| Tumour necrosis factor signalling in health and disease J Holbrook, S Lara-Reyna, H Jarosz-Griffiths, MF McDermott F1000Research 8, 2019 | 311 | 2019 |
| Neurodegenerative disease and the NLRP3 inflammasome JA Holbrook, HH Jarosz-Griffiths, E Caseley, S Lara-Reyna, JA Poulter, ... Frontiers in pharmacology 12, 643254, 2021 | 126 | 2021 |
| Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis HH Jarosz-Griffiths, T Scambler, CH Wong, S Lara-Reyna, J Holbrook, ... Elife 9, e54556, 2020 | 97 | 2020 |
| ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis T Scambler, HH Jarosz-Griffiths, S Lara-Reyna, S Pathak, C Wong, ... Elife 8, e49248, 2019 | 90 | 2019 |
| Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations S Lara-Reyna, J Holbrook, HH Jarosz-Griffiths, D Peckham, ... Cellular and Molecular Life Sciences 77 (22), 4485-4503, 2020 | 55 | 2020 |
| Metabolic reprograming of cystic fibrosis macrophages via the IRE1α arm of the unfolded protein response results in exacerbated inflammation S Lara-Reyna, T Scambler, J Holbrook, C Wong, HH Jarosz-Griffiths, ... Frontiers in immunology 10, 460242, 2019 | 49 | 2019 |
| TNF receptor signalling in autoinflammatory diseases HH Jarosz-Griffiths, J Holbrook, S Lara-Reyna, MF McDermott International immunology 31 (10), 639-648, 2019 | 47 | 2019 |
| Inflammasome activation: from molecular mechanisms to autoinflammation S Lara‐Reyna, EA Caseley, J Topping, F Rodrigues, J Jimenez Macias, ... Clinical & Translational Immunology 11 (7), e1404, 2022 | 18 | 2022 |
| NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ... Cell reports 42 (5), 2023 | 12 | 2023 |
| Jarosz-Gri ths H, McDermott M J Holbrook, S Lara-Reyna Tumour necrosis factor signalling in health and disease. F1000Res 8, F1000, 2019 | 9 | 2019 |
| An atypical autoinflammatory disease due to an LRR domain NLRP3 mutation enhancing binding to NEK7 EA Caseley, S Lara-Reyna, JA Poulter, J Topping, C Carter, F Nadat, ... Journal of Clinical Immunology, 1-13, 2022 | 8 | 2022 |
| PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection D Fisch, MM Pfleiderer, E Anastasakou, GM Mackie, F Wendt, X Liu, ... Science 382 (6666), eadg2253, 2023 | 6 | 2023 |
| Identification of critical Transcriptomic Signaling pathways in patients with H syndrome and Rosai-Dorfman Disease S Lara-Reyna, JA Poulter, EJR Vasconcelos, M Kacar, MF McDermott, ... Journal of clinical immunology 41, 441-457, 2021 | 6 | 2021 |
| Evidence of B cell clonality and investigation into properties of the IgM in patients with Schnitzler syndrome S Pathak, D Rowczenio, S Lara-Reyna, M Kacar, R Owen, G Doody, ... Frontiers in immunology 11, 569006, 2020 | 6 | 2020 |
| Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen CU Onyishi, GE Desanti, AL Wilkinson, S Lara-Reyna, EM Frickel, G Fejer, ... Nature Communications 14 (1), 4895, 2023 | 5 | 2023 |
| Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome M Zatyka, TR Rosenstock, C Sun, AM Palhegyi, GW Hughes, ... Stem Cell Reports 18 (5), 1090-1106, 2023 | 5 | 2023 |
| Tumour necrosis factor signalling in health and disease. F1000Res. 2019; 8: F1000 Faculty Rev-111 J Holbrook, S Lara-Reyna, H Jarosz-Griffiths, M McDermott | 5 | |
| Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon JD O'Neil, OO Bolimowska, SA Clayton, T Tang, KK Daley, S Lara-Reyna, ... Frontiers in Immunology 14, 1190261, 2023 | 2 | 2023 |
| Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in cystic fibrosis T Scambler, HH Jarosz-Griffiths, S Lara-Reyna, S Pathak, C Wong, ... bioRxiv, 458208, 2018 | 2 | 2018 |
| Regulation of the unfolded protein response in disease: cellular stress and microRNAs S Lara-Reyna, T Scambler, J Holbrook, HH Jarosz-Griffiths, D Peckham, ... Current Immunology Reviews 14 (1), 3-14, 2018 | 1 | 2018 |
Professor Daniel PeckhamUniversity of Leeds and Leeds teaching Hospitals NHS TrustVerified email at leeds.ac.uk
