| Single tumor-initiating cells evade immune clearance by recruiting type II macrophages X Guo, Y Zhao, H Yan, Y Yang, S Shen, X Dai, X Ji, F Ji, XG Gong, L Li, ... Genes & development 31 (3), 247-259, 2017 | 240 | 2017 |
| Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 213 | 2020 |
| Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis X Dai, P She, F Chi, Y Feng, H Liu, D Jin, Y Zhao, X Guo, D Jiang, ... Journal of Biological Chemistry 288 (47), 34041-34051, 2013 | 176 | 2013 |
| Src inhibits the Hippo tumor suppressor pathway through tyrosine phosphorylation of Lats1 Y Si, X Ji, X Cao, X Dai, L Xu, H Zhao, X Guo, H Yan, H Zhang, C Zhu, ... Cancer research 77 (18), 4868-4880, 2017 | 137 | 2017 |
| Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade X Dai, X Bu, Y Gao, J Guo, J Hu, C Jiang, Z Zhang, K Xu, J Duan, S He, ... Molecular cell 81 (11), 2317-2331. e6, 2021 | 111 | 2021 |
| Copper Promotes Tumorigenesis by Activating the PDK1‐AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner J Guo, J Cheng, N Zheng, X Zhang, X Dai, L Zhang, C Hu, X Wu, Q Jiang, ... Advanced science 8 (18), 2004303, 2021 | 80 | 2021 |
| The diverse roles of SPOP in prostate cancer and kidney cancer Z Wang, Y Song, M Ye, X Dai, X Zhu, W Wei Nature Reviews Urology 17 (6), 339-350, 2020 | 72 | 2020 |
| LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control W Gan, X Dai, X Dai, J Xie, S Yin, J Zhu, C Wang, Y Liu, J Guo, M Wang, ... Nature cell biology 22 (2), 246-256, 2020 | 68 | 2020 |
| YAP activates the Hippo pathway in a negative feedback loop X Dai, H Liu, S Shen, X Guo, H Yan, X Ji, L Li, J Huang, XH Feng, B Zhao Cell research 25 (10), 1175-1178, 2015 | 68 | 2015 |
| RBR E3 ubiquitin ligases in tumorigenesis P Wang, X Dai, W Jiang, Y Li, W Wei Seminars in cancer biology 67, 131-144, 2020 | 58 | 2020 |
| Post-translational regulations of PD-L1 and PD-1: Mechanisms and opportunities for combined immunotherapy X Dai, Y Gao, W Wei Seminars in cancer biology 85, 246-252, 2022 | 45 | 2022 |
| PRDM 4 mediates YAP‐induced cell invasion by activating leukocyte‐specific integrin β2 expression H Liu, X Dai, X Cao, H Yan, X Ji, H Zhang, S Shen, Y Si, H Zhang, J Chen, ... EMBO reports 19 (6), e45180, 2018 | 43 | 2018 |
| S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions Q Jiang, X Zhang, X Dai, S Han, X Wu, L Wang, W Wei, N Zhang, W Xie, ... Nature communications 13 (1), 1548, 2022 | 26 | 2022 |
| Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1 T Zhang, D Xu, E Trefts, M Lv, H Inuzuka, G Song, M Liu, J Lu, J Liu, ... Science 380 (6652), 1372-1380, 2023 | 19 | 2023 |
| DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway L Liu, X Dai, S Yin, P Liu, EG Hill, W Wei, W Gan Science signaling 15 (715), eabh2290, 2022 | 17 | 2022 |
| PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity J Liu, X Bu, C Chu, X Dai, JM Asara, P Sicinski, GJ Freeman, W Wei Nature Communications 14 (1), 2806, 2023 | 15 | 2023 |
| YAP activates the Hippo pathway in a negative feedback loop X Dai, H Liu, S Shen, X Guo, H Yan, X Ji, L Li, J Huang, XH Feng, B Zhao Cell Research 27 (8), 1073, 2017 | 10 | 2017 |
| Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation T Zhang, D Xu, J Liu, M Wang, LJ Duan, M Liu, H Meng, Y Zhuang, ... Nature cell biology 25 (7), 950-962, 2023 | 8 | 2023 |
| AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation X Dai, C Jiang, Q Jiang, L Fang, H Yu, J Guo, P Yan, F Chi, T Zhang, ... Nature Metabolism 5 (2), 265-276, 2023 | 8 | 2023 |
| Ring domains are essential for GATOR2-dependent mTORC1 activation C Jiang, X Dai, S He, H Zhou, L Fang, J Guo, S Liu, T Zhang, W Pan, H Yu, ... Molecular Cell 83 (1), 74-89. e9, 2023 | 8 | 2023 |
Wenyi WeiProfessor, Dept. of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical SchoolVerified email at bidmc.harvard.edu
