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Frans HH  Leenen
Frans HH Leenen
Univ of Ottawa Heart Institute , Ottawa , Canada
Verified email at ottawaheart.ca
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The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to …
Coordinators for the ALLHAT Collaborative Research Group
Jama 288, 2981-2997, 2002
20342002
1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension
S Guideline
J. Hypertens. 17, 151, 1999
1248*1999
Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial …
ALLHAT Collaborative Research Group
Jama 283, 1967-1975, 2000
11062000
Rationale and design for the antihypertensive and lipid lowering treatment to prevent heart attack trial (ALLHAT)
BR Davis, JA Cutler, DJ Gordon, CD Furberg, JT Wright Jr, WC Cushman, ...
American journal of hypertension 9 (4), 342-360, 1996
7681996
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent …
T Antihypertensive, ...
Jama 288 (23), 2998-3007, 2002
6762002
Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril
JT Wright, JK Dunn, JA Cutler, BR Davis, WC Cushman, CE Ford, ...
Jama 293 (13), 1595-1608, 2005
5162005
Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to …
PK Whelton, J Barzilay, WC Cushman, BR Davis, E IIamathi, JB Kostis, ...
Archives of internal medicine 165 (12), 1401-1409, 2005
3792005
Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades
FA McAlister, K Wilkins, M Joffres, FHH Leenen, G Fodor, M Gee, ...
Cmaj 183 (9), 1007-1013, 2011
3512011
Results of the Ontario survey on the prevalence and control of hypertension
FHH Leenen, J Dumais, NH McInnis, P Turton, L Stratychuk, K Nemeth, ...
Cmaj 178 (11), 1441-1449, 2008
3312008
How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension
MP Blaustein, FHH Leenen, L Chen, VA Golovina, JM Hamlyn, TL Pallone, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (5 …, 2012
3182012
1999 Canadian recommendations for the management of hypertension
RD Feldman, N Campbell, P Larochelle, P Bolli, ED Burgess, ...
Cmaj 161 (12 suppl), S1-S17, 1999
2351999
Clinical events in high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid …
FHH Leenen, CE Nwachuku, HR Black, WC Cushman, BR Davis, ...
Hypertension 48 (3), 374-384, 2006
1872006
A solid silver clip for induction of predictable levels of renal hypertension in the rat.
FH Leenen, W de Jong
Journal of applied physiology 31 (1), 142-144, 1971
1661971
17β-Estradiol downregulates tissue angiotensin-converting enzyme and ANG II type 1 receptor in female rats
SA Dean, J Tan, ER O'Brien, FHH Leenen
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005
1632005
Increases in CSF [Na+] precede the increases in blood pressure in Dahl S rats and SHR on a high-salt diet
BS Huang, BN Van Vliet, FHH Leenen
American Journal of Physiology-Heart and Circulatory Physiology 287 (3 …, 2004
1632004
Distribution of epithelial sodium channels and mineralocorticoid receptors in cardiovascular regulatory centers in rat brain
MS Amin, HW Wang, E Reza, SC Whitman, BS Tuana, FHH Leenen
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005
1602005
Both brain angiotensin II and “ouabain” contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake
BS Huang, FHH Leenen
Hypertension 32 (6), 1028-1033, 1998
1561998
The renin-angiotensin system and volume overload-induced cardiac hypertrophy in rats. Effects of angiotensin converting enzyme inhibitor versus angiotensin II receptor blocker.
M Ruzicka, B Yuan, E Harmsen, FH Leenen
Circulation 87 (3), 921-930, 1993
1491993
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
BR Davis, LB Piller, JA Cutler, C Furberg, K Dunn, S Franklin, D Goff, ...
Circulation 113 (18), 2201-2210, 2006
1482006
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring.
FH Leenen, TW Wilson, P Bolli, P Larochelle, M Myers, SP Handa, ...
The Canadian journal of cardiology 13 (10), 914-920, 1997
1461997
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