| Gut microbiota and intestinal FXR mediate the clinical benefits of metformin L Sun, C Xie, G Wang, Y Wu, Q Wu, X Wang, J Liu, Y Deng, J Xia, B Chen, ... Nature medicine 24 (12), 1919-1929, 2018 | 749 | 2018 |
| Farnesoid X receptor regulation of the NLRP3 inflammasome underlies cholestasis-associated sepsis H Hao, L Cao, C Jiang, Y Che, SY Zhang, S Takahashi, G Wang, ... Cell metabolism 25 (4), 856-867. e5, 2017 | 299 | 2017 |
| HIF1α-induced glycolysis metabolism is essential to the activation of inflammatory macrophages T Wang, H Liu, G Lian, SY Zhang, X Wang, C Jiang Mediators of inflammation 2017, 9029327, 2017 | 282 | 2017 |
| Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation Y Zhao, MM Zhao, Y Cai, MF Zheng, WL Sun, SY Zhang, W Kong, J Gu, ... Kidney international 88 (4), 711-721, 2015 | 118 | 2015 |
| Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism X Zhang, Y Zhang, P Wang, SY Zhang, Y Dong, G Zeng, Y Yan, L Sun, ... Cell metabolism 30 (5), 937-951. e5, 2019 | 101 | 2019 |
| Metabolomics analysis reveals that benzo[a]pyrene, a component of PM2.5, promotes pulmonary injury by modifying lipid metabolism in a phospholipase A2-dependent manner in vivo … SY Zhang, D Shao, H Liu, J Feng, B Feng, X Song, Q Zhao, M Chu, ... Redox biology 13, 459-469, 2017 | 87 | 2017 |
| Adipocyte-derived lysophosphatidylcholine activates adipocyte and adipose tissue macrophage nod-like receptor protein 3 inflammasomes mediating homocysteine-induced insulin … SY Zhang, YQ Dong, P Wang, X Zhang, Y Yan, L Sun, B Liu, D Zhang, ... EBioMedicine 31, 202-216, 2018 | 63 | 2018 |
| Novel adipokine, FAM19A5, inhibits neointima formation after injury through sphingosine-1-phosphate receptor 2 Y Wang, D Chen, Y Zhang, P Wang, C Zheng, SY Zhang, B Yu, L Zhang, ... Circulation 138 (1), 48-63, 2018 | 53 | 2018 |
| Adrenomedullin 2/intermedin: a putative drug candidate for treatment of cardiometabolic diseases SY Zhang, MJ Xu, X Wang British journal of pharmacology 175 (8), 1230-1240, 2018 | 53 | 2018 |
| Adrenomedullin 2 enhances beiging in white adipose tissue directly in an adipocyte-autonomous manner and indirectly through activation of M2 macrophages Y Lv, SY Zhang, X Liang, H Zhang, Z Xu, B Liu, MJ Xu, C Jiang, J Shang, ... Journal of biological chemistry 291 (45), 23390-23402, 2016 | 48 | 2016 |
| Intermedin/adrenomedullin 2 polypeptide promotes adipose tissue browning and reduces high-fat diet-induced obesity and insulin resistance in mice H Zhang, SY Zhang, C Jiang, Y Li, G Xu, MJ Xu, X Wang International Journal of Obesity 40 (5), 852-860, 2016 | 36 | 2016 |
| FXR in the dorsal vagal complex is sufficient and necessary for upper small intestinal microbiome-mediated changes of TCDCA to alter insulin action in rats SY Zhang, RJW Li, YM Lim, B Batchuluun, H Liu, TMZ Waise, TKT Lam Gut 70 (9), 1675-1683, 2021 | 33 | 2021 |
| Adrenomedullin 2 improves early obesity-induced adipose insulin resistance by inhibiting the class II MHC in adipocytes SY Zhang, Y Lv, H Zhang, S Gao, T Wang, J Feng, Y Wang, G Liu, MJ Xu, ... Diabetes 65 (8), 2342-2355, 2016 | 30 | 2016 |
| Intermedin restores hyperhomocysteinemia-induced macrophage polarization and improves insulin resistance in mice Y Pang, Y Li, Y Lv, L Sun, SY Zhang, Y Li, Y Wang, G Liu, MJ Xu, X Wang, ... Journal of biological chemistry 291 (23), 12336-12345, 2016 | 28 | 2016 |
| Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity FF Anhê, S Zlitni, SY Zhang, BSY Choi, CY Chen, KP Foley, NG Barra, ... Gut 72 (3), 460-471, 2023 | 27 | 2023 |
| Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production TMZ Waise, M Rasti, FA Duca, SY Zhang, PV Bauer, CJ Rhodes, ... Nature communications 10 (1), 714, 2019 | 22 | 2019 |
| Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight SY Zhang, K Bruce, Z Danaei, RJW Li, DR Barros, R Kuah, YM Lim, ... Cell Metabolism 35 (5), 875-886. e5, 2023 | 20 | 2023 |
| Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner Y Yan, X Wu, P Wang, SY Zhang, L Sun, Y Zhao, GY Zeng, B Liu, G Xu, ... Redox biology 37, 101742, 2020 | 20 | 2020 |
| Interaction of glucose sensing and leptin action in the brain RJW Li, SY Zhang, TKT Lam Molecular metabolism 39, 101011, 2020 | 20 | 2020 |
| Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation P Wang, G Zeng, Y Yan, SY Zhang, Y Dong, Y Zhang, X Zhang, H Liu, ... Acta Pharmaceutica Sinica B 12 (4), 1899-1912, 2022 | 18 | 2022 |
