| Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways L Larue, A Bellacosa Oncogene 24 (50), 7443-7454, 2005 | 1517 | 2005 |
| E-cadherin null mutant embryos fail to form a trophectoderm epithelium. L Larue, M Ohsugi, J Hirchenhain, R Kemler Proceedings of the National Academy of Sciences 91 (17), 8263-8267, 1994 | 1176 | 1994 |
| Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair S Cortellino, J Xu, M Sannai, R Moore, E Caretti, A Cigliano, M Le Coz, ... Cell 146 (1), 67-79, 2011 | 969 | 2011 |
| Lack of β-catenin affects mouse development at gastrulation H Haegel, L Larue, M Ohsugi, L Fedorov, K Herrenknecht, R Kemler Development 121 (11), 3529-3537, 1995 | 935 | 1995 |
| The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines SJ Grille, A Bellacosa, J Upson, AJ Klein-Szanto, F Van Roy, W Lee-Kwon, ... Cancer research 63 (9), 2172-2178, 2003 | 848 | 2003 |
| Mitf regulation of Dia1 controls melanoma proliferation and invasiveness S Carreira, J Goodall, L Denat, M Rodriguez, P Nuciforo, KS Hoek, ... Genes & development 20 (24), 3426-3439, 2006 | 677 | 2006 |
| Oncogenic Braf induces melanocyte senescence and melanoma in mice N Dhomen, JS Reis-Filho, S da Rocha Dias, R Hayward, K Savage, ... Cancer cell 15 (4), 294-303, 2009 | 670 | 2009 |
| MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer N Fujita, DL Jaye, M Kajita, C Geigerman, CS Moreno, PA Wade Cell 113 (2), 207-219, 2003 | 659 | 2003 |
| Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition S Julien, I Puig, E Caretti, J Bonaventure, L Nelles, F Van Roy, ... Oncogene 26 (53), 7445-7456, 2007 | 555 | 2007 |
| Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression S Carreira, J Goodall, I Aksan, SA La Rocca, MD Galibert, L Denat, ... Nature 433 (7027), 764-769, 2005 | 466 | 2005 |
| A role for cadherins in tissue formation L Larue, C Antos, S Butz, O Huber, V Delmas, M Dominis, R Kemler Development 122 (10), 3185-3194, 1996 | 464 | 1996 |
| Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells MJ Barbera, I Puig, D Domínguez, S Julien-Grille, S Guaita-Esteruelas, ... Oncogene 23 (44), 7345-7354, 2004 | 414 | 2004 |
| β-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development V Delmas, F Beermann, S Martinozzi, S Carreira, J Ackermann, ... Genes & development 21 (22), 2923-2935, 2007 | 377 | 2007 |
| MDM4 is a key therapeutic target in cutaneous melanoma A Gembarska, F Luciani, C Fedele, EA Russell, M Dewaele, S Villar, ... Nature medicine 18 (8), 1239-1247, 2012 | 356 | 2012 |
| IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition OG Morali, V Delmas, R Moore, C Jeanney, JP Thiery, L Larue Oncogene 20 (36), 4942-4950, 2001 | 314 | 2001 |
| The WNT/Beta-catenin pathway in melanoma L Larue, V Delmas Front Biosci 11 (1), 733-42, 2006 | 311 | 2006 |
| Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells M Moriyama, M Osawa, SS Mak, T Ohtsuka, N Yamamoto, H Han, ... The Journal of cell biology 173 (3), 333-339, 2006 | 293 | 2006 |
| Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis D Javelaud, KS Mohammad, CR McKenna, P Fournier, F Luciani, ... Cancer research 67 (5), 2317-2324, 2007 | 228 | 2007 |
| A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway C Praetorius, C Grill, SN Stacey, AM Metcalf, DU Gorkin, KC Robinson, ... Cell 155 (5), 1022-1033, 2013 | 223 | 2013 |
| Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor–negative melanoma … J Goodall, S Carreira, L Denat, D Kobi, I Davidson, P Nuciforo, RA Sturm, ... Cancer research 68 (19), 7788-7794, 2008 | 223 | 2008 |
Eirikur SteingrimssonProfessor, Faculty of Medicine, University of IcelandVerified email at hi.is
