Sydney Coffey
Sydney Coffey
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Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
SA Ament, JR Pearl, JP Cantle, RM Bragg, PJ Skene, SR Coffey, ...
Molecular systems biology 14 (3), e7435, 2018
Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6. Htt Q111/+ model of Huntington’s disease
RM Bragg, SR Coffey, RM Weston, SA Ament, JP Cantle, S Minnig, ...
Scientific reports 7 (1), 1-17, 2017
Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington’s disease
SR Coffey, RM Bragg, S Minnig, SA Ament, JP Cantle, A Glickenhaus, ...
PloS one 12 (4), e0175968, 2017
Huntingtin lowering reduces somatic instability at CAG-expanded loci
SR Coffey, M Andrew, H Ging, J Hamilton, M Flower, M Kovalenko, ...
bioRxiv, 2020
Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntingtons Disease
JR Pearl, AC Shetty, JP Cantle, DE Bergey, RM Bragg, SR Coffey, ...
bioRxiv, 2020
Early detection of apathetic phenotypes in Huntington’s disease knock-in mice using open source tools
S Minnig, RM Bragg, HS Tiwana, WT Solem, WS Hovander, EMS Vik, ...
Scientific reports 8 (1), 1-8, 2018
Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington's disease mutations
S Malaiya, M Cortes-Gutierrez, BR Herb, SR Coffey, SRW Legg, ...
bioRxiv, 2020
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