| Somatic mutations in p85α promote tumorigenesis through class IA PI3K activation BS Jaiswal, V Janakiraman, NM Kljavin, S Chaudhuri, HM Stern, W Wang, ... Cancer cell 16 (6), 463-474, 2009 | 337 | 2009 |
| Connexins: a myriad of functions extending beyond assembly of gap junction channels HA Dbouk, RM Mroue, ME El-Sabban, RS Talhouk Cell Communication and Signaling 7, 1-17, 2009 | 324 | 2009 |
| G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ... Science signaling 5 (253), ra89-ra89, 2012 | 167 | 2012 |
| Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs) O Vadas, HA Dbouk, A Shymanets, O Perisic, JE Burke, WF Abi Saab, ... Proceedings of the National Academy of Sciences 110 (47), 18862-18867, 2013 | 154 | 2013 |
| Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation Z Dou, JA Pan, HA Dbouk, LM Ballou, JL DeLeon, Y Fan, JS Chen, ... Molecular cell 50 (1), 29-42, 2013 | 137 | 2013 |
| G protein-coupled receptors and the regulation of autophagy EM Wauson, HA Dbouk, AB Ghosh, MH Cobb Trends in Endocrinology & Metabolism 25 (5), 274-282, 2014 | 82 | 2014 |
| A biochemical mechanism for the oncogenic potential of the p110β catalytic subunit of phosphoinositide 3-kinase HA Dbouk, H Pang, A Fiser, JM Backer Proceedings of the National Academy of Sciences 107 (46), 19897-19902, 2010 | 71 | 2010 |
| Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK HA Dbouk, LM Weil, GKS Perera, MT Dellinger, G Pearson, RA Brekken, ... Proceedings of the National Academy of Sciences 111 (45), 15999-16004, 2014 | 64 | 2014 |
| Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of β-catenin/connexin43 association RS Talhouk, MB Fares, GJ Rahme, HH Hariri, T Rayess, HA Dbouk, ... Experimental cell research 319 (20), 3065-3080, 2013 | 56 | 2013 |
| A beta version of life: p110β takes center stage HA Dbouk, JM Backer Oncotarget 1 (8), 729, 2010 | 56 | 2010 |
| Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase HA Dbouk, BD Khalil, H Wu, A Shymanets, B Nürnberg, JM Backer PLoS One 8 (5), e63833, 2013 | 55 | 2013 |
| Significance of CEA and VEGF as diagnostic markers of colorectal cancer in Lebanese patients HA Dbouk, A Tawil, F Nasr, L Kandakarjian, R Abou-Merhi Open Clinical Cancer Journal 1, 1, 2007 | 35 | 2007 |
| PS-341 or a combination of arsenic trioxide and interferon-α inhibit growth and induce caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma cells R Abou-Merhi, R Khoriaty, D Arnoult, H El Hajj, H Dbouk, S Munier, ... Leukemia 21 (8), 1792-1801, 2007 | 30 | 2007 |
| Hypertension: the missing WNKs HA Dbouk, CL Huang, MH Cobb American Journal of Physiology-Renal Physiology 311 (1), F16-F27, 2016 | 27 | 2016 |
| Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5 RS Salamon, HA Dbouk, D Collado, J Lopiccolo, AR Bresnick, JM Backer Rab GTPases: Methods and Protocols, 271-281, 2015 | 14 | 2015 |
| Novel approaches to inhibitor design for the p110β phosphoinositide 3-kinase HA Dbouk, JM Backer Trends in pharmacological sciences 34 (3), 149-153, 2013 | 14 | 2013 |
| Control of podocyte and glomerular capillary wall structure and elasticity by WNK1 kinase Z Liu, J Yoon, C Wichaidit, AB Jaykumar, HA Dbouk, AE Embry, L Liu, ... Frontiers in Cell and Developmental Biology 8, 618898, 2021 | 8 | 2021 |
| An overview of familial Mediterranean fever with emphasis on pyrin and colchicine. HA Dbouk, IW Uthman Le Journal Medical libanais. The Lebanese Medical Journal 56 (1), 35-41, 2008 | 7 | 2008 |
| PI3Kβ downstream of GPCRs–crucial partners in oncogenesis HA Dbouk, O Vadas, RL Williams, JM Backer Oncotarget 3 (12), 1485-1486, 2012 | 6 | 2012 |
| PI3King the right partner: unique interactions and signaling by p110β HA Dbouk Postdoc journal: a journal of postdoctoral research and postdoctoral affairs …, 2015 | 4 | 2015 |
Roger L WilliamsGroup leader, Medical Research Council, Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
