| New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage A Petit, F Bihel, CA da Costa, O Pourquié, F Checler, JL Kraus Nature cell biology 3 (5), 507-511, 2001 | 248 | 2001 |
| The initial substrate-binding site of γ-secretase is located on presenilin near the active site AY Kornilova, F Bihel, C Das, MS Wolfe Proceedings of the National Academy of Sciences 102 (9), 3230-3235, 2005 | 239 | 2005 |
| Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors K Elhabazi, JP Humbert, I Bertin, M Schmitt, F Bihel, JJ Bourguignon, ... Neuropharmacology 75, 164-171, 2013 | 113 | 2013 |
| 6-endo-dig Cyclization of heteroarylesters to alkynes promoted by Lewis acid catalyst in the presence of Brønsted acid M Hellal, JJ Bourguignon, FJJ Bihel Tetrahedron Letters 49 (1), 62-65, 2008 | 100 | 2008 |
| Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments K Elhabazi, JM Trigo, C Mollereau, L Moulédous, JM Zajac, F Bihel, ... British journal of pharmacology 165 (2), 424-435, 2012 | 91 | 2012 |
| The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction C Klein, C Patte-Mensah, O Taleb, JJ Bourguignon, M Schmitt, F Bihel, ... Neuropharmacology 70, 254-260, 2013 | 88 | 2013 |
| t-BuXPhos: a highly efficient ligand for Buchwald–Hartwig coupling in water P Wagner, M Bollenbach, C Doebelin, F Bihel, JJ Bourguignon, C Salomé, ... Green Chemistry 16 (9), 4170-4178, 2014 | 80 | 2014 |
| New 2-bromomethyl-8-substituted-benzo [c] chromen-6-ones. Synthesis and biological properties C Garino, F Bihel, N Pietrancosta, Y Laras, G Quelever, I Woo, P Klein, ... Bioorganic & medicinal chemistry letters 15 (1), 135-138, 2005 | 76 | 2005 |
| RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions R Quillet, S Ayachi, F Bihel, K Elhabazi, B Ilien, F Simonin Pharmacology & therapeutics 160, 84-132, 2016 | 69 | 2016 |
| Discovery of a Subnanomolar Helical d-Tridecapeptide Inhibitor of γ-Secretase F Bihel, C Das, MJ Bowman, MS Wolfe Journal of medicinal chemistry 47 (16), 3931-3933, 2004 | 66 | 2004 |
| Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease F Bihel, G Quéléver, H Lelouard, A Petit, CA da Costa, O Pourquié, ... Bioorganic & medicinal chemistry 11 (14), 3141-3152, 2003 | 65 | 2003 |
| TSPO ligands boost mitochondrial function and pregnenolone synthesis I Lejri, A Grimm, F Hallé, M Abarghaz, C Klein, M Maitre, M Schmitt, ... Journal of Alzheimer's Disease 72 (4), 1045-1058, 2019 | 60 | 2019 |
| Evolution of coumaroyl conjugate 3‐hydroxylases in land plants: lignin biosynthesis and defense AV Alber, H Renault, A Basilio‐Lopes, JE Bassard, Z Liu, P Ullmann, ... The Plant Journal 99 (5), 924-936, 2019 | 58 | 2019 |
| Buchwald–Hartwig reactions in water using surfactants C Salomé, P Wagner, M Bollenbach, F Bihel, JJ Bourguignon, M Schmitt Tetrahedron 70 (21), 3413-3421, 2014 | 55 | 2014 |
| Fully regiocontrolled polyarylation of pyridine C Doebelin, P Wagner, F Bihel, N Humbert, CA Kenfack, Y Mely, ... The journal of Organic Chemistry 79 (3), 908-918, 2014 | 51 | 2014 |
| New 3‘-Azido-3‘-deoxythymidin-5‘-yl O-(ω-Hydroxyalkyl) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation P Vlieghe, F Bihel, T Clerc, C Pannecouque, M Witvrouw, E De Clercq, ... Journal of medicinal chemistry 44 (5), 777-786, 2001 | 49 | 2001 |
| A bifunctional-biased mu-opioid agonist–neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects AD La Rochelle, K Guillemyn, M Dumitrascuta, C Martin, V Utard, ... Pain 159 (9), 1705-1718, 2018 | 42 | 2018 |
| d‐Glucose: An Efficient Reducing Agent for a Copper(II)‐Mediated Arylation of Primary Amines in Water M Bollenbach, P Wagner, PGV Aquino, JJ Bourguignon, F Bihel, ... ChemSusChem 9 (22), 3244-3249, 2016 | 42 | 2016 |
| The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis G Leva, C Klein, J Benyounes, F Hallé, F Bihel, N Collongues, J De Seze, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 41 | 2017 |
| Design of potential new HIV protease inhibitors: enantioconvergent synthesis of new pyrrolidin-3-ol, and pyrrolidin-3-one peptide conjugates J Courcambeck, F Bihel, C De Michelis, G Quéléver, JL Kraus Journal of the Chemical Society, Perkin Transactions 1, 1421-1430, 2001 | 40 | 2001 |
