Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2598 | 2014 |
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised … L Klareskog, D van der Heijde, JP de Jager, A Gough, J Kalden, ... The Lancet 363 (9410), 675-681, 2004 | 2334 | 2004 |
Tumor necrosis factor antagonist mechanisms of action: a comprehensive review D Tracey, L Klareskog, EH Sasso, JG Salfeld, PP Tak Pharmacology & therapeutics 117 (2), 244-279, 2008 | 2187 | 2008 |
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullination L Klareskog, P Stolt, K Lundberg, H Källberg, C Bengtsson, J Grunewald, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 2054 | 2006 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010 | 1605 | 2010 |
STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007 | 1344 | 2007 |
EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics … B Combe, R Landewé, C Lukas, HD Bolosiu, F Breedveld, M Dougados, ... Annals of the rheumatic diseases 66 (1), 34-45, 2007 | 1209 | 2007 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1163 | 2019 |
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis S Raychaudhuri, C Sandor, EA Stahl, J Freudenberg, HS Lee, X Jia, ... Nature genetics 44 (3), 291-296, 2012 | 1112 | 2012 |
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis Y Liu, MJ Aryee, L Padyukov, MD Fallin, E Hesselberg, A Runarsson, ... Nature biotechnology 31 (2), 142-147, 2013 | 1105 | 2013 |
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis E Baecklund, A Iliadou, J Askling, A Ekbom, C Backlin, F Granath, ... Arthritis & Rheumatism 54 (3), 692-701, 2006 | 1070 | 2006 |
TRAF1–C5 as a risk locus for rheumatoid arthritis—a genomewide study RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, ... New England Journal of Medicine 357 (12), 1199-1209, 2007 | 1062 | 2007 |
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa HJ Watson, Z Yilmaz, LM Thornton, C Hübel, JRI Coleman, HA Gaspar, ... Nature genetics 51 (8), 1207-1214, 2019 | 925 | 2019 |
A gene–environment interaction between smoking and shared epitope genes in HLA–DR provides a high risk of seropositive rheumatoid arthritis L Padyukov, C Silva, P Stolt, L Alfredsson, L Klareskog Arthritis & Rheumatism: Official Journal of the American College of …, 2004 | 918 | 2004 |
Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases P Stolt, C Bengtsson, B Nordmark, S Lindblad, I Lundberg, L Klareskog, ... Annals of the rheumatic diseases 62 (9), 835-841, 2003 | 902 | 2003 |
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin U Harre, D Georgess, H Bang, A Bozec, R Axmann, E Ossipova, ... The Journal of clinical investigation 122 (5), 1791-1802, 2012 | 878 | 2012 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 788 | 2012 |
Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L) GS Alarcón, G McGwin, AM Bertoli, BJ Fessler, J Calvo-Alén, HM Bastian, ... Annals of the rheumatic diseases 66 (9), 1168-1172, 2007 | 760* | 2007 |
Incidence of cancer among patients with rheumatoid arthritis G Gridley, JK McLaughlin, A Ekbom, L Klareskog, HO Adami, DG Hacker, ... JNCI: Journal of the National Cancer Institute 85 (4), 307-311, 1993 | 753 | 1993 |
Replication of putative candidate-gene associations with rheumatoid arthritis in> 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4 … RM Plenge, L Padyukov, EF Remmers, S Purcell, AT Lee, EW Karlson, ... The American Journal of Human Genetics 77 (6), 1044-1060, 2005 | 742 | 2005 |