A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1186 | 2016 |
The yeast lysosome-like vacuole: endpoint and crossroads SC Li, PM Kane Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (4), 650-663, 2009 | 498 | 2009 |
The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase SC Li, TT Diakov, T Xu, M Tarsio, W Zhu, S Couoh-Cardel, LS Weisman, ... Molecular biology of the cell 25 (8), 1251-1262, 2014 | 146 | 2014 |
Plant-derived antifungal agent poacic acid targets β-1, 3-glucan JS Piotrowski, H Okada, F Lu, SC Li, L Hinchman, A Ranjan, DL Smith, ... Proceedings of the National Academy of Sciences 112 (12), E1490-E1497, 2015 | 101 | 2015 |
Functional annotation of chemical libraries across diverse biological processes JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ... Nature Chemical Biology 13 (9), 982-993, 2017 | 84 | 2017 |
Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain Q Dickinson, S Bottoms, L Hinchman, S McIlwain, S Li, CL Myers, ... Microbial Cell Factories 15, 1-13, 2016 | 78 | 2016 |
The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma X Deng, DZ Ewton, S Li, A Naqvi, SE Mercer, S Landas, E Friedman Cancer research 66 (8), 4149-4158, 2006 | 72 | 2006 |
Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation J Serate, D Xie, E Pohlmann, C Donald, M Shabani, L Hinchman, ... Biotechnology for biofuels 8, 1-17, 2015 | 53 | 2015 |
Vacuolar H+-ATPase Works in Parallel with the HOG Pathway To Adapt Saccharomyces cerevisiae Cells to Osmotic Stress SC Li, TT Diakov, JM Rizzo, PM Kane Eukaryotic Cell 11 (3), 282-291, 2012 | 51 | 2012 |
Chemical genomic profiling via barcode sequencing to predict compound mode of action JS Piotrowski, SW Simpkins, SC Li, R Deshpande, SJ McIlwain, IM Ong, ... Chemical Biology: Methods and Protocols, 299-318, 2015 | 39 | 2015 |
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis SY Fung, V Sofiyev, J Schneiderman, AF Hirschfeld, RE Victor, K Woods, ... ACS chemical biology 9 (1), 247-257, 2014 | 38 | 2014 |
BIONIC: biological network integration using convolutions DT Forster, SC Li, Y Yashiroda, M Yoshimura, Z Li, LAV Isuhuaylas, ... Nature Methods 19 (10), 1250-1261, 2022 | 22 | 2022 |
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions SW Simpkins, J Nelson, R Deshpande, SC Li, JS Piotrowski, EH Wilson, ... PLoS computational biology 14 (10), e1006532, 2018 | 20* | 2018 |
MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action J Nelson, SW Simpkins, H Safizadeh, SC Li, JS Piotrowski, H Hirano, ... Bioinformatics 34 (7), 1251-1252, 2018 | 20 | 2018 |
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments SW Simpkins, R Deshpande, J Nelson, SC Li, JS Piotrowski, HN Ward, ... Nature protocols 14 (2), 415-440, 2019 | 18 | 2019 |
Regulation of Vacuolar H+-ATPase Activity by the Cdc42 Effector Ste20 in Saccharomyces cerevisiae M Lin, SC Li, PM Kane, T Höfken Eukaryotic cell 11 (4), 442-451, 2012 | 13 | 2012 |
Improving measures of chemical structural similarity using machine learning on chemical–genetic interactions H Safizadeh, SW Simpkins, J Nelson, SC Li, JS Piotrowski, M Yoshimura, ... Journal of chemical information and modeling 61 (9), 4156-4172, 2021 | 12 | 2021 |
Efficient strategies for screening large-scale genetic interaction networks R Deshpande, J Nelson, SW Simpkins, M Costanzo, JS Piotrowski, SC Li, ... BioRxiv, 159632, 2017 | 10 | 2017 |
Jerveratrum-type steroidal alkaloids inhibit β-1, 6-glucan biosynthesis in fungal cell walls K Kubo, K Itto-Nakama, S Ohnuki, Y Yashiroda, SC Li, H Kimura, ... Microbiology Spectrum 10 (1), e00873-21, 2022 | 9 | 2022 |
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1 R Persaud, SC Li, JD Chao, R Forestieri, E Donohue, AD Balgi, X Zheng, ... Cell Chemical Biology 29 (5), 870-882. e11, 2022 | 6 | 2022 |