| Steroid sulfatase inhibitors: a review covering the promising 2000–2010 decade R Maltais, D Poirier Steroids 76 (10-11), 929-948, 2011 | 90 | 2011 |
| Steroid sulfatase inhibitors D Poirier, LC Ciobanu, R Maltais Expert Opinion on Therapeutic Patents 9 (8), 1083-1099, 1999 | 83 | 1999 |
| Synthesis and optimization of a new family of type 3 17β-hydroxysteroid dehydrogenase inhibitors by parallel liquid-phase chemistry R Maltais, V Luu-The, D Poirier Journal of medicinal chemistry 45 (3), 640-653, 2002 | 78 | 2002 |
| Solid-phase synthesis of hydroxysteroid derivatives using the diethylsilyloxy linker R Maltais, MR Tremblay, D Poirier Journal of Combinatorial Chemistry 2 (6), 604-614, 2000 | 61 | 2000 |
| Impact of estradiol structural modifications (18-methyl and/or 17-hydroxy inversion of configuration) on the in vitro and in vivo estrogenic activity D Ayan, J Roy, R Maltais, D Poirier The Journal of steroid biochemistry and molecular biology 127 (3-5), 324-330, 2011 | 60 | 2011 |
| A new nonestrogenic steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type I blocks the estrogen-dependent breast cancer tumor growth induced by estrone D Ayan, R Maltais, J Roy, D Poirier Molecular cancer therapeutics 11 (10), 2096-2104, 2012 | 59 | 2012 |
| Steroids and combinatorial chemistry R Maltais, MR Tremblay, LC Ciobanu, D Poirier Journal of combinatorial chemistry 6 (4), 443-456, 2004 | 56 | 2004 |
| Discovery of a Non-Estrogenic Irreversible Inhibitor of 17β-Hydroxysteroid Dehydrogenase Type 1 from 3-Substituted-16β-(m-carbamoylbenzyl)-estradiol Derivatives R Maltais, D Ayan, A Trottier, X Barbeau, P Lagüe, JE Bouchard, ... Journal of medicinal chemistry 57 (1), 204-222, 2014 | 43 | 2014 |
| Identification of a 17β‐Hydroxysteroid Dehydrogenase Type 10 Steroidal Inhibitor: A Tool to Investigate the Role of Type 10 in Alzheimer’s Disease and Prostate Cancer D Ayan, R Maltais, D Poirier ChemMedChem 7 (7), 1181-1184, 2012 | 37 | 2012 |
| Chemical synthesis, cytotoxicity, selectivity and bioavailability of 5α-androstane-3α, 17β-diol derivatives D Ayan, R Maltais, A Hospital, D Poirier Bioorganic & medicinal chemistry 22 (21), 5847-5859, 2014 | 36 | 2014 |
| Development of 3-substituted-androsterone derivatives as potent inhibitors of 17β-hydroxysteroid dehydrogenase type 3 R Maltais, MA Fournier, D Poirier Bioorganic & medicinal chemistry 19 (15), 4652-4668, 2011 | 35 | 2011 |
| Parallel solid-phase synthesis of 3β-peptido-3α-hydroxy-5α-androstan-17-one derivatives for inhibition of type 3 17β-hydroxysteroid dehydrogenase R Maltais, V Luu-The, D Poirier Bioorganic & medicinal chemistry 9 (12), 3101-3111, 2001 | 35* | 2001 |
| Targeting cytochrome P450 (CYP) 1B1 enzyme with four series of A-ring substituted estrane derivatives: design, synthesis, inhibitory activity, and selectivity R Dutour, J Roy, F Cortés-Benítez, R Maltais, D Poirier Journal of Medicinal Chemistry 61 (20), 9229-9245, 2018 | 31 | 2018 |
| A novel aminosteroid of the 5α-androstane-3α, 17β-diol family induces cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells H Jegham, J Roy, R Maltais, S Desnoyers, D Poirier Investigational new drugs 30, 176-185, 2012 | 31 | 2012 |
| Libraries of 2β-(N-substituted piperazino)-5α-androstane-3α, 17β-diols: chemical synthesis and cytotoxic effects on human leukemia HL-60 cells and on normal … J Roy, R Maltais, H Jegham, D Poirier Molecular diversity 15, 317-339, 2011 | 31 | 2011 |
| Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties C Ouellet, R Maltais, É Ouellet, X Barbeau, P Lagüe, D Poirier European Journal of Medicinal Chemistry 119, 169-182, 2016 | 30 | 2016 |
| A solution-phase combinatorial parallel synthesis of 3β-amido-3α-hydroxy-5α-androstane-17-ones D Poirier Tetrahedron letters 39 (24), 4151-4154, 1998 | 27 | 1998 |
| Design of a Mestranol 2‐N‐Piperazino‐Substituted Derivative Showing Potent and Selective in vitro and in vivo Activities in MCF‐7 Breast Cancer Models M Perreault, R Maltais, J Roy, R Dutour, D Poirier ChemMedChem 12 (2), 177-182, 2017 | 26 | 2017 |
| Chemical synthesis, NMR analysis and evaluation on a cancer xenograft model (HL-60) of the aminosteroid derivative RM-133 R Maltais, A Hospital, A Delhomme, J Roy, D Poirier Steroids 82, 68-76, 2014 | 26 | 2014 |
| The sulfamate functional group as a new anchor for solid-phase organic synthesis LC Ciobanu, R Maltais, D Poirier Organic Letters 2 (4), 445-448, 2000 | 26 | 2000 |
