A reductive aminase from Aspergillus oryzae GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ... Nature chemistry 9 (10), 961-969, 2017 | 336 | 2017 |
Imine reductases (IREDs) J Mangas-Sanchez, SP France, SL Montgomery, GA Aleku, H Man, ... Current opinion in chemical biology 37, 19-25, 2017 | 232 | 2017 |
NAD (P) H‐dependent dehydrogenases for the asymmetric reductive amination of ketones: Structure, mechanism, evolution and application M Sharma, J Mangas‐Sanchez, NJ Turner, G Grogan Advanced Synthesis & Catalysis 359 (12), 2011-2025, 2017 | 121 | 2017 |
Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination JR Marshall, P Yao, SL Montgomery, JD Finnigan, TW Thorpe, RB Palmer, ... Nature chemistry 13 (2), 140-148, 2021 | 114 | 2021 |
Direct alkylation of amines with primary and secondary alcohols through biocatalytic hydrogen borrowing SL Montgomery, J Mangas‐Sanchez, MP Thompson, GA Aleku, ... Angewandte Chemie 129 (35), 10627-10630, 2017 | 111 | 2017 |
Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades JI Ramsden, RS Heath, SR Derrington, SL Montgomery, ... Journal of the American Chemical Society 141 (3), 1201-1206, 2019 | 108 | 2019 |
Identification of novel bacterial members of the imine reductase enzyme family that perform reductive amination SP France, RM Howard, J Steflik, NJ Weise, J Mangas‐Sanchez, ... ChemCatChem 10 (3), 510-514, 2018 | 99 | 2018 |
Chemoenzymatic synthesis of rivastigmine based on lipase-catalyzed processes J Mangas-Sanchez, M Rodriguez-Mata, E Busto, V Gotor-Fernandez, ... The Journal of Organic Chemistry 74 (15), 5304-5310, 2009 | 94 | 2009 |
A mechanism for reductive amination catalyzed by fungal reductive aminases M Sharma, J Mangas-Sanchez, SP France, GA Aleku, SL Montgomery, ... ACS Catalysis 8 (12), 11534-11541, 2018 | 90 | 2018 |
Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation J Mangas-Sánchez, E Busto, V Gotor-Fernández, F Malpartida, V Gotor The Journal of organic chemistry 76 (7), 2115-2122, 2011 | 86 | 2011 |
A generic platform for the immobilisation of engineered biocatalysts MP Thompson, SR Derrington, RS Heath, JL Porter, J Mangas-Sanchez, ... Tetrahedron 75 (3), 327-334, 2019 | 83 | 2019 |
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines SP France, GA Aleku, M Sharma, J Mangas‐Sanchez, RM Howard, ... Angewandte Chemie International Edition 56 (49), 15589-15593, 2017 | 77 | 2017 |
Straightforward synthesis of enantiopure 2, 3-dihydrobenzofurans by a sequential stereoselective biotransformation and chemical intramolecular cyclization J Mangas-Sanchez, E Busto, V Gotor-Fernandez, V Gotor Organic Letters 12 (15), 3498-3501, 2010 | 61 | 2010 |
Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases J Mangas-Sanchez, M Sharma, SC Cosgrove, JI Ramsden, JR Marshall, ... Chemical science 11 (19), 5052-5057, 2020 | 60 | 2020 |
Enantioselective synthesis of chiral vicinal amino alcohols using amine dehydrogenases FF Chen, SC Cosgrove, WR Birmingham, J Mangas-Sanchez, J Citoler, ... ACS Catalysis 9 (12), 11813-11818, 2019 | 60 | 2019 |
Phenolic and antioxidant composition of cider AP Lobo, YD García, JM Sanchez, RR Madrera, BS Valles Journal of food composition and analysis 22 (7-8), 644-648, 2009 | 59 | 2009 |
Kinetic resolution and deracemization of racemic amines using a reductive aminase GA Aleku, J Mangas‐Sanchez, J Citoler, SP France, SL Montgomery, ... ChemCatChem 10 (3), 515-519, 2018 | 56 | 2018 |
One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles TW Thorpe, SP France, S Hussain, JR Marshall, W Zawodny, ... Journal of the American Chemical Society 141 (49), 19208-19213, 2019 | 53 | 2019 |
Highly efficient enzymatic biodiesel production promoted by particle-induced emulsification J Mangas-Sánchez, P Adlercreutz Biotechnology for biofuels 8, 1-8, 2015 | 52 | 2015 |
Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships SL Montgomery, A Pushpanath, RS Heath, JR Marshall, U Klemstein, ... Science advances 6 (21), eaay9320, 2020 | 48 | 2020 |