The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into α and subsequently β cells P Collombat, X Xu, P Ravassard, B Sosa-Pineda, S Dussaud, N Billestrup, ... Cell 138 (3), 449-462, 2009 | 673 | 2009 |
Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro. N Billestrup, LW Swanson, W Vale Proceedings of the National Academy of Sciences 83 (18), 6854-6857, 1986 | 432 | 1986 |
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling TE Adams, JA Hansen, R Starr, NA Nicola, DJ Hilton, N Billestrup Journal of biological chemistry 273 (3), 1285-1287, 1998 | 393 | 1998 |
Growth Hormone, Interferon-γ, and Leukemia Inhibitory Factor Promoted Tyrosyl Phosphorylation of Insulin Receptor Substrate-1∗ LS Argetsinger, GW Hsu, MG Myers, N Billestrup, MF White, C Carter-Su Journal of Biological Chemistry 270 (24), 14685-14692, 1995 | 310 | 1995 |
Proliferation of sorted human and rat beta cells G Parnaud, D Bosco, T Berney, F Pattou, J Kerr-Conte, MY Donath, ... Diabetologia 51, 91-100, 2008 | 295 | 2008 |
Cytokines and β-cell biology: from concept to clinical translation MY Donath, J Størling, LA Berchtold, N Billestrup, T Mandrup-Poulsen Endocrine reviews 29 (3), 334-350, 2008 | 287 | 2008 |
Regulation of beta-cell mass by hormones and growth factors. JH Nielsen, ED Galsgaard, A Møldrup, BN Friedrichsen, N Billestrup, ... Diabetes 50 (suppl_1), S25, 2001 | 285 | 2001 |
The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH. LS Smit, DJ Meyer, N Billestrup, G Norstedt, J Schwartz, C Carter-Su Molecular endocrinology 10 (5), 519-533, 1996 | 281 | 1996 |
Proinflammatory cytokines activate the intrinsic apoptotic pathway in β-cells LG Grunnet, R Aikin, MF Tonnesen, S Paraskevas, L Blaabjerg, J Størling, ... Diabetes 58 (8), 1807-1815, 2009 | 275 | 2009 |
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus DP Christensen, M Dahllöf, M Lundh, DN Rasmussen, MD Nielsen, ... Molecular medicine 17, 378-390, 2011 | 273 | 2011 |
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins JA Hansen, K Lindberg, DJ Hilton, JH Nielsen, N Billestrup Molecular Endocrinology 13 (11), 1832-1843, 1999 | 267 | 1999 |
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling CJ Greenhalgh, D Metcalf, AL Thaus, JE Corbin, R Uren, PO Morgan, ... Journal of Biological Chemistry 277 (43), 40181-40184, 2002 | 217 | 2002 |
Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex H Frobøse, S Groth Rønn, PE Heding, H Mendoza, P Cohen, ... Molecular endocrinology 20 (7), 1587-1596, 2006 | 214 | 2006 |
Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase. JA VanderKuur, X Wang, L Zhang, GS Campbell, G Allevato, N Billestrup, ... Journal of Biological Chemistry 269 (34), 21709-21717, 1994 | 212 | 1994 |
Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2 (∗) J VanderKuur, G Allevato, N Billestrup, G Norstedt, C Carter-Su Journal of Biological Chemistry 270 (13), 7587-7593, 1995 | 202 | 1995 |
Beta cell proliferation and growth factors J Høiriis Nielsen, C Svensson, E Douglas Galsgaard, A Møldrup, ... Journal of molecular medicine 77, 62-66, 1999 | 190 | 1999 |
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt J Størling, J Binzer, AK Andersson, RA Züllig, M Tonnesen, R Lehmann, ... Diabetologia 48, 2039-2050, 2005 | 189 | 2005 |
Pituitary adenomas in mice transgenic for growth hormone-releasing hormone SL Asa, K Kovacs, L Stefaneanu, E Horvath, N Billestrup, ... Endocrinology 131 (5), 2083-2089, 1992 | 188 | 1992 |
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B MR Stofega, J Herrington, N Billestrup, C Carter-Su Molecular endocrinology 14 (9), 1338-1350, 2000 | 177 | 2000 |
Suppressor of cytokine signaling 3 (SOCS-3) protects β-cells against interleukin-1β-and interferon-γ-mediated toxicity AE Karlsen, SG Rønn, K Lindberg, J Johannesen, ED Galsgaard, F Pociot, ... Proceedings of the National Academy of Sciences 98 (21), 12191-12196, 2001 | 167 | 2001 |