| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1693 | 2015 |
| Proximal events in Wnt signal transduction S Angers, RT Moon Nature Reviews Molecular Cell Biology 10 (7), 468-477, 2009 | 1399 | 2009 |
| Detection of β2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET) S Angers, A Salahpour, E Joly, S Hilairet, D Chelsky, M Dennis, M Bouvier Proceedings of the National Academy of Sciences 97 (7), 3684, 2000 | 1053 | 2000 |
| Gli proteins in development and disease C Hui, S Angers Annual review of cell and developmental biology 27 (1), 513-537, 2011 | 831 | 2011 |
| Wnt signaling in development and tissue homeostasis Z Steinhart, S Angers Development 145 (11), dev146589, 2018 | 778 | 2018 |
| Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery S Angers, T Li, X Yi, MJ MacCoss, RT Moon, N Zheng Nature 443 (7111), 590-593, 2006 | 772 | 2006 |
| Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function S Angers, A Salahpour, M Bouvier Annual review of pharmacology and toxicology 42 (1), 409-435, 2002 | 750 | 2002 |
| High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies JY Youn, WH Dunham, SJ Hong, JDR Knight, M Bashkurov, GI Chen, ... Molecular cell 69 (3), 517-532. e11, 2018 | 706 | 2018 |
| Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants JP Morello, A Salahpour, A Laperrière, V Bernier, MF Arthus, M Lonergan, ... The Journal of clinical investigation 105 (7), 887-895, 2000 | 669 | 2000 |
| β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors M Azzi, PG Charest, S Angers, G Rousseau, T Kohout, M Bouvier, ... Proceedings of the National Academy of Sciences 100 (20), 11406-11411, 2003 | 652 | 2003 |
| Quantitative assessment of β1-and β2-adrenergic receptor homo-and heterodimerization by bioluminescence resonance energy transfer JF Mercier, A Salahpour, S Angers, A Breit, M Bouvier Journal of Biological Chemistry 277 (47), 44925, 2002 | 606 | 2002 |
| Visualization of a short-range Wnt gradient in the intestinal stem-cell niche HF Farin, I Jordens, MH Mosa, O Basak, J Korving, DVF Tauriello, ... Nature 530 (7590), 340-343, 2016 | 583 | 2016 |
| Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling MB Major, ND Camp, JD Berndt, XH Yi, SJ Goldenberg, C Hubbert, ... Science 316 (5827), 1043, 2007 | 509 | 2007 |
| The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation S Angers, CJ Thorpe, TL Biechele, SJ Goldenberg, N Zheng, ... Nature cell biology 8 (4), 348-357, 2006 | 463 | 2006 |
| YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation A Fernandez-L, PA Northcott, J Dalton, C Fraga, D Ellison, S Angers, ... Genes & development 23 (23), 2729-2741, 2009 | 443 | 2009 |
| Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer MA Ayoub, C Couturier, E Lucas-Meunier, S Angers, P Fossier, M Bouvier, ... Journal of Biological Chemistry 277 (24), 21522, 2002 | 396 | 2002 |
| Glutamate transporter coupling to Na, K-ATPase EM Rose, JCP Koo, JE Antflick, SM Ahmed, S Angers, DR Hampson The Journal of Neuroscience 29 (25), 8143-8155, 2009 | 386 | 2009 |
| Homodimerization of the β2-adrenergic receptor as a prerequisite for cell surface targeting A Salahpour, S Angers, JF Mercier, M Lagacé, S Marullo, M Bouvier Journal of Biological Chemistry 279 (32), 33390-33397, 2004 | 383 | 2004 |
| CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ... Nature 559 (7713), 285-289, 2018 | 374 | 2018 |
| Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017 | 327 | 2017 |
Michel BouvierProfessor of Biochem. and Mol. Med., IRIC, Univ. de MontréalVerified email at umontreal.ca
