A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), 2016 | 1203 | 2016 |
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 225 | 2020 |
Coculture of marine invertebrate-associated bacteria and interdisciplinary technologies enable biosynthesis and discovery of a new antibiotic, keyicin N Adnani, MG Chevrette, SN Adibhatla, F Zhang, Q Yu, DR Braun, ... ACS chemical biology 12 (12), 3093-3102, 2017 | 121 | 2017 |
Erratum: Functional annotation of chemical libraries across diverse biological processes JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ... Nature chemical biology 13 (12), 1286-1286, 2017 | 84* | 2017 |
Functional annotation of chemical libraries across diverse biological processes JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ... Nature chemical biology 13 (9), 982, 2017 | 84 | 2017 |
Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing JS Bloom, EM Jones, M Gasperini, NB Lubock, L Sathe, C Munugala, ... medRxiv, 2020 | 50 | 2020 |
Targeted three-dimensional liquid chromatography: A versatile tool for quantitative trace analysis in complex matrices SW Simpkins, JW Bedard, SR Groskreutz, MM Swenson, TE Liskutin, ... Journal of Chromatography A 1217 (49), 7648-7660, 2010 | 48 | 2010 |
Chemical genomic profiling via barcode sequencing to predict compound mode of action JS Piotrowski, SW Simpkins, SC Li, R Deshpande, SJ McIlwain, IM Ong, ... Chemical Biology: Methods and Protocols, 299-318, 2015 | 40 | 2015 |
Accumulation of heme biosynthetic intermediates contributes to the antibacterial action of the metalloid tellurite EH Morales, CA Pinto, R Luraschi, CM Muñoz-Villagrán, FA Cornejo, ... Nature communications 8 (1), 1-12, 2017 | 39 | 2017 |
Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin TP Wyche, RFR Alvarenga, JS Piotrowski, MN Duster, SR Warrack, ... ACS Chemical Biology 12 (9), 2287-2295, 2017 | 27 | 2017 |
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions SW Simpkins, J Nelson, R Deshpande, SC Li, JS Piotrowski, EH Wilson, ... PLOS Computational Biology 14 (10), e1006532, 2018 | 20* | 2018 |
MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action J Nelson, SW Simpkins, H Safizadeh, S Li, J Piotrowski, H Hirano, ... bioRxiv, 112854, 2017 | 20 | 2017 |
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments SW Simpkins, R Deshpande, J Nelson, SC Li, JS Piotrowski, HN Ward, ... Nature protocols 14 (2), 415-440, 2019 | 18 | 2019 |
A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter JR Davison, KM Lohith, X Wang, K Bobyk, SR Mandadapu, SL Lee, ... Antimicrobial Agents and Chemotherapy 61 (6), e02635-16, 2017 | 18 | 2017 |
Reliable and accurate diagnostics from highly multiplexed sequencing assays AS Booeshaghi, NB Lubock, AR Cooper, SW Simpkins, JS Bloom, ... Scientific reports 10 (1), 1-7, 2020 | 17* | 2020 |
Efficient strategies for screening large-scale genetic interaction networks R Deshpande, J Nelson, SW Simpkins, M Costanzo, JS Piotrowski, SC Li, ... bioRxiv, 159632, 2017 | 10 | 2017 |
Contamination of deconjugation enzymes derived from Helix pomatia with the plant bioactive compounds 3, 3′-diindolylmethane, 5-methoxypsoralen, and 8-methoxypsoralen CE Ainslie-Waldman, SW Simpkins, P Upadhyaya, SG Carmella, ... Food and chemical toxicology 62, 188-193, 2013 | 6 | 2013 |
Integrating yeast chemical genomics and mammalian cell pathway analysis F Zhou, SC Li, Y Zhu, W Guo, L Shao, J Nelson, S Simpkins, D Yang, ... Acta Pharmacologica Sinica 40 (9), 1245-1255, 2019 | 5 | 2019 |
Improving prediction of compound function from chemical structure using chemical-genetic networks H Safizadeh, SW Simpkins, J Nelson, CL Myers bioRxiv, 112698, 2017 | 4 | 2017 |
Publisher Correction: Integrating yeast chemical genomics and mammalian cell pathway analysis. FL Zhou, SC Li, Y Zhu, WJ Guo, LJ Shao, J Nelson, S Simpkins, DH Yang, ... Acta Pharmacologica Sinica 41 (5), 729, 2020 | | 2020 |