Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation SE Egan, BW Giddings, MW Brooks, L Buday, AM Sizeland, RA Weinberg Nature 363 (6424), 45-51, 1993 | 1606 | 1993 |
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival M Reedijk, S Odorcic, L Chang, H Zhang, N Miller, DR McCready, ... Cancer research. 65 (18), 8530-7, 2005 | 961 | 2005 |
The pathway to signal achievement. SE Egan, RA Weinberg Nature 365 (6449), 1993 | 813 | 1993 |
A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells. L Buday, SE Egan, PR Viciana, DA Cantrell, J Downward Journal of Biological Chemistry 269 (12), 9019-9023, 1994 | 332 | 1994 |
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15 AS Sengar, W Wang, J Bishay, S Cohen, SE Egan The EMBO journal 18 (5), 1159-71, 1999 | 279 | 1999 |
High-level JAG1 mRNA and protein predict poor outcome in breast cancer BC Dickson, AM Mulligan, H Zhang, G Lockwood, FP O'Malley, SE Egan, ... Modern pathology : an official journal of the United States and Canadian …, 2007 | 277 | 2007 |
Activation of Notch signaling in human colon adenocarcinoma M Reedijk, S Odorcic, H Zhang, R Chetty, C Tennert, BC Dickson, ... International journal of oncology 33 (6), 1223-9, 2008 | 265 | 2008 |
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ... Genome biology 14, 1-16, 2013 | 249 | 2013 |
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1 U Koch, TA Lacombe, D Holland, JL Bowman, BL Cohen, SE Egan, ... Immunity 15 (2), 225-236, 2001 | 238 | 2001 |
Notch signaling in mammary development and oncogenesis. R Callahan, SE Egan Journal of mammary gland biology and neoplasia 9 (2), 145-163, 2004 | 209 | 2004 |
Expression of H-ras Correlates with Metastatic Potential: Evidence for Direct Regulation of the Metastatic Phenotype in 10T1/2 and NIH 3T3 Cells SE Egan, GA McClarty, L Jarolim, JA Wright, I Spiro, G Hager, ... Molecular and cellular biology 7 (2), 830-837, 1987 | 194 | 1987 |
JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. M Reedijk, D Pinnaduwage, BC Dickson, AM Mulligan, H Zhang, SB Bull, ... Breast cancer research and treatment 111 (3), 439-48, 2008 | 192 | 2008 |
Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila HLSEE B. Cohen, A. Bashirullah, Lina Dagnino, C. Campbell, Bill Fisher, C. C ... Nature Genetics 16 (3), 283-288, 1997 | 192 | 1997 |
Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. DT Denhardt, AH Greenberg, SE Egan, RT Hamilton, JA Wright Oncogene 2 (1), 55-59, 1987 | 188 | 1987 |
Notch receptors, partners and regulators: from conserved domains to powerful functions SE Egan, B St-Pierre, CC Leow Protein Modules in Signal Transduction, 273-324, 1998 | 171 | 1998 |
Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation JR Adams, K Xu, JC Liu, NM Agamez, AJ Loch, RG Wong, W Wang, ... Cancer Research 71 (7), 2706-17, 2011 | 167 | 2011 |
Transformation by oncogenes encoding protein kinases induces the metastatic phenotype SE Egan, JA Wright, L Jarolim, K Yanagihara, RH Bassin, AH Greenberg Science 238 (4824), 202-205, 1987 | 164 | 1987 |
Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches JB Tan, K Xu, K Cretegny, I Visan, JS Yuan, SE Egan, CJ Guidos Immunity 30 (2), 254-63, 2009 | 158 | 2009 |
The Hand1, Stra13 and Gcm1 transcription factors override FGF signaling to promote terminal differentiation of trophoblast stem cells. M Hughes, N Dobric, IC Scott, L Su, M Starovic, B St-Pierre, SE Egan, ... Developmental biology 271 (1), 26-37, 2004 | 155 | 2004 |
Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis N Singh, RA Phillips, NN Iscove, SE Egan Experimental hematology 28 (5), 527-534, 2000 | 147 | 2000 |