Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer R Kannaiyan, MK Shanmugam, G Sethi Cancer letters 303 (1), 9-20, 2011 | 368 | 2011 |
Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer MK Shanmugam, R Kannaiyan, G Sethi Nutrition and cancer 63 (2), 161-173, 2011 | 247 | 2011 |
A comprehensive review of protein kinase inhibitors for cancer therapy R Kannaiyan, D Mahadevan Expert review of anticancer therapy 18 (12), 1249-1270, 2018 | 239 | 2018 |
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways R Kannaiyan, KA Manu, L Chen, F Li, P Rajendran, A Subramaniam, ... Apoptosis 16, 1028-1041, 2011 | 177 | 2011 |
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo P Rajendran, F Li, MK Shanmugam, R Kannaiyan, JN Goh, KF Wong, ... Cancer prevention research 5 (4), 631-643, 2012 | 172 | 2012 |
Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse … KS Siveen, N Mustafa, F Li, R Kannaiyan, KS Ahn, AP Kumar, WJ Chng, ... Oncotarget 5 (3), 634, 2014 | 156 | 2014 |
Celastrol inhibits proliferation and induces chemosensitization through down‐regulation of NF‐κB and STAT3 regulated gene products in multiple myeloma cells R Kannaiyan, HS Hay, P Rajendran, F Li, MK Shanmugam, S Vali, ... British journal of pharmacology 164 (5), 1506-1521, 2011 | 149 | 2011 |
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4 KA Manu, MK Shanmugam, P Rajendran, F Li, L Ramachandran, HS Hay, ... Molecular cancer 10, 1-14, 2011 | 146 | 2011 |
Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myeloma MK Shanmugam, KS Ahn, JH Lee, R Kannaiyan, N Mustafa, KA Manu, ... Frontiers in Pharmacology 9, 365, 2018 | 61 | 2018 |
A comparative analysis of tumors and plasma circulating tumor DNA in 145 advanced cancer patients annotated by 3 core cellular processes K Larson, R Kannaiyan, R Pandey, Y Chen, HM Babiker, D Mahadevan Cancers 12 (3), 701, 2020 | 7 | 2020 |
Targeted inhibition of multiple proinflammatory signalling pathways for the prevention and treatment of multiple myeloma R Kannaiyan, R Surana, EM Shin, L Ramachandran, G Sethi, AP Kumar Chapter 5, 93-128, 2012 | 7 | 2012 |
Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma S Sikka, MK Shanmugam, R Kannaiyan, R Surana, EM Shin, AP Kumar, ... Phytochemistry reviews 13, 79-106, 2014 | 5 | 2014 |
IDENTIFICATION OF A NOVEL AGENT THAT CAN SUPPRESS PROLIFERATION, INDUCE APOPTOSIS AND OVERCOME CHEMORESISTANCE IN MULTIPLE MYELOMA R KANNAIYAN | | 2013 |
Celastrol Overcomes Chemoresistance in Vitro and Potentiates the Effect of Bortezomib Against Human Multiple Myeloma in Nude Mice Mode R Kannaiyan, MK Aryan, MK Shanmugam, F Li, G Sethi Blood, The Journal of the American Society of Hematology 120 (21), 5017-5017, 2012 | | 2012 |
Celastrol, a Pentacyclic Tritepenoid Overcomes Chemoresistance Through Downregulation of STAT3 and Nuclear Factor-B-Regulated Antiapoptotic Gene Products in Human Multiple … R Kannaiyan, G Sethi Abstracts of the International Conference of Pharmacology-the 3rd Mainland …, 2010 | | 2010 |