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Jason Cameron
Jason Cameron
Science Director, Albumedix Ltd
Verified email at albumedix.com - Homepage
Title
Cited by
Cited by
Year
Albumin as a versatile platform for drug half-life extension
D Sleep, J Cameron, LR Evans
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (12), 5526-5534, 2013
5252013
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
JT Andersen, B Dalhus, J Cameron, MB Daba, A Plumridge, L Evans, ...
Nature communications 3 (1), 610, 2012
2072012
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding
JT Andersen, B Dalhus, D Viuff, BT Ravn, KS Gunnarsen, A Plumridge, ...
Journal of Biological Chemistry 289 (19), 13492-13502, 2014
1832014
Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin
EGW Schmidt, ML Hvam, F Antunes, J Cameron, D Viuff, B Andersen, ...
Journal of Biological Chemistry 292 (32), 13312-13322, 2017
762017
Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin …
JT Andersen, J Cameron, A Plumridge, L Evans, D Sleep, I Sandlie
Journal of Biological Chemistry 288 (33), 24277-24285, 2013
682013
The production, characterisation and enhanced pharmacokinetics of scFv–albumin fusions expressed in Saccharomyces cerevisiae
L Evans, M Hughes, J Waters, J Cameron, N Dodsworth, D Tooth, ...
Protein expression and purification 73 (2), 113-124, 2010
572010
Albumin derivatives and variants
A Plumridge, D Sleep, I Sandlie, JT Andersen, J Cameron, L Evans, ...
US Patent 10,233,228, 2019
51*2019
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies
KMK Sand, B Dalhus, GJ Christianson, M Bern, S Foss, J Cameron, ...
Journal of Biological Chemistry 289 (24), 17228-17239, 2014
512014
Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs
D Viuff, F Antunes, L Evans, J Cameron, H Dyrnesli, BT Ravn, ...
Journal of Controlled Release 223, 22-30, 2016
502016
Albumin variants
A Plumridge, D Sleep, J Cameron, I Sandlie, JT Andersen, EP Friis
US Patent 8,748,380, 2014
502014
Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn)
KMK Sand, M Bern, J Nilsen, B Dalhus, KS Gunnarsen, J Cameron, ...
Journal of Biological Chemistry 289 (50), 34583-34594, 2014
492014
An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing
K Bienk, ML Hvam, MM Pakula, F Dagnæs-Hansen, J Wengel, BM Malle, ...
Journal of Controlled Release 232, 143-151, 2016
352016
FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs
MT Larsen, OA Mandrup, KK Schelde, Y Luo, KD Sørensen, ...
Journal of controlled release 322, 53-63, 2020
342020
Process for the purification of recombinant albumin
H Van Urk, DJ Mead, PH Morton, AJ Cartwright, J Cameron, DJ Ballance, ...
US Patent 7,993,877, 2011
322011
Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement
MT Larsen, H Rawsthorne, KK Schelde, F Dagnæs-Hansen, J Cameron, ...
Journal of controlled release 287, 132-141, 2018
312018
Albumin-based drug delivery using cysteine 34 chemical conjugates–important considerations and requirements
MB Caspersen, M Kuhlmann, K Nicholls, MJ Saxton, B Andersen, ...
Therapeutic delivery 8 (7), 511-519, 2017
292017
Albumin variants
JT Andersen, B Dalhus, I Sandlie, J Cameron, A Plumridge, EP Friis, ...
US Patent 8,822,417, 2014
262014
A critical examination of the role of surgery in the treatment of primary pulmonary tuberculosis in children
JK Cameron, JD Hay, LJ Temple
Thorax 12 (4), 329, 1957
261957
Site-selective conjugation of an anticoagulant aptamer to recombinant albumins and maintenance of neonatal Fc receptor binding
J Schmøkel, A Voldum, G Tsakiridou, M Kuhlmann, J Cameron, ...
Nanotechnology 28 (20), 204004, 2017
252017
Neonatal Fc receptor binding tolerance toward the covalent conjugation of payloads to cysteine 34 of human albumin variants
SS Petersen, E Klaning, MF Ebbesen, B Andersen, J Cameron, ...
Molecular pharmaceutics 13 (2), 677-682, 2016
242016
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