Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor RJ Andersen, NR Mawji, J Wang, G Wang, S Haile, JK Myung, K Watt, ... Cancer cell 17 (6), 535-546, 2010 | 618 | 2010 |
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, ... Cell 126 (3), 611-625, 2006 | 569 | 2006 |
Metabolites of the marine prosobranch mollusk Lamellaria sp RJ Andersen, DJ Faulkner, CH He, GD Van Duyne, J Clardy Journal of the American Chemical Society 107 (19), 5492-5495, 1985 | 424 | 1985 |
Novel natural products from soil DNA libraries in a streptomycete host GYS Wang, E Graziani, B Waters, W Pan, X Li, J McDermott, G Meurer, ... Organic letters 2 (16), 2401-2404, 2000 | 385 | 2000 |
An androgen receptor N-terminal domain antagonist for treating prostate cancer JK Myung, CA Banuelos, JG Fernandez, NR Mawji, J Wang, AH Tien, ... The Journal of clinical investigation 123 (7), 2948-2960, 2013 | 355 | 2013 |
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds CH Ho, L Magtanong, SL Barker, D Gresham, S Nishimura, P Natarajan, ... Nature biotechnology 27 (4), 369-377, 2009 | 332 | 2009 |
Papuamides A−D, HIV-Inhibitory and Cytotoxic Depsipeptides from the Sponges Theonella mirabilis and Theonella swinhoei Collected in Papua New Guinea PW Ford, KR Gustafson, TC McKee, N Shigematsu, LK Maurizi, ... Journal of the American Chemical Society 121 (25), 5899-5909, 1999 | 305 | 1999 |
Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei Gray ED De Silva, DE Williams, RJ Andersen, H Klix, CFB Holmes, TM Allen Tetrahedron letters 33 (12), 1561-1564, 1992 | 290 | 1992 |
Effects of nutrient limitation on toxin production and composition in the marine dinoflagellate Protogonyaulax tamarensis GL Boyer, JJ Sullivan, RJ Andersen, PJ Harrison, FJR Taylor Marine Biology 96, 123-128, 1987 | 288 | 1987 |
Variation in paralytic shellfish toxin composition within the Protogonyaulax tamaronsis/catenella species complex; red tide dinoflagellates AD Cembella, JJ Sullivan, GL Boyer, FJR Taylor, RJ Andersen Biochemical systematics and ecology 15 (2), 171-186, 1987 | 276 | 1987 |
Chemical and biological evidence links microcystins to salmon ‘netpen liver disease’ RJ Andersen, HA Luu, DZX Chen, CFB Holmes, ML Kent, M Le Blanc, ... Toxicon 31 (10), 1315-1323, 1993 | 273 | 1993 |
The search for novel human pancreatic α‐amylase inhibitors: high‐throughput screening of terrestrial and marine natural product extracts CA Tarling, K Woods, R Zhang, HC Brastianos, GD Brayer, RJ Andersen, ... ChemBioChem 9 (3), 433-438, 2008 | 272 | 2008 |
Massetolides A− H, antimycobacterial cyclic depsipeptides produced by two pseudomonads isolated from marine habitats J Gerard, R Lloyd, T Barsby, P Haden, MT Kelly, RJ Andersen Journal of natural products 60 (3), 223-229, 1997 | 239 | 1997 |
Autotoxic antibiotic production by a marine Chromobacterium RJ Andersen, MS Wolfe, DJ Faulkner Marine Biology 27, 281-285, 1974 | 230 | 1974 |
Molecular mechanisms underlying the interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases M Craig, HA Luu, TL McCready, CFB Holmes, D Williams, RJ Andersen Biochemistry and cell biology 74 (4), 569-578, 1996 | 217 | 1996 |
Brominated bis (indole) alkaloids from the marine sponge Hexadella sp SA Morris, RJ Andersen Tetrahedron 46 (3), 715-720, 1990 | 215 | 1990 |
The adsorption of microcystin-LR by natural clay particles RJ Morris, DE Williams, HA Luu, CFB Holmes, RJ Andersen, SE Calvert Toxicon 38 (2), 303-308, 2000 | 210 | 2000 |
Bioaccumulation and clearance of microcystins from salt water mussels, Mytilus edulis, and in vivo evidence for covalently bound microcystins in mussel tissues DE Williams, SC Dawe, ML Kent, RJ Andersen, M Craig, CFB Holmes Toxicon 35 (11), 1617-1625, 1997 | 208 | 1997 |
Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation HJ Anderson, JE Coleman, RJ Andersen, M Roberge Cancer chemotherapy and pharmacology 39, 223-226, 1996 | 208 | 1996 |
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action K Baetz, L McHardy, K Gable, T Tarling, D Rebérioux, J Bryan, ... Proceedings of the National Academy of Sciences 101 (13), 4525-4530, 2004 | 205 | 2004 |