| Role of proinflammatory cytokines in the pathophysiology of osteoarthritis M Kapoor, J Martel-Pelletier, D Lajeunesse, JP Pelletier, H Fahmi Nature Reviews Rheumatology 7 (1), 33-42, 2011 | 2764 | 2011 |
| Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs J Martel-Pelletier, D Lajeunesse, P Reboul, JP Pelletier Annals of the rheumatic diseases 62 (6), 501-509, 2003 | 581 | 2003 |
| Osteoblast‐like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis G Hilal, J Martel‐Pelletier, JP Pelletier, P Ranger, D Lajeunesse Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 283 | 1998 |
| Subchondral bone in osteoarthritis: a biologic link with articular cartilage leading to abnormal remodeling D Lajeunesse, P Reboul Current opinion in rheumatology 15 (5), 628-633, 2003 | 281 | 2003 |
| Targeting subchondral bone for treating osteoarthritis: what is the evidence? SK Tat, D Lajeunesse, JP Pelletier, J Martel-Pelletier Best Practice & Research Clinical Rheumatology 24 (1), 51-70, 2010 | 255 | 2010 |
| Can altered production of interleukin-1β, interleukin-6, transforming growth factor-β and prostaglandin E2 by isolated human subchondral osteoblasts identify two subgroups of … F Massicotte, D Lajeunesse, M Benderdour, JP Pelletier, G Hilal, N Duval, ... Osteoarthritis and cartilage 10 (6), 491-500, 2002 | 243 | 2002 |
| Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage M Moussa, D Lajeunesse, G Hilal, O El Atat, G Haykal, R Serhal, ... Experimental cell research 352 (1), 146-156, 2017 | 232 | 2017 |
| PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage F Vasheghani, Y Zhang, YH Li, M Blati, H Fahmi, B Lussier, P Roughley, ... Annals of the rheumatic diseases 74 (3), 569-578, 2015 | 217 | 2015 |
| IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis J Martel-Pelletier, JA Di Battista, D Lajeunesse, JP Pelletier Inflammation research 47 (3), 90-100, 1998 | 213 | 1998 |
| The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and … JP Pelletier, C Boileau, J Brunet, M Boily, D Lajeunesse, P Reboul, ... Bone 34 (3), 527-538, 2004 | 206 | 2004 |
| Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production D Couchourel, I Aubry, A Delalandre, M Lavigne, J Martel‐Pelletier, ... Arthritis & Rheumatism 60 (5), 1438-1450, 2009 | 187 | 2009 |
| Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study SK Tat, JP Pelletier, J Vergés, D Lajeunesse, E Montell, H Fahmi, ... Arthritis research & therapy 9, 1-10, 2007 | 176 | 2007 |
| Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis S Kwan Tat, N Amiable, JP Pelletier, C Boileau, D Lajeunesse, N Duval, ... Rheumatology 48 (12), 1482-1490, 2009 | 172 | 2009 |
| The role of bone in the treatment of osteoarthritis D Lajeunesse Osteoarthritis and cartilage 12, 34-38, 2004 | 170 | 2004 |
| The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor κB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an … SK Tat, JP Pelletier, D Lajeunesse, H Fahmi, M Lavigne, J Martel-Pelletier Clinical and experimental rheumatology 26 (2), 295, 2008 | 155 | 2008 |
| Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression MS Mutabaruka, M Aoulad Aissa, A Delalandre, M Lavigne, D Lajeunesse Arthritis research & therapy 12, 1-13, 2010 | 145 | 2010 |
| Osteocalcin secretion by the human osteosarcoma cell line MG‐63 D Lajeunesse, C Frondoza, B Schoffield, B Sacktor Journal of Bone and Mineral Research 5 (9), 915-922, 1990 | 145 | 1990 |
| Bone remodeling signaled by a dihydropyridine-and phenylalkylamine-sensitive calcium channel. SE Guggino, D Lajeunesse, JA Wagner, SH Snyder Proceedings of the National Academy of Sciences 86 (8), 2957-2960, 1989 | 136 | 1989 |
| Regulation of osteocalcin secretion by human primary bone cells and by the human osteosarcoma cell line MG-63 D Lajeunesse, GM Kiebzak, C Frondoza, B Sacktor Bone and mineral 14 (3), 237-250, 1991 | 125 | 1991 |
| Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model M Moreau, P Rialland, JP Pelletier, J Martel-Pelletier, D Lajeunesse, ... Arthritis research & therapy 13, 1-13, 2011 | 121 | 2011 |
Jacques A. de GuiseProfessor, École de technologie supérieure and CRCHUMVerified email at etsmtl.ca
