| High frequency of mutations of the PIK3CA gene in human cancers Y Samuels, Z Wang, A Bardelli, N Silliman, J Ptak, S Szabo, H Yan, ... Science 304 (5670), 554-554, 2004 | 4283 | 2004 |
| Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ... Cell 161 (7), 1681-1696, 2015 | 2652 | 2015 |
| Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells PF Robbins, YC Lu, M El-Gamil, YF Li, C Gross, J Gartner, JC Lin, JK Teer, ... Nature medicine 19 (6), 747, 2013 | 1181 | 2013 |
| Mutant PIK3CA promotes cell growth and invasion of human cancer cells Y Samuels, LA Diaz, O Schmidt-Kittler, JM Cummins, L DeLong, I Cheong, ... Cancer cell 7 (6), 561-573, 2005 | 1078 | 2005 |
| ASPP proteins specifically stimulate the apoptotic function of p53 Y Samuels-Lev, DJ O'Connor, D Bergamaschi, G Trigiante, JK Hsieh, ... Molecular cell 8 (4), 781-794, 2001 | 932 | 2001 |
| The PIK3CA gene is mutated with high frequency in human breast cancers KE Bachman, P Argani, Y Samuels, N Silliman, J Ptak, S Szabo, ... Cancer biology & therapy 3 (8), 772-775, 2004 | 880 | 2004 |
| Mutations in a signalling pathway DW Parsons, TL Wang, Y Samuels, A Bardelli, JM Cummins, L DeLong, ... Nature 436 (7052), 792-792, 2005 | 695 | 2005 |
| Oncogenic PI3K and its role in cancer Y Samuels, K Ericson Current opinion in oncology 18 (1), 77-82, 2006 | 675 | 2006 |
| The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations CH Huang, D Mandelker, O Schmidt-Kittler, Y Samuels, VE Velculescu, ... Science 318 (5857), 1744-1748, 2007 | 640 | 2007 |
| Oncogenic mutations of PIK3CA in human cancers Y Samuels, VE Velculescu Cell cycle 3 (10), 1221-1224, 2004 | 604 | 2004 |
| Exome sequencing identifies GRIN2A as frequently mutated in melanoma X Wei, V Walia, JC Lin, JK Teer, TD Prickett, J Gartner, S Davis, ... Nature genetics 43 (5), 442-446, 2011 | 582 | 2011 |
| Mutational inactivation of STAG2 causes aneuploidy in human cancer DA Solomon, T Kim, LA Diaz-Martinez, J Fair, AG Elkahloun, BT Harris, ... Science 333 (6045), 1039-1043, 2011 | 547 | 2011 |
| iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human D Bergamaschi, Y Samuels, NJ O'Neil, G Trigiante, T Crook, JK Hsieh, ... Nature genetics 33 (2), 162-167, 2003 | 517 | 2003 |
| Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas DK Broderick, C Di, TJ Parrett, YR Samuels, JM Cummins, RE McLendon, ... Cancer research 64 (15), 5048-5050, 2004 | 441 | 2004 |
| Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions YC Lu, X Yao, JS Crystal, YF Li, M El-Gamil, C Gross, L Davis, ME Dudley, ... Clinical Cancer Research 20 (13), 3401-3410, 2014 | 438 | 2014 |
| Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4 TD Prickett, NS Agrawal, X Wei, KE Yates, JC Lin, JR Wunderlich, ... Nature genetics 41 (10), 1127-1132, 2009 | 415 | 2009 |
| Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response CN Spencer, JL McQuade, V Gopalakrishnan, JA McCulloch, M Vetizou, ... Science 374 (6575), 1632-1640, 2021 | 407 | 2021 |
| Extreme vulnerability of IDH1 mutant cancers to NAD+ depletion K Tateishi, H Wakimoto, AJ Iafrate, S Tanaka, F Loebel, N Lelic, ... Cancer cell 28 (6), 773-784, 2015 | 406 | 2015 |
| Oncogenic mutations of PIK3CA in human cancers Y Samuels, T Waldman Phosphoinositide 3-kinase in Health and Disease: Volume 2, 21-41, 2011 | 343 | 2011 |
| iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53 D Bergamaschi, Y Samuels, A Sullivan, M Zvelebil, H Breyssens, A Bisso, ... Nature genetics 38 (10), 1133-1141, 2006 | 335 | 2006 |
