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C. Alexander Valencia, PhD
C. Alexander Valencia, PhD
Chief Clinical Officer, Aperiomics, Inc.
Verified email at aperiomics.com
Title
Cited by
Cited by
Year
Biparental inheritance of mitochondrial DNA in humans
S Luo, CA Valencia, J Zhang, NC Lee, J Slone, B Gui, X Wang, Z Li, ...
Proceedings of the National Academy of Sciences 115 (51), 13039-13044, 2018
4802018
Scanning the human proteome for calmodulin-binding proteins
X Shen, CA Valencia, J Szostak, B Dong, R Liu
Proceedings of the National Academy of Sciences 102 (17), 5969-5974, 2005
2152005
Clinical impact and cost-effectiveness of whole exome sequencing as a diagnostic tool: a pediatric center’s experience
CA Valencia, A Husami, J Holle, JA Johnson, Y Qian, A Mathur, C Wei, ...
Frontiers in pediatrics 3, 67, 2015
2102015
Enhanced detection of clinically relevant genomic imbalances using a targeted plus whole genome oligonucleotide microarray
EL Baldwin, JY Lee, DM Blake, BP Bunke, CR Alexander, AL Kogan, ...
Genetics in Medicine 10 (6), 415-429, 2008
1702008
Large-Scale Comparative Genomics Meta-Analysis of Campylobacter jejuni Isolates Reveals Low Level of Genome Plasticity
EN Taboada, RR Acedillo, CD Carrillo, WA Findlay, DT Medeiros, ...
Journal of clinical microbiology 42 (10), 4566-4576, 2004
1482004
Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis
K Zhang, S Chandrakasan, H Chapman, CA Valencia, A Husami, ...
Blood, The Journal of the American Society of Hematology 124 (8), 1331-1334, 2014
1422014
Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer
AJ Simnick, CA Valencia, R Liu, A Chilkoti
ACS nano 4 (4), 2217-2227, 2010
1222010
Potential role of exosome-associated microRNA panels and in vivo environment to predict drug resistance for patients with multiple myeloma
L Zhang, L Pan, B Xiang, H Zhu, Y Wu, M Chen, P Guan, X Zou, ...
Oncotarget 7 (21), 30876, 2016
1052016
Very long-chain acyl-coenzyme A dehydrogenase deficiency
ND Leslie, S Saenz-Ayala
972022
Comprehensive mutation analysis for congenital muscular dystrophy: a clinical PCR-based enrichment and next-generation sequencing panel
CA Valencia, A Ankala, D Rhodenizer, S Bhide, MR Littlejohn, LM Keong, ...
PloS one 8 (1), e53083, 2013
872013
Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells
RC Nayak, LR Trump, BJ Aronow, K Myers, P Mehta, T Kalfa, ...
The Journal of clinical investigation 125 (8), 3103-3116, 2015
822015
Highly-efficient purification of native polyhistidine-tagged proteins by multivalent NTA-modified magnetic nanoparticles
JS Kim, CA Valencia, R Liu, W Lin
Bioconjugate chemistry 18 (2), 333-341, 2007
712007
Assessment of Target Enrichment Platforms Using Massively Parallel Sequencing for the Mutation Detection for Congenital Muscular Dystrophy
CA Valencia, D Rhodenizer, S Bhide, E Chin, MR Littlejohn, LM Keong, ...
The Journal of Molecular Diagnostics, 2012
702012
Combined Immune Deficiency in a Patient with a Novel NFKB2 Mutation
AW Lindsley, Y Qian, CA Valencia, K Shah, K Zhang, A Assa’ad
Journal of clinical immunology 34, 910-915, 2014
692014
The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors
ZH Patel, LC Kottyan, S Lazaro, MS Williams, DH Ledbetter, G Tromp, ...
Frontiers in genetics 5, 76117, 2014
682014
Fibronectin type III domain based monobody with high avidity
J Duan, J Wu, CA Valencia, R Liu
Biochemistry 46 (44), 12656-12664, 2007
642007
Proteome-wide identification of family member-specific natural substrate repertoire of caspases
W Ju, CA Valencia, H Pang, Y Ke, W Gao, B Dong, R Liu
Proceedings of the National Academy of Sciences 104 (36), 14294-14299, 2007
582007
PAX1 is essential for development and function of the human thymus
Y Yamazaki, R Urrutia, LM Franco, S Giliani, K Zhang, AM Alazami, ...
Science Immunology 5 (44), eaax1036, 2020
572020
Ca2+/calmodulin directly interacts with the pleckstrin homology domain of AKT1
B Dong, CA Valencia, R Liu
Journal of Biological Chemistry 282 (34), 25131-25140, 2007
572007
Modulation of nucleobindin-1 and nucleobindin-2 by caspases
CA Valencia, SW Cotten, J Duan, R Liu
FEBS letters 582 (2), 286-290, 2008
552008
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