of the inflammatory response to proteinase‐activated receptor‐2 (PAR2)‐activating peptides in the rat paw
N Vergnolle, MD Hollenberg, KA Sharkey, JL Wallace
British journal of pharmacology 127 (5), 1083-1090, 1999
2641999
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