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Temilolu Idowu
Temilolu Idowu
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Title
Cited by
Cited by
Year
Cefiderocol: a siderophore cephalosporin with activity against carbapenem-resistant and multidrug-resistant gram-negative bacilli
GG Zhanel, AR Golden, S Zelenitsky, K Wiebe, CK Lawrence, HJ Adam, ...
Drugs 79, 271-289, 2019
3482019
Antibiotic hybrids: the next generation of agents and adjuvants against Gram-negative pathogens?
R Domalaon, T Idowu, GG Zhanel, F Schweizer
Clinical microbiology reviews 31 (2), 10.1128/cmr. 00077-17, 2018
2842018
Ubiquitous nature of fluoroquinolones: the oscillation between antibacterial and anticancer activities
T Idowu, F Schweizer
Antibiotics 6 (4), 26, 2017
942017
Amphiphilic tobramycin–lysine conjugates sensitize multidrug resistant gram-negative bacteria to rifampicin and minocycline
Y Lyu, X Yang, S Goswami, BK Gorityala, T Idowu, R Domalaon, ...
Journal of medicinal chemistry 60 (9), 3684-3702, 2017
832017
Potentiation of β-lactam antibiotics and β-lactam/β-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin–cyclam conjugates
T Idowu, D Ammeter, G Arthur, GG Zhanel, F Schweizer
Journal of Antimicrobial Chemotherapy 74 (9), 2640-2648, 2019
382019
Heterodimeric rifampicin–tobramycin conjugates break intrinsic resistance of Pseudomonas aeruginosa to doxycycline and chloramphenicol in vitro and in a Galleria mellonella in …
T Idowu, G Arthur, GG Zhanel, F Schweizer
European journal of medicinal chemistry 174, 16-32, 2019
342019
Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-negative Bacteria
T Idowu, D Ammeter, H Rossong, GG Zhanel, F Schweizer
Journal of medicinal chemistry 62 (20), 9103-9115, 2019
302019
Amphiphilic modulation of glycosylated antitumor ether lipids results in a potent triamino scaffold against epithelial cancer cell lines and BT474 cancer stem cells
T Idowu, P Samadder, G Arthur, F Schweizer
Journal of medicinal chemistry 60 (23), 9724-9738, 2017
252017
Development of a nebramine-cyclam conjugate as an antibacterial adjuvant to potentiate β-lactam antibiotics against multidrug-resistant P. aeruginosa
D Ammeter, T Idowu, GG Zhanel, F Schweizer
The Journal of Antibiotics 72, 816-826, 2019
232019
Amphiphilic nebramine-based hybrids Rescue legacy antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli
X Yang, D Ammeter, T Idowu, R Domalaon, M Brizuela, O Okunnu, L Bi, ...
European journal of medicinal chemistry 175, 187-200, 2019
232019
Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)-chlorambucil-hybrids
T Idowu, P Samadder, G Arthur, F Schweizer
Chemistry and physics of lipids 194, 139-148, 2016
202016
Overcoming β-Lactam resistance in Pseudomonas aeruginosa using non-canonical tobramycin-based antibiotic adjuvants
T Idowu, D Ammeter, M Brizuela, G Jackson, S Alam, F Schweizer
Bioorganic & medicinal chemistry letters 30 (21), 127575, 2020
172020
Replacing d-Glucosamine with Its l-Enantiomer in Glycosylated Antitumor Ether Lipids (GAELs) Retains Cytotoxic Effects against Epithelial Cancer Cells and …
M Ogunsina, P Samadder, T Idowu, G Arthur, F Schweizer
Journal of Medicinal Chemistry 60 (5), 2142-2147, 2017
172017
Design, synthesis and evaluation of cytotoxic properties of bisamino glucosylated antitumor ether lipids against cancer cells and cancer stem cells
M Ogunsina, P Samadder, T Idowu, G Arthur, F Schweizer
MedChemComm 7 (11), 2100-2110, 2016
152016
A dimer, but not monomer, of tobramycin potentiates ceftolozane against multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa and delays resistance development
T Idowu, GG Zhanel, F Schweizer
Antimicrobial agents and chemotherapy 64 (3), 10.1128/aac. 02055-19, 2020
142020
Ursane-Type Triterpenes, Phenolics and Phenolic Derivatives from Globimetula braunii Leaf
AO Oriola, AJ Aladesanmi, TO Idowu, FO Akinwumi, EM Obuotor, T Idowu, ...
Molecules 26 (21), 6528, 2021
92021
Syntheses of l-Rhamnose-Linked Amino Glycerolipids and Their Cytotoxic Activities against Human Cancer Cells
M Ogunsina, P Samadder, T Idowu, M Nachtigal, F Schweizer, G Arthur
Molecules 25 (3), 566, 2020
72020
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens
JI Brown, R Persaud, P Iliev, U Karmacharya, S Attarha, H Sahile, ...
European Journal of Medicinal Chemistry 264, 115971, 2024
22024
Di-and tri-cationic glycosylated antitumor ether lipids, L-gucosylated gaels and rhamnose-linked gaels as cytotoxic agents against epithelial cancer cells and cancer stem cells
M Ogunsina, P Samadder, F Schweizer, G Arthur, T Idowu
US Patent 10,806,746, 2020
12020
Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent Against Gram-Negative Bacteria
F Schweizer, T Idowu
US Patent App. 17/611,974, 2022
2022
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